-
2
-
-
0033180108
-
Biosynthesis of polyketides (other than actinomycete macrolides)
-
Rawlings, B. J. Biosynthesis of polyketides (other than actinomycete macrolides). Nat. Prod. Rep. 1999, 16, 425-484.
-
(1999)
Nat. Prod. Rep
, vol.16
, pp. 425-484
-
-
Rawlings, B.J.1
-
3
-
-
0000142261
-
Structure, function, and engineering of bacterial aromatic polyketide synthases
-
Richardson, M.; Khosla, C. Structure, function, and engineering of bacterial aromatic polyketide synthases. Comor. Nat. Prod. Chem. 1999, 1, 473-494.
-
(1999)
Comor. Nat. Prod. Chem
, vol.1
, pp. 473-494
-
-
Richardson, M.1
Khosla, C.2
-
4
-
-
0000427346
-
Biosynthesis of aromatic polyketides
-
Shen, B. Biosynthesis of aromatic polyketides. Top. Curr. Chem. 2000, 209, 1-51.
-
(2000)
Top. Curr. Chem
, vol.209
, pp. 1-51
-
-
Shen, B.1
-
5
-
-
33846923183
-
Type II polyketide synthases: Gaining a deeper insight into enzymatic teamwork
-
Hertweck, C.; Luzhetskyy, A.; Rebets, Y.; Bechthold, A. Type II polyketide synthases: Gaining a deeper insight into enzymatic teamwork. Nat. Prod. Rep. 2007, 24, 162-190.
-
(2007)
Nat. Prod. Rep
, vol.24
, pp. 162-190
-
-
Hertweck, C.1
Luzhetskyy, A.2
Rebets, Y.3
Bechthold, A.4
-
6
-
-
0036007875
-
Biosynthesis and attachment of novel bacterial polyketide synthase starter units
-
Moore, B. S.; Hertweck, C. Biosynthesis and attachment of novel bacterial polyketide synthase starter units. Nat. Prod. Rep. 2002, 19, 70-99.
-
(2002)
Nat. Prod. Rep
, vol.19
, pp. 70-99
-
-
Moore, B.S.1
Hertweck, C.2
-
7
-
-
0003869903
-
-
The John Innes Foundation: Norwich, U.K
-
Kieser, T.; Bibb, M. J.; Buttner, M. J.; Chater, K. F.; Hopwood, D. A. Practical Streptomyces Genetics; The John Innes Foundation: Norwich, U.K., 2000.
-
(2000)
Practical Streptomyces Genetics
-
-
Kieser, T.1
Bibb, M.J.2
Buttner, M.J.3
Chater, K.F.4
Hopwood, D.A.5
-
8
-
-
0001747786
-
Genetic contributions to understanding polyketide synthases
-
Hopwood, D. A. Genetic contributions to understanding polyketide synthases. Chem. Rev. 1997, 97, 2465-2498.
-
(1997)
Chem. Rev
, vol.97
, pp. 2465-2498
-
-
Hopwood, D.A.1
-
9
-
-
0021238139
-
Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host
-
Malpartida, F.; Hopwood, D. A. Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host. Nature 1984, 309, 462-464.
-
(1984)
Nature
, vol.309
, pp. 462-464
-
-
Malpartida, F.1
Hopwood, D.A.2
-
10
-
-
0026657813
-
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin
-
Fernandez-Moreno, M. A.; Martinez, E.; Boto, L.; Hopwood, D. A.; Malpartida, F. Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin. J. Biol. Chem. 1992, 267, 19278-19290.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 19278-19290
-
-
Fernandez-Moreno, M.A.1
Martinez, E.2
Boto, L.3
Hopwood, D.A.4
Malpartida, F.5
-
11
-
-
0032562124
-
Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase
-
Carreras, C. W.; Khosla, C. Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase. Biochemistry 1998, 37, 2084-2088.
-
(1998)
Biochemistry
, vol.37
, pp. 2084-2088
-
-
Carreras, C.W.1
Khosla, C.2
-
12
-
-
0029125339
-
Malonyl-coenzyme A: Acyl carrier protein acyltransferase of Streptomyces glaucescens: A possible link between fatty acid and polyketide biosynthesis
-
Summers, R. G.; Ali, A.; Shen, B.; Wessel, W. A.; Hutchinson, C. R. Malonyl-coenzyme A: acyl carrier protein acyltransferase of Streptomyces glaucescens: A possible link between fatty acid and polyketide biosynthesis. Biochemistry 1995, 34, 9389-9402.
