-
1
-
-
67650743221
-
Biosynthesis of phosphonic and phosphinic acid natural products
-
Metcalf WW, van der Donk WA. 2009. Biosynthesis of phosphonic and phosphinic acid natural products. Annu. Rev. Biochem. 78:65-94
-
(2009)
Annu. Rev. Biochem
, vol.78
, pp. 65-94
-
-
Metcalf, W.W.1
van der Donk, W.A.2
-
2
-
-
0032468984
-
Bisphosphonates: Mechanisms of action
-
Fleisch H. 1998. Bisphosphonates: mechanisms of action. Endocr. Rev. 19:80-100
-
(1998)
Endocr. Rev
, vol.19
, pp. 80-100
-
-
Fleisch, H.1
-
3
-
-
0031800988
-
Mechanisms of action of bisphosphonates
-
Rodan GA. 1998. Mechanisms of action of bisphosphonates. Annu. Rev. Pharmacol. Toxicol. 38:375-88
-
(1998)
Annu. Rev. Pharmacol. Toxicol
, vol.38
, pp. 375-388
-
-
Rodan, G.A.1
-
4
-
-
0014684354
-
Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo
-
Fleisch H, Russell RG, Francis MD. 1969. Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science 165:1262-64
-
(1969)
Science
, vol.165
, pp. 1262-1264
-
-
Fleisch, H.1
Russell, R.G.2
Francis, M.D.3
-
5
-
-
0014684364
-
Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo
-
Francis MD, Russell RG, Fleisch H. 1969. Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo. Science 165:1264-66
-
(1969)
Science
, vol.165
, pp. 1264-1266
-
-
Francis, M.D.1
Russell, R.G.2
Fleisch, H.3
-
6
-
-
1842405434
-
Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro
-
Frith JC, Monkkonen J, Blackburn GM, Russell RG, Rogers MJ. 1997. Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro. J. Bone Miner. Res. 12:1358-67
-
(1997)
J. Bone Miner. Res
, vol.12
, pp. 1358-1367
-
-
Frith, J.C.1
Monkkonen, J.2
Blackburn, G.M.3
Russell, R.G.4
Rogers, M.J.5
-
7
-
-
0033958778
-
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase
-
Bergstrom JD, Bostedor RG, Masarachia PJ, Reszka AA, Rodan G. 2000. Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase. Arch. Biochem. Biophys. 373:231-41
-
(2000)
Arch. Biochem. Biophys
, vol.373
, pp. 231-241
-
-
Bergstrom, J.D.1
Bostedor, R.G.2
Masarachia, P.J.3
Reszka, A.A.4
Rodan, G.5
-
8
-
-
0033554651
-
Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates
-
van Beek E, Pieterman E, Cohen L, Lowik C, Papapoulos S. 1999. Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates. Biochem. Biophys. Res. Commun. 264:108-11
-
(1999)
Biochem. Biophys. Res. Commun
, vol.264
, pp. 108-111
-
-
van Beek, E.1
Pieterman, E.2
Cohen, L.3
Lowik, C.4
Papapoulos, S.5
-
9
-
-
65749091606
-
New antivirals and drug resistance
-
Colman PM. 2009. New antivirals and drug resistance. Annu. Rev. Biochem. 78:95-118
-
(2009)
Annu. Rev. Biochem
, vol.78
, pp. 95-118
-
-
Colman, P.M.1
-
10
-
-
0038107450
-
Zanamivir in the treatment of influenza
-
Fleming DM. 2003. Zanamivir in the treatment of influenza. Expert Opin. Pharmacother. 4:799-805
-
(2003)
Expert Opin. Pharmacother
, vol.4
, pp. 799-805
-
-
Fleming, D.M.1
-
11
-
-
0032996541
-
Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers
-
