Resistance to age-dependent thymic atrophy in long-lived mice that are deficient in pregnancy-associated plasma protein A

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 27, 2009, Pages 11252-11257

  Vallejo, Abbe N ^a,b,c,d   Michel, Joshua J ^a,b   Bale, Laurie K ^e   Lemster, Bonnie H ^a,b   Borghesi, Lisa ^a,c   Conover, Cheryl A ^e  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e MAYO CLINIC   (United States)

Author keywords

Aging; Insulin like growth factor; T cells; Thymus

Indexed keywords

CYTOKINE; HERMES ANTIGEN; IMMUNOGLOBULIN; LEUKOSIALIN; PREGNANCY ASSOCIATED PLASMA PROTEIN A; SOMATOMEDIN; T LYMPHOCYTE RECEPTOR;

AGE DISTRIBUTION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; BIOASSAY; BONE MARROW; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GLYCOSYLATION; HOMEOSTASIS; IMMUNOGLOBULIN PRODUCTION; INHIBITION KINETICS; LONGEVITY; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRE T LYMPHOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; THYMUS ATROPHY; WILD TYPE;

AGING; ANIMALS; ATROPHY; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOKINES; IMMUNOGLOBULIN G; IMMUNOLOGIC MEMORY; INSULIN-LIKE GROWTH FACTOR I; KINETICS; LONGEVITY; LYMPHOCYTE ACTIVATION; MICE; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; RECEPTORS, ANTIGEN, T-CELL; STEM CELLS; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; THYMUS GLAND;

CUCURBITA; MUS;

EID: 67650500644     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0807025106     Document Type: Article

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