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Volumn 102, Issue 8, 2003, Pages 2933-2939

IGF-1 down-regulates IFN-γR2 chain surface expression and desensitizes IFN-γ/STAT-1 signaling in human T lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON RECEPTOR; GAMMA INTERFERON RECEPTOR 2; MONOCLONAL ANTIBODY; PHYTOHEMAGGLUTININ; SOMATOMEDIN C; STAT1 PROTEIN; UNCLASSIFIED DRUG;

EID: 0141993007     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-01-0100     Document Type: Article
Times cited : (44)

References (47)
  • 1
    • 0032791044 scopus 로고    scopus 로고
    • Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: A possible role in immune response control
    • Martins G-A, Vieira L-Q, Cunha F-Q, Silva J-S. Gamma interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infect Immun. 1999;67:3864-3871.
    • (1999) Infect Immun , vol.67 , pp. 3864-3871
    • Martins, G.-A.1    Vieira, L.-Q.2    Cunha, F.-Q.3    Silva, J.-S.4
  • 2
    • 0034600788 scopus 로고    scopus 로고
    • Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells
    • Dalton D-K, Haynes L, Chu C-Q, Swain S, Wittmer S. Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J Exp Med. 2000;192:117-122.
    • (2000) J Exp Med , vol.192 , pp. 117-122
    • Dalton, D.-K.1    Haynes, L.2    Chu, C.-Q.3    Swain, S.4    Wittmer, S.5
  • 3
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
    • Chu C-Q, Wittmer D, Dalton D-K. Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J Exp Med. 2000;192:123-128.
    • (2000) J Exp Med , vol.192 , pp. 123-128
    • Chu, C.-Q.1    Wittmer, D.2    Dalton, D.-K.3
  • 4
    • 0031667215 scopus 로고    scopus 로고
    • Apoptotic regulation of T cells and absence of immune deficiency in virus-infected gamma interferon receptor knockout mice
    • Lohman B-L, Welsh R-M. Apoptotic regulation of T cells and absence of immune deficiency in virus-infected gamma interferon receptor knockout mice. J Virol. 1998;72:7815-7821.
    • (1998) J Virol , vol.72 , pp. 7815-7821
    • Lohman, B.-L.1    Welsh, R.-M.2
  • 6
    • 0037037582 scopus 로고    scopus 로고
    • Interferon gamma is required for activation-induced death of T lymphocytes
    • Refaeli Y, Van Parijs L, Alexander S-I, Abbas A-K. Interferon gamma is required for activation-induced death of T lymphocytes. J Exp Med. 2002;196:999-1005.
    • (2002) J Exp Med , vol.196 , pp. 999-1005
    • Refaeli, Y.1    Van Parijs, L.2    Alexander, S.-I.3    Abbas, A.-K.4
  • 7
    • 0025685264 scopus 로고
    • Interferon gamma plays a critical role in induced cell death of effector T cells: A possible third mechanism of self-tolerance
    • Liu Y, Janeway C-A. Interferon gamma plays a critical role in induced cell death of effector T cells: a possible third mechanism of self-tolerance. J Exp Med. 1990;172:1735-1738.
    • (1990) J Exp Med , vol.172 , pp. 1735-1738
    • Liu, Y.1    Janeway, C.-A.2
  • 8
    • 0030240383 scopus 로고    scopus 로고
    • Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha and beta-chains of its receptor
    • Novelli F, Bernabei P, Ozmen L, et al. Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha and beta-chains of its receptor. J Immunol. 1996;157:1935-1943.
    • (1996) J Immunol , vol.157 , pp. 1935-1943
    • Novelli, F.1    Bernabei, P.2    Ozmen, L.3
  • 9
    • 0031179124 scopus 로고    scopus 로고
    • Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones
    • Novelli F, D'Elios M-M, Bernabei P, et al. Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones. J Immunol. 1997;159:206-213.