-
(1995)
Biochemistry
, vol.34
, pp. 9389-9402
-
-
Summers, R.G.1
Ali, A.2
Shen, B.3
Wessel, W.A.4
Hutchinson, C.R.5
-
13
-
-
15844385423
-
Efficient synthesis of aromatic polyketides in vitro by the actinorhodin polyketide synthase
-
Carreras, C. W.; Pieper, R.; Khosla, C. Efficient synthesis of aromatic polyketides in vitro by the actinorhodin polyketide synthase. J. Am. Chem. Soc. 1996, 118, 5158-5159.
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 5158-5159
-
-
Carreras, C.W.1
Pieper, R.2
Khosla, C.3
-
14
-
-
0027908014
-
Engineered biosynthesis of novel polvketides
-
McDaniel, R.; Ebert-Khosla, S.; Hopwood, D. A.; Khosla, C. Engineered biosynthesis of novel polvketides. Science 1993, 262, 1546-1550.
-
(1993)
Science
, vol.262
, pp. 1546-1550
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
15
-
-
0034721884
-
Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism
-
Marti, T.; Hu, Z.; Pohl, N. L.; Shah, A. N.; Khosla, C. Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism. J. Biol. Chem. 2000, 275, 33443-33448.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 33443-33448
-
-
Marti, T.1
Hu, Z.2
Pohl, N.L.3
Shah, A.N.4
Khosla, C.5
-
16
-
-
66149121114
-
-
GenBank accession number AF058302.
-
GenBank accession number AF058302.
-
-
-
-
17
-
-
0028351394
-
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin
-
Bibb, M. J.; Sherman, D. H.; Omura, S.; Hopwood, D. A. Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin. Gene 1994, 142, 31-39.
-
(1994)
Gene
, vol.142
, pp. 31-39
-
-
Bibb, M.J.1
Sherman, D.H.2
Omura, S.3
Hopwood, D.A.4
-
18
-
-
0034728380
-
Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer
-
Dreier, J.; Khosla, C. Mechanistic analysis of a type II polyketide synthase. Role of conserved residues in the beta-ketoacyl synthase-chain length factor heterodimer. Biochemistry 2000, 39, 2088-2095.
-
(2000)
Biochemistry
, vol.39
, pp. 2088-2095
-
-
Dreier, J.1
Khosla, C.2
-
19
-
-
4344578939
-
An antibiotic factory caught in action
-
Keatinge-Clay, A. T.; Maltby, D. A.; Medzihradszky, K. F.; Khosla, C.; Stroud, R. M. An antibiotic factory caught in action. Nat. Struct. Mol. Biol. 2004, 11, 888-893.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 888-893
-
-
Keatinge-Clay, A.T.1
Maltby, D.A.2
Medzihradszky, K.F.3
Khosla, C.4
Stroud, R.M.5
-
20
-
-
0142135988
-
Polyketide chain length control by chain length factor
-
Tang, Y.; Tsai, S. C.; Khosla, C. Polyketide chain length control by chain length factor. J. Am. Chem. Soc. 2003, 125, 12708-12709.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 12708-12709
-
-
Tang, Y.1
Tsai, S.C.2
Khosla, C.3
-
21
-
-
42449158575
-
Evolution of polyketide synthases in bacteria
-
Ridley, C. P.; Lee, H. Y.; Khosla, C. Evolution of polyketide synthases in bacteria. Proc. Natl. Acad Sci. U.S.A. 2008, 105, 4595-4600.
-
(2008)
Proc. Natl. Acad Sci. U.S.A
, vol.105
, pp. 4595-4600
-
-
Ridley, C.P.1
Lee, H.Y.2
Khosla, C.3
-
22
-
-
0033609915
-
Kinetic analysis of the actinorhodin aromatic polvketide svnthase
-
Dreier, J.; Shah, A. N.; Khosla, C. Kinetic analysis of the actinorhodin aromatic polvketide svnthase. J. Biol. Chem. 1999, 274, 25108-25112.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 25108-25112
-
-
Dreier, J.1
Shah, A.N.2
Khosla, C.3
-
23
-
-
28444466613
-
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus
-
Chem. Soc
-
Wendt-Pienkowski, E.; Huang, Y.; Zhang, J.; Li, B.; Jiang, H.; Kwon, H.; Hutchinson, C. R.; Shen, B. Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus. J. Am. Chem. Soc. 2005, 127, 16442-16452.
