메뉴 건너뛰기




Volumn 10, Issue 1, 2009, Pages 143-150

Genistein mechanisms and timing of prostate cancer chemoprevention in Lobund-Wistar rats

Author keywords

Chemoprevention; Genistein; Prostate cancer; Rat model

Indexed keywords


EID: 67650911933     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (19)

References (52)
  • 1
    • 0028849729 scopus 로고
    • Phytoestrogens: epidemiology and a possible role in cancer protection
    • Adlercreutz H, (1995). Phytoestrogens: epidemiology and a possible role in cancer protection. Env Health Persp, 103, 103-112.
    • (1995) Env Health Persp , vol.103 , pp. 103-112
    • Adlercreutz, H.1
  • 2
    • 0025859857 scopus 로고
    • Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein
    • Adlercreutz H, Fotsis T, Bannwart C, et al, (1991). Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. Clinica Chimica Acta, 199, 263-78.
    • (1991) Clinica Chimica Acta , vol.199 , pp. 263-278
    • Adlercreutz, H.1    Fotsis, T.2    Bannwart, C.3
  • 3
    • 0027383287 scopus 로고
    • Plasma concentrations of phyto-estrogens in Japanese men
    • Adlercreutz H, Markkanen H, Watanabe S, (1993). Plasma concentrations of phyto-estrogens in Japanese men. Lancet, 342, 1209-10.
    • (1993) Lancet , vol.342 , pp. 1209-1210
    • Adlercreutz, H.1    Markkanen, H.2    Watanabe, S.3
  • 4
    • 0023664272 scopus 로고
    • A specific inhibitor of tyrosine-specific protein kinases
    • Akiyama T, Ishida J, Nakagawa S, et al, (1987). A specific inhibitor of tyrosine-specific protein kinases. J Biol Chem, 262, 5592-5.
    • (1987) J Biol Chem , vol.262 , pp. 5592-5595
    • Akiyama, T.1    Ishida, J.2    Nakagawa, S.3
  • 6
    • 0025019367 scopus 로고
    • Induction of dorsolateral prostate adenocarcinomas and other accessory sex gland lesions in male Wistar rats by a single administration of Nmethyl-N nitrosourea, 7,12- dimethylbenz[a]-anthracene, and 3,2'- dimethyl-4-amino-biphenyldimethyl-4-aminobiphenyl after sequential treatment with cyproterone acetate and testosterone propionate
    • Bosland MC, Prinsen MK, (1990). Induction of dorsolateral prostate adenocarcinomas and other accessory sex gland lesions in male Wistar rats by a single administration of Nmethyl-N nitrosourea, 7,12- dimethylbenz[a]-anthracene, and 3,2'- dimethyl-4-amino-biphenyldimethyl-4-aminobiphenyl after sequential treatment with cyproterone acetate and testosterone propionate. Cancer Res, 50, 691-9.
    • (1990) Cancer Res , vol.50 , pp. 691-699
    • Bosland, M.C.1    Prinsen, M.K.2
  • 7
    • 0033582929 scopus 로고    scopus 로고
    • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
    • Brunet A, Bonni A, Zigmond MJ, et al, (1999). Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell, 96, 857-68.
    • (1999) Cell , vol.96 , pp. 857-868
    • Brunet, A.1    Bonni, A.2    Zigmond, M.J.3
  • 8
    • 0029160069 scopus 로고
    • Protein, kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BM, Coffer PJ, (1995). Protein, kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature, 376, 599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 9
    • 33645983347 scopus 로고    scopus 로고
    • Inhibitory effect of isoflavones on prostate cancer cells and PTEN gene
    • Cao F, Jin TY, Zhou YF, (2006). Inhibitory effect of isoflavones on prostate cancer cells and PTEN gene. Biomed Environ Sci, 19, 35-41.
    • (2006) Biomed Environ Sci , vol.19 , pp. 35-41
    • Cao, F.1    Jin, T.Y.2    Zhou, Y.F.3
  • 10
    • 0032515027 scopus 로고    scopus 로고
    • Regulation of cell death protease caspase-9 by phosphorylation
    • Cardone MH, Roy N, Stennicke HR, et al, (1998). Regulation of cell death protease caspase-9 by phosphorylation. Science, 282, 1318-21.