    • (1997) J Immunol , vol.159 , pp. 206-213
    • Novelli, F.1    D'Elios, M.-M.2    Bernabei, P.3
  • 10
    • 0035066748 scopus 로고    scopus 로고
    • Regulation of interferon-gamma receptor (IFN-gammaR) chains: A peculiar way to rule the life and death of human lymphocytes
    • Bernabei P, Allione A, Rigamonti L, et al. Regulation of interferon-gamma receptor (IFN-gammaR) chains: a peculiar way to rule the life and death of human lymphocytes. Eur Cytokine Netw. 2001;12:6-14.
    • (2001) Eur Cytokine Netw , vol.12 , pp. 6-14
    • Bernabei, P.1    Allione, A.2    Rigamonti, L.3
  • 11
    • 0034176741 scopus 로고    scopus 로고
    • Ligand-independent down-regulation of IFN-gamma receptor 1 following TCR engagement
    • Skrenta H, Yang Y, Pestka S, Fathman C-G. Ligand-independent down-regulation of IFN-gamma receptor 1 following TCR engagement. J Immunol. 2000;164:3506-3511.
    • (2000) J Immunol , vol.164 , pp. 3506-3511
    • Skrenta, H.1    Yang, Y.2    Pestka, S.3    Fathman, C.-G.4
  • 12
    • 0026661047 scopus 로고
    • Distribution of interferon-gamma receptor in human tissues
    • Valente G, Ozmen L, Novelli F, et al. Distribution of interferon-gamma receptor in human tissues. Eur J Immunol. 1992;22:2403-2412.
    • (1992) Eur J Immunol , vol.22 , pp. 2403-2412
    • Valente, G.1    Ozmen, L.2    Novelli, F.3
  • 13
    • 0035216135 scopus 로고    scopus 로고
    • Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death
    • Bernabei P, Coccia E-M, Rigamonti L, et al. Interferon-gamma receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death. J Leukoc Biol. 2001;70:950-960.
    • (2001) J Leukoc Biol , vol.70 , pp. 950-960
    • Bernabei, P.1    Coccia, E.-M.2    Rigamonti, L.3
  • 14
    • 0028972504 scopus 로고
    • Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets
    • Bach E-A, Szabo S-J, Dighe A-S, et al. Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets. Science. 1995;270:1215-1218.
    • (1995) Science , vol.270 , pp. 1215-1218
    • Bach, E.-A.1    Szabo, S.-J.2    Dighe, A.-S.3
  • 15
    • 0029015464 scopus 로고
    • Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells
    • Pernis A, Gupta S, Gollob K-J, et al. Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells. Science. 1995;269:245-247.
    • (1995) Science , vol.269 , pp. 245-247
    • Pernis, A.1    Gupta, S.2    Gollob, K.-J.3
  • 16
    • 0031570388 scopus 로고    scopus 로고
    • Induction of human T helper cell type 1 differentiation results in loss of IFN-gamma receptor beta-chain expression
    • Groux H, Sornasse T, Cottrez F, et al. Induction of human T helper cell type 1 differentiation results in loss of IFN-gamma receptor beta-chain expression. J Immunol. 1997;158:5627-5631.
    • (1997) J Immunol , vol.158 , pp. 5627-5631
    • Groux, H.1    Sornasse, T.2    Cottrez, F.3
  • 17
    • 0033985193 scopus 로고    scopus 로고
    • Surface expression of the IFN-gamma R2 chain is regulated by intracellular trafficking in human T lymphocytes
    • Rigamonti L, Ariotti S, Losana G, et al. Surface expression of the IFN-gamma R2 chain is regulated by intracellular trafficking in human T lymphocytes. J Immunol. 2000;164:201-207.