-
(2005)
J. Am
, vol.127
, pp. 16442-16452
-
-
Wendt-Pienkowski, E.1
Huang, Y.2
Zhang, J.3
Li, B.4
Jiang, H.5
Kwon, H.6
Hutchinson, C.R.7
Shen, B.8
-
24
-
-
0027746346
-
Engineered biosynthesis of novel polyketides: Manipulation and analysis of an aromatic polyketide synthase with unproven catalytic specificities
-
McDaniel, R.; Khosla, S. E.; Hopwood, D. A.; Khosla, C. Engineered biosynthesis of novel polyketides: Manipulation and analysis of an aromatic polyketide synthase with unproven catalytic specificities. J. Am. Chem. Soc. 1993, 115, 11671-11675.
-
(1993)
J. Am. Chem. Soc
, vol.115
, pp. 11671-11675
-
-
McDaniel, R.1
Khosla, S.E.2
Hopwood, D.A.3
Khosla, C.4
-
25
-
-
0027970295
-
Engineered biosynthesis of novel polyketides: Influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase
-
McDaniel, R.; Ebert-Khosla, S.; Fu, H.; Hopwood, D. A.; Khosla, C. Engineered biosynthesis of novel polyketides: Influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 11542-11565.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A
, vol.91
, pp. 11542-11565
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Fu, H.3
Hopwood, D.A.4
Khosla, C.5
-
26
-
-
0028575694
-
Engineered biosynthesis of novel polyketides: Act VII and act IV genes encode aromatase and cyclase enzymes, respectively
-
McDaniel, R.; Khosla, S. E.; Hopwood, D. A.; Khosla, C. Engineered biosynthesis of novel polyketides: act VII and act IV genes encode aromatase and cyclase enzymes, respectively. J. Am. Chem. Soc. 1994, 116, 10855-10859.
-
(1994)
J. Am. Chem. Soc
, vol.116
, pp. 10855-10859
-
-
McDaniel, R.1
Khosla, S.E.2
Hopwood, D.A.3
Khosla, C.4
-
27
-
-
0029064652
-
Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits
-
McDaniel, R.; Ebert-Khosla, S.; Hopwood, D. A.; Khosla, C. Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits. Nature 1995, 375, 549-554.
-
(1995)
Nature
, vol.375
, pp. 549-554
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
28
-
-
0031047160
-
Rational design and engineered biosynthesis of a novel 18-carbon aromatic polyketide
-
Kramer, P. J.; Zawada, R. J. X.; McDaniel, R.; Hutchinson, C. R.; Hopwood, D. A.; Khosla, C. Rational design and engineered biosynthesis of a novel 18-carbon aromatic polyketide. J. Am. Chem. Soc. 1997, 119, 635-639.
-
(1997)
J. Am. Chem. Soc
, vol.119
, pp. 635-639
-
-
Kramer, P.J.1
Zawada, R.J.X.2
McDaniel, R.3
Hutchinson, C.R.4
Hopwood, D.A.5
Khosla, C.6
-
29
-
-
19344369476
-
Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthases
-
Tang, Y.; Lee, T. S.; Khosla, C. Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthases. PLoS Biol. 2004, 2, E31.
-
(2004)
PLoS Biol
, vol.2
-
-
Tang, Y.1
Lee, T.S.2
Khosla, C.3
-
30
-
-
3242738853
-
Exploring the biosynthetic potential of bimodular aromatic polyketide synthases
-
Tang, Y.; Lee, T. S.; Lee, H. Y.; Khosla, C. Exploring the biosynthetic potential of bimodular aromatic polyketide synthases. Tetrahedron 2004, 60, 7659-7671.