    • (1998) Science , vol.282 , pp. 1318-1321
    • Cardone, M.H.1    Roy, N.2    Stennicke, H.R.3
  • 11
    • 0028928687 scopus 로고
    • Genistein as an inducer of tumor cell differentiation: possible mechanisms of action
    • Constantinou A, Huberman E, (1995). Genistein as an inducer of tumor cell differentiation: possible mechanisms of action. Proc Soc Exp Biol Med, 208, 109-15.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 109-115
    • Constantinou, A.1    Huberman, E.2
  • 12
    • 0032846010 scopus 로고    scopus 로고
    • Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants
    • Cook LS, Goldoft M, Schwartz SM, et al, (1999). Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants. J Urol, 161, 152-5.
    • (1999) J Urol , vol.161 , pp. 152-155
    • Cook, L.S.1    Goldoft, M.2    Schwartz, S.M.3
  • 13
    • 0242439518 scopus 로고    scopus 로고
    • Role of the androgen receptor axis in prostate cancer
    • Culig Z, (2003). Role of the androgen receptor axis in prostate cancer. Urology, 62 (S 5A), 21-6.
    • (2003) Urology , vol.62 , Issue.S 5A , pp. 21-26
    • Culig, Z.1
  • 14
    • 0031880755 scopus 로고    scopus 로고
    • Genistein, a component of soy, inhibits the expression of the EGF and ErbB/Neu receptors in the rat dorsolateral prostate
    • Dalu A, Haskell JF, Coward L, et al, (1998). Genistein, a component of soy, inhibits the expression of the EGF and ErbB/Neu receptors in the rat dorsolateral prostate. Prostate, 37, 36-43.
    • (1998) Prostate , vol.37 , pp. 36-43
    • Dalu, A.1    Haskell, J.F.2    Coward, L.3
  • 15
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery
    • Datta SR, Dudek H, Tao X, et al, (1997). Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery. Cell, 91, 231-41.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3
  • 16
    • 0033152165 scopus 로고    scopus 로고
    • Regulation of Akt/ PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
    • Davies MA, Koul D, Dhesi H, et al, (1999). Regulation of Akt/ PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res, 59, 2551-6.
    • (1999) Cancer Res , vol.59 , pp. 2551-2556
    • Davies, M.A.1    Koul, D.2    Dhesi, H.3
  • 17
    • 0032456061 scopus 로고    scopus 로고
    • Genistein- induced upregulation of p21WAF1, downregulation of cyclinB, and induction of apoptosis in prostate cancer cells
    • Davis JN, Singh B, Bhuiyan M, et al, (1998). Genistein- induced upregulation of p21WAF1, downregulation of cyclinB, and induction of apoptosis in prostate cancer cells. Nutr Cancer, 32, 123-31.
    • (1998) Nutr Cancer , vol.32 , pp. 123-131
    • Davis, J.N.1    Singh, B.2    Bhuiyan, M.3
  • 18
    • 0029873670 scopus 로고    scopus 로고
    • Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer
    • Denmeade SR, Lin XS, Isaacs JT, (1996). Role of programmed (apoptotic) cell death during the progression and therapy for prostate cancer. Prostate, 28, 251-65.
    • (1996) Prostate , vol.28 , pp. 251-265
    • Denmeade, S.R.1    Lin, X.S.2    Isaacs, J.T.3
  • 19
    • 0034920457 scopus 로고    scopus 로고
    • Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer
    • Depowski PL, Rosenthal SI, Ross JS, (2001). Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer. Mod Pathol, 14, 672-6.
    • (2001) Mod Pathol , vol.14 , pp. 672-676
    • Depowski, P.L.1    Rosenthal, S.I.2    Ross, J.S.3
  • 20
    • 0036738462 scopus 로고    scopus 로고
    • PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium
    • Dupont J, Renou JP, Shani M, et al, (2002). PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium. J Clin Inv, 110, 815-25.