Cass LM, Efthymiopoulos C, Bye A. 1999. Pharmacokinetics of zanamivir after intravenous, oral, inhaled or intranasal administration to healthy volunteers. Clin. Pharmacokinet. 36(Suppl. 1):1-11
-
(1999)
Clin. Pharmacokinet
, vol.36
, Issue.SUPPL. 1
, pp. 1-11
-
-
Cass, L.M.1
Efthymiopoulos, C.2
Bye, A.3
-
12
-
-
0034758713
-
Oseltamivir: A clinical and pharmacological perspective
-
Doucette KE, Aoki FY. 2001. Oseltamivir: a clinical and pharmacological perspective. Expert Opin. Pharmacother. 2:1671-83
-
(2001)
Expert Opin. Pharmacother
, vol.2
, pp. 1671-1683
-
-
Doucette, K.E.1
Aoki, F.Y.2
-
13
-
-
0033385681
-
Clinical pharmacokinetics of the prodrug oseltamivir and its active metabolite Ro 64-0802
-
He G, Massarella J, Ward P. 1999. Clinical pharmacokinetics of the prodrug oseltamivir and its active metabolite Ro 64-0802. Clin. Pharmacokinet. 37:471-84
-
(1999)
Clin. Pharmacokinet
, vol.37
, pp. 471-484
-
-
He, G.1
Massarella, J.2
Ward, P.3
-
14
-
-
0031916471
-
Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitorGS4071
-
Li W, Escarpe PA, Eisenberg EJ, Cundy KC, Sweet C, et al. 1998. Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitorGS4071. Antimicrob. Agents Chemother. 42:647-53
-
(1998)
Antimicrob. Agents Chemother
, vol.42
, pp. 647-653
-
-
Li, W.1
Escarpe, P.A.2
Eisenberg, E.J.3
Cundy, K.C.4
Sweet, C.5
-
15
-
-
67649616421
-
GS-8374, a novel phosphonate HIV protease inhibitor with potent in vitro antiretroviral activity, low metabolic toxicity, and favorable resistance profile
-
Callebaut C, Stray K, Tsai L, Xu L, He GX, et al. 2007. GS-8374, a novel phosphonate HIV protease inhibitor with potent in vitro antiretroviral activity, low metabolic toxicity, and favorable resistance profile. Antivir. Res. 74:A27
-
(2007)
Antivir. Res
, vol.74
-
-
Callebaut, C.1
Stray, K.2
Tsai, L.3
Xu, L.4
He, G.X.5
-
16
-
-
33749240210
-
Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring
-
Cihlar T, He GX, Liu X, Chen JM, Hatada M, et al. 2006. Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring. J. Mol. Biol. 363:635-47
-
(2006)
J. Mol. Biol
, vol.363
, pp. 635-647
-
-
Cihlar, T.1
He, G.X.2
Liu, X.3
Chen, J.M.4
Hatada, M.5
-
17
-
-
0037569181
-
Enfuvirtide, a new drug for HIV infection
-
Fletcher CV. 2003. Enfuvirtide, a new drug for HIV infection. Lancet 361:1577-78
-
(2003)
Lancet
, vol.361
, pp. 1577-1578
-
-
Fletcher, C.V.1
-
18
-
-
65249146929
-
Multidrug resistance in bacteria
-
Nikaido H. 2009. Multidrug resistance in bacteria. Annu. Rev. Biochem. 78:119-46
-
(2009)
Annu. Rev. Biochem
, vol.78
, pp. 119-146
-
-
Nikaido, H.1
-
19
-
-
0034769921
-
Bacteriophage therapy
-
Summers WC. 2001. Bacteriophage therapy. Annu. Rev. Microbiol. 55:437-51
-
(2001)
Annu. Rev. Microbiol
, vol.55
, pp. 437-451
-
-
Summers, W.C.1
-
20
-
-
0035172666
-
Bacteriophages as therapeutic agents
-
Sulakvelidze A, Morris JG Jr. 2001. Bacteriophages as therapeutic agents. Ann. Med. 33:507-9
-
(2001)
Ann. Med
, vol.33
, pp. 507-509
-
-
Sulakvelidze, A.1
Morris Jr., J.G.2