-
(2004)
Tetrahedron
, vol.60
, pp. 7659-7671
-
-
Tang, Y.1
Lee, T.S.2
Lee, H.Y.3
Khosla, C.4
-
31
-
-
24644478020
-
Engineered biosynthesis of aklanonic acid analogues
-
Lee, T. S.; Khosla, C.; Tang, Y. Engineered biosynthesis of aklanonic acid analogues. J. Am. Chem. Soc. 2005, 127, 12254-12262.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 12254-12262
-
-
Lee, T.S.1
Khosla, C.2
Tang, Y.3
-
32
-
-
0037714370
-
Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity
-
Tang, Y.; Lee, T. S.; Kobayashi, S.; Khosla, C. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity. Biochemistry 2003, 42, 6588-6595.
-
(2003)
Biochemistry
, vol.42
, pp. 6588-6595
-
-
Tang, Y.1
Lee, T.S.2
Kobayashi, S.3
Khosla, C.4
-
33
-
-
0026539625
-
Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: Role for the acyl carrier protein
-
Khosla, C.; Ebert-Khosla, S.; Hopwood, D. A. Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: Role for the acyl carrier protein. Mol. Microbiol. 1992, 6, 3237-3249.
-
(1992)
Mol. Microbiol
, vol.6
, pp. 3237-3249
-
-
Khosla, C.1
Ebert-Khosla, S.2
Hopwood, D.A.3
-
34
-
-
0027315216
-
Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins
-
Khosla, C.; McDaniel, R.; Ebert-Khosla, S.; Torres, R.; Sherman, D. H.; Bibb, M. J.; Hopwood, D. A. Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins. J. Bacteriol. 1993, 175, 2197-2204.
-
(1993)
J. Bacteriol
, vol.175
, pp. 2197-2204
-
-
Khosla, C.1
McDaniel, R.2
Ebert-Khosla, S.3
Torres, R.4
Sherman, D.H.5
Bibb, M.J.6
Hopwood, D.A.7
-
35
-
-
0026738080
-
Functional replacement of genes for individual polyketide synthase components in Streptomyces coelicolor A3(2) by heterologous genes from a different polyketide pathway
-
Sherman, D. H.; Kim, E. S.; Bibb, M. J.; Hopwood, D. A. Functional replacement of genes for individual polyketide synthase components in Streptomyces coelicolor A3(2) by heterologous genes from a different polyketide pathway. J. Bacteriol. 1992, 174, 6184-6190.
-
(1992)
J. Bacteriol
, vol.174
, pp. 6184-6190
-
-
Sherman, D.H.1
Kim, E.S.2
Bibb, M.J.3
Hopwood, D.A.4
-
36
-
-
28244441235
-
Orthogonal protein interactions in spore pigment producing and antibiotic producing polyketide synthases
-
Lee, T. S.; Khosla, C.; Tang, Y. Orthogonal protein interactions in spore pigment producing and antibiotic producing polyketide synthases. J. Antibiot. (Tokyo) 2005, 58, 663-666.
-
(2005)
J. Antibiot. (Tokyo)
, vol.58
, pp. 663-666
-
-
Lee, T.S.1
Khosla, C.2
Tang, Y.3
-
37
-
-
0030972114
-
Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2)
-
Crump, M. P.; Crosby, J.; Dempsey, C. E.; Parkinson, J. A.; Murray, M.; Hopwood, D. A.; Simpson, T. J. Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2). Biochemistry 1997, 36, 6000-6008.
-
(1997)
Biochemistry
, vol.36
, pp. 6000-6008
-
-
Crump, M.P.1
Crosby, J.2
Dempsey, C.E.3
Parkinson, J.A.4
Murray, M.5
Hopwood, D.A.6
Simpson, T.J.7
-
38
-
-
0037472114
-
Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein
-
Li, Q.; Khosla, C.; Puglisi, J. D.; Liu, C. W. Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein. Biochemistry 2003, 42, 4648-4657.
-
(2003)
Biochemistry
, vol.42
, pp. 4648-4657
-
-
Li, Q.1
Khosla, C.2
Puglisi, J.D.3
Liu, C.W.4
-
39
-
-
0038457084
-
Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus
-
Findlow, S. C.; Winsor, C.; Simpson, T. J.; Crosby, J.; Crump, M. P. Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus. Biochemistry 2003, 42, 8423-8433.