    • (2000) J Immunol , vol.164 , pp. 201-207
    • Rigamonti, L.1    Ariotti, S.2    Losana, G.3
  • 18
    • 0032169277 scopus 로고    scopus 로고
    • Beta-galactoside-binding protein (beta GBP) alters the cell cycle, up-regulates expression of the alpha- and beta-chains of the IFN-gamma receptor, and triggers IFN-gamma-mediated apoptosis of activated human T lymphocytes
    • Allione A, Wells V, Forni G, Mallucci L, Novelli F. Beta-galactoside-binding protein (beta GBP) alters the cell cycle, up-regulates expression of the alpha- and beta-chains of the IFN-gamma receptor, and triggers IFN-gamma-mediated apoptosis of activated human T lymphocytes. J Immunol. 1998;161:2114-2119.
    • (1998) J Immunol , vol.161 , pp. 2114-2119
    • Allione, A.1    Wells, V.2    Forni, G.3    Mallucci, L.4    Novelli, F.5
  • 19
    • 0032828455 scopus 로고    scopus 로고
    • Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis
    • Allione A, Bernabel P, Bosticardo M, Arlotti S, Forni G, Novelli F. Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis. J Immunol. 1999;163:4182-4191.
    • (1999) J Immunol , vol.163 , pp. 4182-4191
    • Allione, A.1    Bernabel, P.2    Bosticardo, M.3    Arlotti, S.4    Forni, G.5    Novelli, F.6
  • 20
    • 0029863903 scopus 로고    scopus 로고
    • Fas and the art of lymphocyte maintenance
    • Lenardo M-J. Fas and the art of lymphocyte maintenance. J Exp Med. 1996;183:721-724.
    • (1996) J Exp Med , vol.183 , pp. 721-724
    • Lenardo, M.-J.1
  • 21
    • 0029819158 scopus 로고    scopus 로고
    • Prolactin, growth hormone, and insulin-like growth factor-I in the immune system
    • Kooijman R, Hooghe-Peters E-L, Hooghe R. Prolactin, growth hormone, and insulin-like growth factor-I in the immune system. Adv Immunol. 1996;63:377-454.
    • (1996) Adv Immunol , vol.63 , pp. 377-454
    • Kooijman, R.1    Hooghe-Peters, E.-L.2    Hooghe, R.3
  • 22
    • 7144251180 scopus 로고    scopus 로고
    • Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients
    • Nguyen B-Y, Clerici M, Venzon D-J, et al. Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients. AIDS. 1998;12:895-904.
    • (1998) AIDS , vol.12 , pp. 895-904
    • Nguyen, B.-Y.1    Clerici, M.2    Venzon, D.-J.3
  • 23
    • 0034254438 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 promotes cord blood T cell maturation and inhibits its spontaneous and phytohemagglutinin-induced apoptosis through different mechanisms
    • Tu W, Cheung P-T, Lau Y-L. Insulin-like growth factor 1 promotes cord blood T cell maturation and inhibits its spontaneous and phytohemagglutinin-induced apoptosis through different mechanisms. J Immunol. 2000;165:1331-1336.
    • (2000) J Immunol , vol.165 , pp. 1331-1336
    • Tu, W.1    Cheung, P.-T.2    Lau, Y.-L.3
  • 24
    • 0345580185 scopus 로고    scopus 로고
    • IGF-I increases interferon-gamma and IL-6 mRNA expression and protein production in neonatal mononuclear cells
    • Tu W, Cheung P-T, Lau Y-L. IGF-I increases interferon-gamma and IL-6 mRNA expression and protein production in neonatal mononuclear cells. Pediatr Res. 1999;46:748-754.
    • (1999) Pediatr Res , vol.46 , pp. 748-754
    • Tu, W.1    Cheung, P.-T.2    Lau, Y.-L.3
  • 25
    • 0033003249 scopus 로고    scopus 로고
    • Effect of insulin-like growth factor 1 on PHA-stimulated cord blood mononuclear cell telomerase activity
    • Tu W, Zhang D-K, Cheung P-T, Tsao S-W, Lau Y-L. Effect of insulin-like growth factor 1 on PHA-stimulated cord blood mononuclear cell telomerase activity. Br J Haematol. 1999;104:785-794.