-
21
-
-
0038808883
-
The prospect for bacteriophage therapy in Western medicine
-
Merril CR, Scholl D, Adhya SL. 2003. The prospect for bacteriophage therapy in Western medicine. Nat. Rev. Drug Discov. 2:489-97
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, pp. 489-497
-
-
Merril, C.R.1
Scholl, D.2
Adhya, S.L.3
-
23
-
-
0023619963
-
Oxazolidinones, a new class of synthetic antibacterial agents: In vitro and in vivo activities of DuP 105 and DuP 721
-
Slee AM, Wuonola MA, McRipley RJ, Zajac I, Zawada MJ, et al. 1987. Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and DuP 721. Antimicrob. Agents Chemother. 31:1791-97
-
(1987)
Antimicrob. Agents Chemother
, vol.31
, pp. 1791-1797
-
-
Slee, A.M.1
Wuonola, M.A.2
McRipley, R.J.3
Zajac, I.4
Zawada, M.J.5
-
24
-
-
0030944770
-
Oxazolidinones: New antibacterial agents
-
Ford CW, Hamel JC, Stapert D, Moerman JK, Hutchinson DK, et al. 1997. Oxazolidinones: new antibacterial agents. Trends Microbiol. 5:196-200
-
(1997)
Trends Microbiol
, vol.5
, pp. 196-200
-
-
Ford, C.W.1
Hamel, J.C.2
Stapert, D.3
Moerman, J.K.4
Hutchinson, D.K.5
-
25
-
-
49649108541
-
Molecular characterisation of linezolid resistance in two vancomycin-resistant (VanB) Enterococcus faecium isolates using Pyrosequencing
-
Saager B, Rohde H, Timmerbeil BS, Franke G, Pothmann W, et al. 2008. Molecular characterisation of linezolid resistance in two vancomycin-resistant (VanB) Enterococcus faecium isolates using Pyrosequencing. Eur. J. Clin. Microbiol. Infect Dis. 27:873-78
-
(2008)
Eur. J. Clin. Microbiol. Infect Dis
, vol.27
, pp. 873-878
-
-
Saager, B.1
Rohde, H.2
Timmerbeil, B.S.3
Franke, G.4
Pothmann, W.5
-
26
-
-
42049096982
-
Linezolid resistance in Staphylococcus aureus: Gene dosage effect, stability, fitness costs, and cross-resistances
-
Besier S, Ludwig A, Zander J, Brade V, Wichelhaus TA. 2008. Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. Antimicrob. Agents Chemother. 52:1570-72
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, pp. 1570-1572
-
-
Besier, S.1
Ludwig, A.2
Zander, J.3
Brade, V.4
Wichelhaus, T.A.5
-
27
-
-
44449125584
-
First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States
-
Mendes RE, Deshpande LM, Castanheira M, DiPersio J, Saubolle MA, Jones RN. 2008. First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. Antimicrob. Agents Chemother. 52:2244-46
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, pp. 2244-2246
-
-
Mendes, R.E.1
Deshpande, L.M.2
Castanheira, M.3
DiPersio, J.4
Saubolle, M.A.5
Jones, R.N.6
-
31
-
-
0033790259
-
Development of daptomycin for gram-positive infections
-
Tally FP, DeBruin MF. 2000. Development of daptomycin for gram-positive infections. J. Antimicrob. Chemother. 46:523-26
-
(2000)
J. Antimicrob. Chemother
, vol.46
, pp. 523-526
-
-
Tally, F.P.1
DeBruin, M.F.2
-
33
-
-
57049134826
-
Serial daptomycin selection generates daptomycinnonsusceptible Staphylococcus aureus strains with a heterogeneous vancomycin-intermediate phenotype