    • (2002) J Clin Inv , vol.110 , pp. 815-825
    • Dupont, J.1    Renou, J.P.2    Shani, M.3
  • 21
    • 0027464720 scopus 로고
    • Genistein, a dietary derived inhibitor of in vitro angiogenesis
    • Fotsis T, Pepper M, Adlercreutz H, et al, (1993). Genistein, a dietary derived inhibitor of in vitro angiogenesis. Proc Natl Acad Sci USA, 90, 2690-4.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2690-2694
    • Fotsis, T.1    Pepper, M.2    Adlercreutz, H.3
  • 22
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGFactivate phosphatidylinositol 3-kinase
    • Franke TF, Yang SI, Chan TO, et al, (1995). The protein kinase encoded by the Akt proto-oncogene is a target of the PDGFactivate phosphatidylinositol 3-kinase. Cell, 81, 727-36.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.I.2    Chan, T.O.3
  • 23
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR, Cantley LC, (1997). PI3K: downstream AKTion blocks apoptosis. Cell, 88, 435-7.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 24
    • 0032437643 scopus 로고    scopus 로고
    • Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat
    • Fritz WA, Coward L, Wang J, et al, (1998). Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat. Carcinogenesis, 19, 2151-8.
    • (1998) Carcinogenesis , vol.19 , pp. 2151-2158
    • Fritz, W.A.1    Coward, L.2    Wang, J.3
  • 25
    • 0037081891 scopus 로고    scopus 로고
    • Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate
    • Fritz WA, Wang J, Eltoum IE, et al, (2002). Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate. Mol Cell Endo, 186, 89-99.
    • (2002) Mol Cell Endo , vol.186 , pp. 89-99
    • Fritz, W.A.1    Wang, J.2    Eltoum, I.E.3
  • 26
    • 0031659121 scopus 로고    scopus 로고
    • In vivo time course of morphological changes and DNA degradation during the degeneration of castration-induced apoptotic prostate cells
    • Hu Z, Ito T, Yuri K, et al, (1998). In vivo time course of morphological changes and DNA degradation during the degeneration of castration-induced apoptotic prostate cells. Cell Tissue Res, 294, 153-60.
    • (1998) Cell Tissue Res , vol.294 , pp. 153-160
    • Hu, Z.1    Ito, T.2    Yuri, K.3
  • 27
    • 0036195968 scopus 로고    scopus 로고
    • Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate
    • Lamartiniere CA, Cotroneo MS, Fritz WA, et al, (2002). Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate. J Nutr, 132, 552S-8S.
    • (2002) J Nutr , vol.132
    • Lamartiniere, C.A.1    Cotroneo, M.S.2    Fritz, W.A.3
  • 28
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Lia, D, et al, (1997). PTEN, a putative tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275, 1943-7.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Lia, D.3
  • 29
    • 0035827510 scopus 로고    scopus 로고
    • Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells
    • Li P, Nicosia SV, Bai W, (2001). Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells. J Biol Chem, 276, 20444-50.
    • (2001) J Biol Chem , vol.276 , pp. 20444-20450
    • Li, P.1    Nicosia, S.V.2    Bai, W.3
  • 30
    • 0033587157 scopus 로고    scopus 로고
    • Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein
    • Li Y, Upadhyay S, Bhuiyan M, et al, (1999). Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein. Oncogene, 18, 3166-72.
    • (1999) Oncogene , vol.18 , pp. 3166-3172
    • Li, Y.1    Upadhyay, S.2    Bhuiyan, M.3
  • 31
    • 0035992417 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway
    • Li Y, Sarkar FH, (2002). Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clin Cancer Res, 8, 2369-77.
    • (2002) Clin Cancer Res , vol.8 , pp. 2369-2377
    • Li, Y.1    Sarkar, F.H.2
  • 32
    • 0030963042 scopus 로고    scopus 로고
    • Lignans and isoflavonoids in plasma and prostatic fluid in men: samples from Portugal, Hong Kong, and the United Kingdom
    • Morton MS, Chan PS, Cheng C, et al, (1997). Lignans and isoflavonoids in plasma and prostatic fluid in men: samples from Portugal, Hong Kong, and the United Kingdom. Prostate, 32, 122-8.