    • (1999) Br J Haematol , vol.104 , pp. 785-794
    • Tu, W.1    Zhang, D.-K.2    Cheung, P.-T.3    Tsao, S.-W.4    Lau, Y.-L.5
  • 26
    • 0033994661 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosis
    • Walsh P-T, O'Connor R. The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosis. Eur J Immunol. 2000;30:1010-1018.
    • (2000) Eur J Immunol , vol.30 , pp. 1010-1018
    • Walsh, P.-T.1    O'Connor, R.2
  • 27
    • 0028205312 scopus 로고
    • Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis
    • Novelli F, Di Pierro F, Francia di Celle P, et al. Environmental signals influencing expression of the IFN-gamma receptor on human T cells control whether IFN-gamma promotes proliferation or apoptosis. J Immunol. 1994;152:496-504.
    • (1994) J Immunol , vol.152 , pp. 496-504
    • Novelli, F.1    Di Pierro, F.2    Francia di Celle, P.3
  • 28
    • 0032005607 scopus 로고    scopus 로고
    • Downregulation of insulin-like growth factor-1 receptor (IGF-1R) expression in human T lymphocyte activation
    • Schillaci R, Brocardo M-G, Galeano A, Roldan A. Downregulation of insulin-like growth factor-1 receptor (IGF-1R) expression in human T lymphocyte activation. Cell Immunol. 1998;183:157-161.
    • (1998) Cell Immunol , vol.183 , pp. 157-161
    • Schillaci, R.1    Brocardo, M.-G.2    Galeano, A.3    Roldan, A.4
  • 29
    • 0023038743 scopus 로고
    • Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage
    • McQuillan D-J, Handley C-J, Campbell M-A, Bolis S, Milway V-E, Herington A-C. Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage. Biochem J. 1986;240:423-430.
    • (1986) Biochem J , vol.240 , pp. 423-430
    • McQuillan, D.-J.1    Handley, C.-J.2    Campbell, M.-A.3    Bolis, S.4    Milway, V.-E.5    Herington, A.-C.6
  • 30
    • 0020359313 scopus 로고
    • The high affinity insulin receptor mediates growth stimulation in rat hepatoma cells
    • Massague J, Blinderman L-A, Czech M-P. The high affinity insulin receptor mediates growth stimulation in rat hepatoma cells. J Biol Chem. 1982;257:13958-13963.
    • (1982) J Biol Chem , vol.257 , pp. 13958-13963
    • Massague, J.1    Blinderman, L.-A.2    Czech, M.-P.3
  • 32
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell J-E Jr, Kerr I-M, Stark G-R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 1994;264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell J.-E., Jr.1    Kerr, I.-M.2    Stark, G.-R.3
  • 33
    • 0037103134 scopus 로고    scopus 로고
    • Lipid microdomains are required sites for the selective endocytosis and nuclear translocation of IFN-gamma, its receptor chain IFN-gamma receptor-1, and the phosphorylation and nuclear translocation of STAT1 alpha
    • Subramaniam P-S, Johnson H-M. Lipid microdomains are required sites for the selective endocytosis and nuclear translocation of IFN-gamma, its receptor chain IFN-gamma receptor-1, and the phosphorylation and nuclear translocation of STAT1 alpha. J Immunol. 2002;169:1959-1969.
    • (2002) J Immunol , vol.169 , pp. 1959-1969
    • Subramaniam, P.-S.1    Johnson, H.-M.2
  • 34
    • 0035265834 scopus 로고    scopus 로고
    • Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway
    • Lamaze C, Dujeancourt A, Baba T, Lo C-G, Benmerah A, Dautry-Varsat A. Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway. Mol Cell. 2001;7:661-671.