-
Camargo IL, Neoh HM, Cui L, Hiramatsu K. 2008. Serial daptomycin selection generates daptomycinnonsusceptible Staphylococcus aureus strains with a heterogeneous vancomycin-intermediate phenotype. Antimicrob. Agents Chemother. 52:4289-99
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, pp. 4289-4299
-
-
Camargo, I.L.1
Neoh, H.M.2
Cui, L.3
Hiramatsu, K.4
-
34
-
-
33746755334
-
Tigecycline: First of a new class of antimicrobial agents
-
Rose WE, Rybak MJ. 2006. Tigecycline: first of a new class of antimicrobial agents. Pharmacotherapy 26:1099-110
-
(2006)
Pharmacotherapy
, vol.26
, pp. 1099-1110
-
-
Rose, W.E.1
Rybak, M.J.2
-
35
-
-
0035487002
-
Glycylcyclines: Third-generation tetracycline antibiotics
-
Chopra I. 2001. Glycylcyclines: third-generation tetracycline antibiotics. Curr. Opin. Pharmacol. 1:464-69
-
(2001)
Curr. Opin. Pharmacol
, vol.1
, pp. 464-469
-
-
Chopra, I.1
-
36
-
-
34249977996
-
High tigecycline resistance in multidrug-resistant Acinetobacter baumannii
-
Navon-Venezia S, Leavitt A, Carmeli Y. 2007. High tigecycline resistance in multidrug-resistant Acinetobacter baumannii. J. Antimicrob. Chemother. 59:772-74
-
(2007)
J. Antimicrob. Chemother
, vol.59
, pp. 772-774
-
-
Navon-Venezia, S.1
Leavitt, A.2
Carmeli, Y.3
-
37
-
-
34250799619
-
An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site
-
Rock FL, Mao W, Yaremchuk A, Tukalo M, Crepin T, et al. 2007. An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site. Science 316:1759-61
-
(2007)
Science
, vol.316
, pp. 1759-1761
-
-
Rock, F.L.1
Mao, W.2
Yaremchuk, A.3
Tukalo, M.4
Crepin, T.5
-
38
-
-
58249100113
-
Transcription inactivation through local refolding of the RNA polymerase structure
-
Belogurov GA, Vassylyeva MN, Sevostyanova A, Appleman JR, Xiang AX, et al. 2009. Transcription inactivation through local refolding of the RNA polymerase structure. Nature 457:332-35
-
(2009)
Nature
, vol.457
, pp. 332-335
-
-
Belogurov, G.A.1
Vassylyeva, M.N.2
Sevostyanova, A.3
Appleman, J.R.4
Xiang, A.X.5
-
39
-
-
25444522227
-
Molecular chaperones in protein quality control
-
Lee S, Tsai FT. 2005. Molecular chaperones in protein quality control. J. Biochem. Mol. Biol. 38:259-65
-
(2005)
J. Biochem. Mol. Biol
, vol.38
, pp. 259-265
-
-
Lee, S.1
Tsai, F.T.2
-
41
-
-
67650713938
-
Conformational pathology of the serpins: Themes, variations, and therapeutic strategies
-
Gooptu B, Lomas DA. 2009. Conformational pathology of the serpins: themes, variations, and therapeutic strategies. Annu. Rev. Biochem. 78:147-76
-
(2009)
Annu. Rev. Biochem
, vol.78
, pp. 147-176
-
-
Gooptu, B.1
Lomas, D.A.2
-
42
-
-
0042023711
-
Alzheimer disease in the US population: Prevalence estimates using the 2000 census
-
Hebert LE, Scherr PA, Bienias JL, Bennett DA, Evans DA. 2003. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch. Neurol. 60:1119-22
-
(2003)
Arch. Neurol
, vol.60
, pp. 1119-1122
-
-
Hebert, L.E.1
Scherr, P.A.2
Bienias, J.L.3
Bennett, D.A.4
Evans, D.A.5
-
43
-