    • (1997) Prostate , vol.32 , pp. 122-128
    • Morton, M.S.1    Chan, P.S.2    Cheng, C.3
  • 33
    • 0042854862 scopus 로고    scopus 로고
    • The PTEN tumor suppressor is a negative modulator of androgen receptor transcriptional activity
    • Nan B, Snabboon T, Unni E, et al, (2003). The PTEN tumor suppressor is a negative modulator of androgen receptor transcriptional activity. J Mol End, 31, 169-83.
    • (2003) J Mol End , vol.31 , pp. 169-183
    • Nan, B.1    Snabboon, T.2    Unni, E.3
  • 34
    • 0028150702 scopus 로고
    • Growth-inhibitory effects of the natural phyto-oestrogen genistein in MCF-7 human breast cancer cells
    • Pagliacci MC, Smacchia M, Migliorati G, et al, (1994). Growth-inhibitory effects of the natural phyto-oestrogen genistein in MCF-7 human breast cancer cells. Eur J Cancer, 30A, 1675-82.
    • (1994) Eur J Cancer , vol.30 A , pp. 1675-1682
    • Pagliacci, M.C.1    Smacchia, M.2    Migliorati, G.3
  • 35
    • 0015759137 scopus 로고
    • Spontaneous prostate adenocarcinomas in aged germ free Wistar rats
    • Pollard M, (1973). Spontaneous prostate adenocarcinomas in aged germ free Wistar rats. J Natl Cancer Inst, 51, 1235-41.
    • (1973) J Natl Cancer Inst , vol.51 , pp. 1235-1241
    • Pollard, M.1
  • 36
    • 0022458410 scopus 로고
    • Production of autochthonous prostate cancer on L-W rats by treatments with N-nitroso-N-methylurea and testosterone
    • Pollard M, Luckert PH, (1986). Production of autochthonous prostate cancer on L-W rats by treatments with N-nitroso-N-methylurea and testosterone. J Natl Cancer Inst, 77, 583-7.
    • (1986) J Natl Cancer Inst , vol.77 , pp. 583-587
    • Pollard, M.1    Luckert, P.H.2
  • 37
    • 0031903933 scopus 로고    scopus 로고
    • Lobund-Wistar rat model of prostate cancer in man
    • Pollard M, (1998). Lobund-Wistar rat model of prostate cancer in man. Prostate, 37, 1-4.
    • (1998) Prostate , vol.37 , pp. 1-4
    • Pollard, M.1
  • 38
    • 0344627287 scopus 로고
    • Comparative aspects of development and structures in the prostate
    • Price D, (1963). Comparative aspects of development and structures in the prostate. Natl Cancer Inst Monogr, 12, 1-18.
    • (1963) Natl Cancer Inst Monogr , vol.12 , pp. 1-18
    • Price, D.1
  • 39
    • 0027463424 scopus 로고
    • Immunocytochemical analysis of androgen receptor along the ducts of the separate rat prostate lobes after androgen withdrawal and replacement
    • Prins GS, Birch L, (1993). Immunocytochemical analysis of androgen receptor along the ducts of the separate rat prostate lobes after androgen withdrawal and replacement. Endocrinology, 132, 169-78.
    • (1993) Endocrinology , vol.132 , pp. 169-178
    • Prins, G.S.1    Birch, L.2
  • 40
    • 0033026714 scopus 로고    scopus 로고
    • Mechanisms of apoptosis avoidance in cancer
    • Reed JC, (1999). Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol, 11, 68-75.
    • (1999) Curr Opin Oncol , vol.11 , pp. 68-75
    • Reed, J.C.1
  • 41
    • 0025769201 scopus 로고
    • Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County
    • Shimizu H, Ross RK, Bernstein L, et al, (1991). Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County. Br J Cancer, 63, 963-6.
    • (1991) Br J Cancer , vol.63 , pp. 963-966
    • Shimizu, H.1    Ross, R.K.2    Bernstein, L.3
  • 42
    • 4344698040 scopus 로고    scopus 로고
    • PTENless means more
    • Stiles B, Groszer M, Wang S, et al, (2004). PTENless means more. Dev Biol, 273, 175-84.
