Loss of Wip1 sensitizes cells to stress- and DNA damage-induced apoptosis

Journal of Biological Chemistry

Volumn 284, Issue 26, 2009, Pages 17428-17437

  Xia, Yun ^a   Ongusaha, Pat ^b   Lee, Sam W ^b   Liou, Yih Cherng ^a,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c NONE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CELL-FATE; DNA DAMAGES; DUAL ROLE; ENVIRONMENTAL STRESS; GENE DISRUPTIONS; INDUCED APOPTOSIS; MOUSE EMBRYONIC FIBROBLASTS; STRESS-INDUCED; TUMORIGENESIS;

CELL CULTURE; CELL MEMBRANES; DNA; GENES; NUCLEIC ACIDS; SIGNALING; TRANSCRIPTION; TRANSCRIPTION FACTORS;

CELL DEATH;

ACTIVATING TRANSCRIPTION FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN P53; PROTEIN WIP1; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL STRESS; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; ENZYME ACTIVATION; FIBROBLAST; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; ANISOMYCIN; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELLS, CULTURED; DNA DAMAGE; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; ETOPOSIDE; FAS LIGAND PROTEIN; FIBROBLASTS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; NUCLEIC ACID SYNTHESIS INHIBITORS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-JUN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; STAUROSPORINE; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 67650558427     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.007823     Document Type: Article

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