-
(2003)
Biochemistry
, vol.42
, pp. 8423-8433
-
-
Findlow, S.C.1
Winsor, C.2
Simpson, T.J.3
Crosby, J.4
Crump, M.P.5
-
40
-
-
0028242645
-
Engineered biosynthesis of novel polyketides: Dissection of the catalytic specificity of the act ketoreductase
-
Fu, H.; Khosla, S. E.; Hopwood, D. A.; Khosla, C. Engineered biosynthesis of novel polyketides: Dissection of the catalytic specificity of the act ketoreductase. J. Am. Chem. Soc. 1994, 116, 4166-4170.
-
(1994)
J. Am. Chem. Soc
, vol.116
, pp. 4166-4170
-
-
Fu, H.1
Khosla, S.E.2
Hopwood, D.A.3
Khosla, C.4
-
41
-
-
0032511416
-
Engineered biosynthesis of novel polyketides from Streptomyces spore pigment polyketide synthases
-
Tin-Wein, Y.; Shen, Y.; McDaniel, R.; Floss, H. G.; Khosla, C.; Hopwood, D. A.; Moore, B. S. Engineered biosynthesis of novel polyketides from Streptomyces spore pigment polyketide synthases. J. Am. Chem. Soc. 1998, 120, 7749-7759.
-
(1998)
J. Am. Chem. Soc
, vol.120
, pp. 7749-7759
-
-
Tin-Wein, Y.1
Shen, Y.2
McDaniel, R.3
Floss, H.G.4
Khosla, C.5
Hopwood, D.A.6
Moore, B.S.7
-
42
-
-
4644370904
-
The crystal structure of the actlll actinorhodin polyketide reductase: Proposed mechanism for ACP and polyketide binding
-
Hadfield, A. T.; Limpkin, C.; Teartasin, W.; Simpson, T. J.; Crosby, J.; Crump, M. P. The crystal structure of the actlll actinorhodin polyketide reductase: Proposed mechanism for ACP and polyketide binding. Structure 2004, 12, 1865-1875.
-
(2004)
Structure
, vol.12
, pp. 1865-1875
-
-
Hadfield, A.T.1
Limpkin, C.2
Teartasin, W.3
Simpson, T.J.4
Crosby, J.5
Crump, M.P.6
-
43
-
-
8744305865
-
Structural analysis of actinorhodin polyketide ketoreductase: Cofactor binding and substrate specificity
-
Korman, T. P.; Hill, J. A.; Vu, T. N.; Tsai, S. C. Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity. Biochemistry 2004, 43, 14529-14538.
-
(2004)
Biochemistry
, vol.43
, pp. 14529-14538
-
-
Korman, T.P.1
Hill, J.A.2
Vu, T.N.3
Tsai, S.C.4
-
44
-
-
39649122833
-
Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase
-
Korman, T. P.; Tan, Y. H.; Wong, J.; Luo, R.; Tsai, S. C. Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase. Biochemistry 2008, 47, 1837-1847.
-
(2008)
Biochemistry
, vol.47
, pp. 1837-1847
-
-
Korman, T.P.1
Tan, Y.H.2
Wong, J.3
Luo, R.4
Tsai, S.C.5
-
45
-
-
44449157594
-
Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides
-
Ames, B. D.; Korman, T. P.; Zhang, W.; Smith, P.; Vu, T.; Tang, Y.; Tsai, S. C. Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 5349-5354.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 5349-5354
-
-
Ames, B.D.1
Korman, T.P.2
Zhang, W.3
Smith, P.4
Vu, T.5
Tang, Y.6
Tsai, S.C.7
-
46
-
-
33751579141
-
Structural and functional studies on SC01815: Aβ-ketoacyl-acyl carrier protein reductase from Streptomyces coelicolor A3(2)
-
Tang, Y.; Lee, H. Y.; Kim, C. Y.; Mathews, I.; Khosla, C. Structural and functional studies on SC01815: Aβ-ketoacyl-acyl carrier protein reductase from Streptomyces coelicolor A3(2). Biochemistry 2006, 45, 14085-14093.