    • (2001) Mol Cell , vol.7 , pp. 661-671
    • Lamaze, C.1    Dujeancourt, A.2    Baba, T.3    Lo, C.-G.4    Benmerah, A.5    Dautry-Varsat, A.6
  • 35
    • 0026595221 scopus 로고
    • Expression and function of insulin-like growth factor receptors on anti-CD3-activated human T lymphocytes
    • Johnson E-W, Jones L-A, Kozak R-W. Expression and function of insulin-like growth factor receptors on anti-CD3-activated human T lymphocytes. J Immunol. 1992;148:63-71.
    • (1992) J Immunol , vol.148 , pp. 63-71
    • Johnson, E.-W.1    Jones, L.-A.2    Kozak, R.-W.3
  • 38
    • 0036854891 scopus 로고    scopus 로고
    • Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: Regulation by SOCS
    • Hong F, Jaruga B, Kim W-H, et al. Opposing roles of STAT1 and STAT3 in T cell-mediated hepatitis: regulation by SOCS. J Clin Invest. 2002;110:1503-1513.
    • (2002) J Clin Invest , vol.110 , pp. 1503-1513
    • Hong, F.1    Jaruga, B.2    Kim, W.-H.3
  • 39
    • 0033023926 scopus 로고    scopus 로고
    • Lineage-specific activation of STAT3 by interferon-gamma in human neutrophils
    • Caldenhoven E, Buitenhuis M, van Dijk T-B, et al. Lineage-specific activation of STAT3 by interferon-gamma in human neutrophils. J Leukoc Biol. 1999;65:391-396.
    • (1999) J Leukoc Biol , vol.65 , pp. 391-396
    • Caldenhoven, E.1    Buitenhuis, M.2    Van Dijk, T.-B.3
  • 40
    • 0031452335 scopus 로고    scopus 로고
    • Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-γ due to phosphorylation of Stat1 and Stat3
    • Sato T, Selleri C, Young N-S, Maciejewski J-P. Inhibition of interferon regulatory factor-1 expression results in predominance of cell growth stimulatory effects of interferon-γ due to phosphorylation of Stat1 and Stat3. Blood. 1997;90:4749-4758.
    • (1997) Blood , vol.90 , pp. 4749-4758
    • Sato, T.1    Selleri, C.2    Young, N.-S.3    Maciejewski, J.-P.4
  • 41
    • 0028500836 scopus 로고
    • Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors
    • Dighe A-S, Richards E, Old L-J, Schreiber R-D. Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors. Immunity 1994;1:447-456.
    • (1994) Immunity , vol.1 , pp. 447-456
    • Dighe, A.-S.1    Richards, E.2    Old, L.-J.3    Schreiber, R.-D.4
  • 42
    • 0035953308 scopus 로고    scopus 로고
    • IFN-gamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • Shankaran V, Ikeda H, Bruce A-T, et al. IFN-gamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature. 2001;410:1107-1111.
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.-T.3
  • 43
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
    • Kaplan D-H, Shankaran V, Dighe A-S, et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A. 1998;95:7556-7561.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7556-7561
    • Kaplan, D.-H.1    Shankaran, V.2    Dighe, A.-S.3
  • 44
    • 0028890744 scopus 로고
    • The insulin-like growth factor I receptor: A key to tumor growth?
    • Baserga R. The insulin-like growth factor I receptor: a key to tumor growth? Cancer Res. 1995;55:249-252.
    • (1995) Cancer Res , vol.55 , pp. 249-252
    • Baserga, R.1
  • 46
    • 0035863751 scopus 로고    scopus 로고
    • Interferon resistance of cutaneous T-cell lymphoma-derived clonal T-helper 2 cells allows selective viral replication
    • Dummer R, Dobbeling U, Geertsen R, Willers J, Burg G, Pavlovic J. Interferon resistance of cutaneous T-cell lymphoma-derived clonal T-helper 2 cells allows selective viral replication. Blood. 2001;97:523-527.
    • (2001) Blood , vol.97 , pp. 523-527
    • Dummer, R.1    Dobbeling, U.2    Geertsen, R.3    Willers, J.4    Burg, G.5    Pavlovic, J.6


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