-
0029110883
-
The chemistry of scrapie infection: Implications of the 'ice 9' metaphor
-
Lansbury PT Jr, Caughey B. 1995. The chemistry of scrapie infection: implications of the 'ice 9' metaphor. Chem. Biol. 2:1-5
-
(1995)
Chem. Biol
, vol.2
, pp. 1-5
-
-
Lansbury Jr, P.T.1
Caughey, B.2
-
44
-
-
0033055254
-
Ice-nine and human prion disease
-
Coyle JT. 1999. Ice-nine and human prion disease. Harv. Rev. Psychiatry 6:331-33
-
(1999)
Harv. Rev. Psychiatry
, vol.6
, pp. 331-333
-
-
Coyle, J.T.1
-
46
-
-
67650747654
-
Getting a grip on prions: Oligomers, amyloids and pathological membrane interactions
-
Caughey B, Baron GS, Chesebro B, Jeffery M. 2009. Getting a grip on prions: oligomers, amyloids and pathological membrane interactions. Annu. Rev. Biochem. 78:177-204
-
(2009)
Annu. Rev. Biochem
, vol.78
, pp. 177-204
-
-
Caughey, B.1
Baron, G.S.2
Chesebro, B.3
Jeffery, M.4
-
47
-
-
34249941302
-
Copper and the prion protein: Methods, structures, function, and disease
-
Millhauser GL. 2007. Copper and the prion protein: methods, structures, function, and disease. Annu. Rev. Phys. Chem. 58:299-320
-
(2007)
Annu. Rev. Phys. Chem
, vol.58
, pp. 299-320
-
-
Millhauser, G.L.1
-
48
-
-
40449128239
-
The chemistry of copper binding to PrP: Is there sufficient evidence to elucidate a role for copper in protein function?
-
Davies P, Brown DR. 2008. The chemistry of copper binding to PrP: Is there sufficient evidence to elucidate a role for copper in protein function? Biochem. J. 410:237-44
-
(2008)
Biochem. J
, vol.410
, pp. 237-244
-
-
Davies, P.1
Brown, D.R.2
-
49
-
-
0345306739
-
Copper chelation delays the onset of prion disease
-
Sigurdsson EM, Brown DR, Alim MA, Scholtzova H, Carp R, et al. 2003. Copper chelation delays the onset of prion disease. J. Biol. Chem. 278:46199-202
-
(2003)
J. Biol. Chem
, vol.278
, pp. 46199-46202
-
-
Sigurdsson, E.M.1
Brown, D.R.2
Alim, M.A.3
Scholtzova, H.4
Carp, R.5
-
51
-
-
50249175120
-
Chemical and biological approaches synergize to ameliorate protein-folding diseases
-
Mu TW, Ong DS, Wang YJ, Balch WE, Yates JR 3rd, et al. 2008. Chemical and biological approaches synergize to ameliorate protein-folding diseases. Cell 134:769-81
-
(2008)
Cell
, vol.134
, pp. 769-781
-
-
Mu, T.W.1
Ong, D.S.2
Wang, Y.J.3
Balch, W.E.4
Yates 3rd, J.R.5
-
52
-
-
28244502156
-
Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: A focus on the transthyretin amyloidoses
-
Johnson SM, Wiseman RL, Sekijima Y, Green NS, Adamski-Werner SL, Kelly JW. 2005. Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: a focus on the transthyretin amyloidoses. Acc. Chem. Res. 38:911-21
-
(2005)
Acc. Chem. Res
, vol.38
, pp. 911-921
-
-
Johnson, S.M.1
Wiseman, R.L.2
Sekijima, Y.3
Green, N.S.4
Adamski-Werner, S.L.5
Kelly, J.W.6
-
53
-
-
38349124133
-
Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors
-
Johnson SM, Connelly S, Wilson IA, Kelly JW. 2008. Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors. J. Med. Chem. 51:260-70
-