-
(2006)
Biochemistry
, vol.45
, pp. 14085-14093
-
-
Tang, Y.1
Lee, H.Y.2
Kim, C.Y.3
Mathews, I.4
Khosla, C.5
-
47
-
-
0033609499
-
Purification and properties of the Streptomyces peucetius DpsC β-ketoacyI: Acyl carrier protein synthase III that specifies the propionate-starter unit for type II polyketide biosynthesis
-
Bao, W.; Sheldon, P. J.; Hutchinson, C. R. Purification and properties of the Streptomyces peucetius DpsC β-ketoacyI: acyl carrier protein synthase III that specifies the propionate-starter unit for type II polyketide biosynthesis. Biochemistry 1999, 38, 9752-9757.
-
(1999)
Biochemistry
, vol.38
, pp. 9752-9757
-
-
Bao, W.1
Sheldon, P.J.2
Hutchinson, C.R.3
-
48
-
-
0032766245
-
The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide
-
Bao, W.; Sheldon, P. J.; Wendt-Pienkowski, E.; Hutchinson, C. R. The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide. J. Bacteriol. 1999, 181, 4690-4695.
-
(1999)
J. Bacteriol
, vol.181
, pp. 4690-4695
-
-
Bao, W.1
Sheldon, P.J.2
Wendt-Pienkowski, E.3
Hutchinson, C.R.4
-
49
-
-
0035846645
-
In vitro reconstitution and analysis of the chain initiating enzymes of the R1128 polyketide synthase
-
Meadows, E. S.; Khosla, C. In vitro reconstitution and analysis of the chain initiating enzymes of the R1128 polyketide synthase. Biochemistry 2001, 40, 14855-14861.
-
(2001)
Biochemistry
, vol.40
, pp. 14855-14861
-
-
Meadows, E.S.1
Khosla, C.2
-
50
-
-
0036848668
-
Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway
-
Pan, H.; Tsai, S.; Meadows, E. S.; Miercke, L. J.; Keatinge-Clay, A. T.; O'Connell, J.; Khosla, C.; Stroud, R. M. Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway. Structure 2002, 10, 1559-1568.
-
(2002)
Structure
, vol.10
, pp. 1559-1568
-
-
Pan, H.1
Tsai, S.2
Meadows, E.S.3
Miercke, L.J.4
Keatinge-Clay, A.T.5
O'Connell, J.6
Khosla, C.7
Stroud, R.M.8
-
51
-
-
3242738305
-
The acyltransferase homologue from the initiation module of the R1128 polyketide synthase is an acyl-ACP thioesterase that edits acetyl primer units
-
Tang, Y.; Koppisch, A. T.; Khosla, C. The acyltransferase homologue from the initiation module of the R1128 polyketide synthase is an acyl-ACP thioesterase that edits acetyl primer units. Biochemistry 2004, 43, 9546-9555.
-
(2004)
Biochemistry
, vol.43
, pp. 9546-9555
-
-
Tang, Y.1
Koppisch, A.T.2
Khosla, C.3
-
52
-
-
48249137414
-
Total biosynthesis: In vitro reconstitution of polyketide and nonribosomal peptide pathways
-
Sattely, E. S.; Fischbach, M. A.; Walsh, C. T. Total biosynthesis: In vitro reconstitution of polyketide and nonribosomal peptide pathways. Nat. Prod. Rep. 2008, 25, 757-793.
-
(2008)
Nat. Prod. Rep
, vol.25
, pp. 757-793
-
-
Sattely, E.S.1
Fischbach, M.A.2
Walsh, C.T.3
-
53
-
-
38949083855
-
The chemical versatility of natural-product assembly lines
-
Walsh, C. T. The chemical versatility of natural-product assembly lines. Acc. Chem. Res. 2008, 41, 4-10.
-
(2008)
Acc. Chem. Res
, vol.41
, pp. 4-10
-
-
Walsh, C.T.1
-
54
-
-
0034887171
-
Polyketide biosynthesis: A millennium review
-
Staunton, J.; Weissman, K. J. Polyketide biosynthesis: A millennium review. Nat. Prod. Rep. 2001, 18, 380-416.
-
(2001)
Nat. Prod. Rep
, vol.18
, pp. 380-416
-
-
Staunton, J.1
Weissman, K.J.2
-
55
-
-
0037224423
-
Characterization of benzoyl coenzyme A biosynthesis genes in the enterocin-producing bacterium "Streptomyces maritimus
-
Xiang, L.; Moore, B. S. Characterization of benzoyl coenzyme A biosynthesis genes in the enterocin-producing bacterium "Streptomyces maritimus". J. Bacteriol. 2003, 185, 399-404.