    • (2004) Dev Biol , vol.273 , pp. 175-184
    • Stiles, B.1    Groszer, M.2    Wang, S.3
  • 43
    • 0032475861 scopus 로고    scopus 로고
    • Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
    • Stambolic V, Suzuki A, de la Pompa JL et al, (1998). Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell, 95, 29-39.
    • (1998) Cell , vol.95 , pp. 29-39
    • Stambolic, V.1    Suzuki, A.2    de la Pompa, J.L.3
  • 44
    • 0037163032 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3 inhibition and nuclear β-catenin accumulation
    • Sharma M, Chuang WW, Sun Z, (2002). Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3 inhibition and nuclear β-catenin accumulation. J Biol Chem, 277, 30935-41.
    • (2002) J Biol Chem , vol.277 , pp. 30935-30941
    • Sharma, M.1    Chuang, W.W.2    Sun, Z.3
  • 45
    • 0030057663 scopus 로고    scopus 로고
    • Intravenous vs. intraprostatic administration of N-methy-N-nitrosourea to induce prostate cancer in rats
    • Schleicher RL, Fallon MT, Austin G, et al, (1996). Intravenous vs. intraprostatic administration of N-methy-N-nitrosourea to induce prostate cancer in rats. Prostate, 28, 32-43.
    • (1996) Prostate , vol.28 , pp. 32-43
    • Schleicher, R.L.1    Fallon, M.T.2    Austin, G.3
  • 46
    • 0034914622 scopus 로고    scopus 로고
    • Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women
    • Shu XO, Jin F, Dai Q, et al, (2001). Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women. Cancer Epidemiol Biomarkers Prev, 10, 483-8.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 483-488
    • Shu, X.O.1    Jin, F.2    Dai, Q.3
  • 47
    • 0035835824 scopus 로고    scopus 로고
    • PTEN: Life as a tumor suppressor
    • Simpson L, Parsons R, (2001). PTEN: Life as a tumor suppressor. Exp Cell Res, 264, 29-41.
    • (2001) Exp Cell Res , vol.264 , pp. 29-41
    • Simpson, L.1    Parsons, R.2
  • 48
    • 0036883592 scopus 로고    scopus 로고
    • Dietary genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats
    • Wang J, Eltoum IE, Lamarteniere CA, (2002). Dietary genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats. Cancer Lett, 186, 11-8.
    • (2002) Cancer Lett , vol.186 , pp. 11-18
    • Wang, J.1    Eltoum, I.E.2    Lamarteniere, C.A.3
  • 49
    • 0034655083 scopus 로고    scopus 로고
    • E-7869 (Rflurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse
    • Wechter WJ, Leipold DD, Murray ED, et al, (2000). E-7869 (Rflurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse. Cancer Res, 60, 2203-8.
    • (2000) Cancer Res , vol.60 , pp. 2203-2208
    • Wechter, W.J.1    Leipold, D.D.2    Murray, E.D.3
  • 50
    • 0028944947 scopus 로고
    • Antioxidant and antipromotional effects of the soybean isoflavone genistein
    • Wei H, Bowen R, Cai Q, et al, (1995). Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc Soc Exp Biol Med, 208, 124-130.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 124-130
    • Wei, H.1    Bowen, R.2    Cai, Q.3
  • 51
    • 0033571477 scopus 로고    scopus 로고
    • PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death
    • Weng LP, Smith WM, Dahia PLM, et al, (1999). PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. Cancer Res, 59, 5808-14.
    • (1999) Cancer Res , vol.59 , pp. 5808-5814
    • Weng, L.P.1    Smith, W.M.2    Dahia, P.L.M.3
  • 52
    • 0037050231 scopus 로고    scopus 로고
    • PTEN sensitizes prostate cancer cells to death receptor-mediated and drug- induced apoptosis through a FADD-dependent pathway
    • Yuan XJ, Wang YE, (2002). PTEN sensitizes prostate cancer cells to death receptor-mediated and drug- induced apoptosis through a FADD-dependent pathway. Oncogene, 21, 319-27.
    • (2002) Oncogene , vol.21 , pp. 319-327
    • Yuan, X.J.1    Wang, Y.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.