(2008)
J. Med. Chem
, vol.51
, pp. 260-270
-
-
Johnson, S.M.1
Connelly, S.2
Wilson, I.A.3
Kelly, J.W.4
-
54
-
-
48749132287
-
Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria
-
Pey AL, Ying M, Cremades N, Velazquez-Campoy A, Scherer T, et al. 2008. Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria. J. Clin. Investig. 118:2858-67
-
(2008)
J. Clin. Investig
, vol.118
, pp. 2858-2867
-
-
Pey, A.L.1
Ying, M.2
Cremades, N.3
Velazquez-Campoy, A.4
Scherer, T.5
-
55
-
-
33745293617
-
Therapeutic strategies to ameliorate lysosomal storage disorders - a focus on Gaucher disease
-
Sawkar AR, D'Haeze W, Kelly JW. 2006. Therapeutic strategies to ameliorate lysosomal storage disorders - a focus on Gaucher disease. Cell Mol. Life Sci. 63:1179-92
-
(2006)
Cell Mol. Life Sci
, vol.63
, pp. 1179-1192
-
-
Sawkar, A.R.1
D'Haeze, W.2
Kelly, J.W.3
-
56
-
-
59449109683
-
Identification of pharmacological chaperones for Gaucher disease and characterization of their effects on beta-glucocerebrosidase by hydrogen/deuterium exchange mass spectrometry
-
Tropak MB, Kornhaber GJ, Rigat BA, Maegawa GH, Buttner JD, et al. 2008. Identification of pharmacological chaperones for Gaucher disease and characterization of their effects on beta-glucocerebrosidase by hydrogen/deuterium exchange mass spectrometry. ChemBioChem 9:2650-62
-
(2008)
ChemBioChem
, vol.9
, pp. 2650-2662
-
-
Tropak, M.B.1
Kornhaber, G.J.2
Rigat, B.A.3
Maegawa, G.H.4
Buttner, J.D.5
-
57
-
-
34748914170
-
Pharmacologic chaperoning as a strategy to treat Gaucher disease
-
Yu Z, Sawkar AR, Kelly JW. 2007. Pharmacologic chaperoning as a strategy to treat Gaucher disease. FEBS J. 274:4944-50
-
(2007)
FEBS J
, vol.274
, pp. 4944-4950
-
-
Yu, Z.1
Sawkar, A.R.2
Kelly, J.W.3
-
58
-
-
33846265304
-
Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention
-
Yu Z, Sawkar AR, Whalen LJ, Wong CH, Kelly JW. 2007. Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention. J. Med. Chem. 50:94-100
-
(2007)
J. Med. Chem
, vol.50
, pp. 94-100
-
-
Yu, Z.1
Sawkar, A.R.2
Whalen, L.J.3
Wong, C.H.4
Kelly, J.W.5
-
59
-
-
34548650256
-
Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease
-
Zheng W, Padia J, Urban DJ, Jadhav A, Goker-Alpan O, et al. 2007. Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. Proc. Natl. Acad. Sci. USA 104:13192-97
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 13192-13197
-
-
Zheng, W.1
Padia, J.2
Urban, D.J.3
Jadhav, A.4
Goker-Alpan, O.5
-
60
-
-
33847032037
-
High-throughput screening for human lysosomal beta-N-Acetyl hexosaminidase inhibitors acting as pharmacological chaperones
-
Tropak MB, Blanchard JE, Withers SG, Brown ED, Mahuran D. 2007. High-throughput screening for human lysosomal beta-N-Acetyl hexosaminidase inhibitors acting as pharmacological chaperones. Chem. Biol. 14:153-64
-
(2007)
Chem. Biol
, vol.14
, pp. 153-164
-
-
Tropak, M.B.1
Blanchard, J.E.2
Withers, S.G.3
Brown, E.D.4
Mahuran, D.5
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