-
(2003)
J. Bacteriol
, vol.185
, pp. 399-404
-
-
Xiang, L.1
Moore, B.S.2
-
56
-
-
32244443360
-
Priming type II polyketide synthases via a type II nonribosomal peptide synthetase mechanism
-
Izumikawa, M.; Cheng, Q.; Moore, B. S. Priming type II polyketide synthases via a type II nonribosomal peptide synthetase mechanism. J. Am. Chem. Soc. 2006, 128, 1428-1429.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 1428-1429
-
-
Izumikawa, M.1
Cheng, Q.2
Moore, B.S.3
-
57
-
-
3343016696
-
The hedamycin locus implicates a novel aromatic PKS priming mechanism
-
Bililign, T.; Hyun, C. G.; Williams, J. S.; Czisny, A. M.; Thorson, J. S. The hedamycin locus implicates a novel aromatic PKS priming mechanism. Chem. Biol. 2004, 11, 959-969.
-
(2004)
Chem. Biol
, vol.11
, pp. 959-969
-
-
Bililign, T.1
Hyun, C.G.2
Williams, J.S.3
Czisny, A.M.4
Thorson, J.S.5
-
58
-
-
85069172328
-
-
3rd ed, Schaechter, M, Ed, Academic Press: San Diego, CA, in press
-
Ridley, C. R.; Khosla, C. In Encyclopedia of Microbiology, 3rd ed.; Schaechter, M., Ed.; Academic Press: San Diego, CA, 2009, in press.
-
(2009)
Encyclopedia of Microbiology
-
-
Ridley, C.R.1
Khosla, C.2
-
59
-
-
0037459418
-
First In vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: Evidence for the mechanism of chain length determination
-
Nicholson, T. P.; Winfield, C.; Westcott, J.; Crosby, J.; Simpson, T. J.; Cox, R. J. First In vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: evidence for the mechanism of chain length determination. Chem. Commun. 2003, 686-687.
-
(2003)
Chem. Commun
, pp. 686-687
-
-
Nicholson, T.P.1
Winfield, C.2
Westcott, J.3
Crosby, J.4
Simpson, T.J.5
Cox, R.J.6
-
60
-
-
0033535067
-
Proof that the ACTVI genetic region of Streptomyces coelicolor A3(2) is involved in stereospecific pyran ring formation in the biosynthesis of actinorhodin
-
Ichinose, K.; Surti, C.; Taguchi, T.; Malpartida, F.; Booker-Milburn, K. I.; Stephenson, G. R.; Ebizuka, Y.; Hopwood, D. A. Proof that the ACTVI genetic region of Streptomyces coelicolor A3(2) is involved in stereospecific pyran ring formation in the biosynthesis of actinorhodin. Bioorg. Med. Chem. Lett. 1999, 9, 395-400.
-
(1999)
Bioorg. Med. Chem. Lett
, vol.9
, pp. 395-400
-
-
Ichinose, K.1
Surti, C.2
Taguchi, T.3
Malpartida, F.4
Booker-Milburn, K.I.5
Stephenson, G.R.6
Ebizuka, Y.7
Hopwood, D.A.8
-
61
-
-
34547651180
-
Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin
-
Mittler, M.; Bechthold, A.; Schulz, G. E. Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin. J. Mol. Biol. 2007, 372, 67-76.
-
(2007)
J. Mol. Biol
, vol.372
, pp. 67-76
-
-
Mittler, M.1
Bechthold, A.2
Schulz, G.E.3
-
62
-
-
0041708004
-
Mutasynthesis of enterocin and wailupemycin analogues
-
Kalaitzis, J. A.; Izumikawa, M.; Xiang, L.; Hertweck, C.; Moore, B. S. Mutasynthesis of enterocin and wailupemycin analogues. J. Am. Chem. Soc. 2003, 125, 9290-9291.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 9290-9291
-
-
Kalaitzis, J.A.1
Izumikawa, M.2
Xiang, L.3
Hertweck, C.4
Moore, B.S.5
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