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Volumn 125, Issue 3, 2009, Pages 541-547

Mucin-depleted foci show strong activation of inflammatory markers in 1,2-dimethylhydrazine-induced carcinogenesis and are promoted by the inflammatory agent sodium dextran sulfate

Author keywords

Colon carcinogenesis; COX 2; i NOS; Mucin depleted foci; Preneoplastic lesions

Indexed keywords

1,2 DIMETHYLHYDRAZINE; AZOXYMETHANE; CYCLOOXYGENASE 2; DEXTRAN SULFATE; INDUCIBLE NITRIC OXIDE SYNTHASE; MUCIN; RNA;

EID: 67650097007     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24417     Document Type: Article
Times cited : (26)

References (45)
  • 1
    • 0038181338 scopus 로고    scopus 로고
    • Identification of mucin-depleted foci (MDF) in the unsectioned colon of azoxymethane (AOM)-treated rats: Correlation with carcinogenesis
    • Caderni G, Femia AP, Giannini A, Favuzza A, Luceri C, Salvadori M, Dolara P. Identification of mucin-depleted foci (MDF) in the unsectioned colon of azoxymethane (AOM)-treated rats: correlation with carcinogenesis. Cancer Res 2003;63:2388-92.
    • (2003) Cancer Res , vol.63 , pp. 2388-2392
    • Caderni, G.1    Femia, A.P.2    Giannini, A.3    Favuzza, A.4    Luceri, C.5    Salvadori, M.6    Dolara, P.7
  • 3
    • 20444447560 scopus 로고    scopus 로고
    • Mucin-depleted foci have beta-catenin gene mutations, altered expression of its protein, and are dose- and time-dependent in the colon of 1,2-dimethylhydrazine-treated rats
    • Femia AP, Bendinelli B, Giannini A, Salvadori M, Pinzani P, Dolara P, Caderni G. Mucin-depleted foci have beta-catenin gene mutations, altered expression of its protein, and are dose- and time-dependent in the colon of 1,2-dimethylhydrazine-treated rats. Int J Cancer 2005;116:9-15.
    • (2005) Int J Cancer , vol.116 , pp. 9-15
    • Femia, A.P.1    Bendinelli, B.2    Giannini, A.3    Salvadori, M.4    Pinzani, P.5    Dolara, P.6    Caderni, G.7
  • 4
    • 33846680079 scopus 로고    scopus 로고
    • Frequent mutation of Apc gene in rat colon tumors and mucindepleted foci, preneoplastic lesions in experimental colon carcinogenesis
    • Femia AP, Dolara P, Giannini A, Salvadori M, Biggeri A, Caderni G. Frequent mutation of Apc gene in rat colon tumors and mucindepleted foci, preneoplastic lesions in experimental colon carcinogenesis. Cancer Res 2007;67:445-9.
    • (2007) Cancer Res , vol.67 , pp. 445-449
    • Femia, A.P.1    Dolara, P.2    Giannini, A.3    Salvadori, M.4    Biggeri, A.5    Caderni, G.6
  • 5
    • 36749026194 scopus 로고    scopus 로고
    • K-ras mutations and mucin profile in preneoplastic lesions and colon tumors induced in rats by 1,2-dimethylhydrazine
    • Femia AP, Tarquini E, Salvadori M, Ferri S, Giannini A, Dolara P, Caderni G. K-ras mutations and mucin profile in preneoplastic lesions and colon tumors induced in rats by 1,2-dimethylhydrazine. Int J Cancer 2008;122:117-23.
    • (2008) Int J Cancer , vol.122 , pp. 117-123
    • Femia, A.P.1    Tarquini, E.2    Salvadori, M.3    Ferri, S.4    Giannini, A.5    Dolara, P.6    Caderni, G.7
  • 6
    • 3042599473 scopus 로고    scopus 로고
    • Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: The role of inflammation
    • Itzkowitz SH, Yio X. Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol 2004;287:G7-17.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Itzkowitz, S.H.1    Yio, X.2
  • 7
    • 0036138686 scopus 로고    scopus 로고
    • Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared
    • Rhodes JM, Campbell BJ. Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared. Trends Mol Med 2002;8:10-6.
    • (2002) Trends Mol Med , vol.8 , pp. 10-16
    • Rhodes, J.M.1    Campbell, B.J.2
  • 8
    • 0029913633 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors
    • DuBois RN, Radhika A, Reddy BS, Entingh AJ. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology 1996;110:1259-62.
    • (1996) Gastroenterology , vol.110 , pp. 1259-1262
    • DuBois, R.N.1    Radhika, A.2    Reddy, B.S.3    Entingh, A.J.4
  • 9
    • 0037138743 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues
    • Thun MJ, Henley SJ, Patrono C. Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues. J Natl Cancer Inst 2002;94:252-66.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 252-266
    • Thun, M.J.1    Henley, S.J.2    Patrono, C.3
  • 12
    • 28844506365 scopus 로고    scopus 로고
    • Mutant KRAS in aberrant crypt foci (ACF): Initiation of colorectal cancer?
    • Pretlow TP, Pretlow TG. Mutant KRAS in aberrant crypt foci (ACF): initiation of colorectal cancer? Biochim Biophys Acta 2005;1756:83-96.
    • (2005) Biochim Biophys Acta , vol.1756 , pp. 83-96
    • Pretlow, T.P.1    Pretlow, T.G.2
  • 13
    • 34548162712 scopus 로고    scopus 로고
    • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammationdriven tumor progression
    • Neufert C, Becker C, Neurath MF. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammationdriven tumor progression. Nat Protocols 2007;2:1998-2004.
    • (2007) Nat Protocols , vol.2 , pp. 1998-2004
    • Neufert, C.1    Becker, C.2    Neurath, M.F.3
  • 14
    • 0344237231 scopus 로고    scopus 로고
    • A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
    • Tanaka T, Kohno H, Suzuki R, Yamada Y, Sugie S, Mori H. A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci 2003;94:965-73.
    • (2003) Cancer Sci , vol.94 , pp. 965-973
    • Tanaka, T.1    Kohno, H.2    Suzuki, R.3    Yamada, Y.4    Sugie, S.5    Mori, H.6
  • 15
    • 5044228671 scopus 로고    scopus 로고
    • Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate
    • Suzuki R, Kohno H, Sugie S, Tanaka T. Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate. Cancer Sci 2004;95:721-7.
    • (2004) Cancer Sci , vol.95 , pp. 721-727
    • Suzuki, R.1    Kohno, H.2    Sugie, S.3    Tanaka, T.4
  • 16
    • 33646108576 scopus 로고    scopus 로고
    • Distribution of preneoplastic lesions and tumors, and beta-catenin gene mutations in colon carcinomas induced by 1,2-dimethylhydrazine plus dextran sulfate sodium
    • Kinjo T, Suzui M, Morioka T, Nabandith V, Inamine M, Kaneshiro T, Arakaki J, Nishimaki T, Yoshimi N. Distribution of preneoplastic lesions and tumors, and beta-catenin gene mutations in colon carcinomas induced by 1,2-dimethylhydrazine plus dextran sulfate sodium. Exp Clin Cancer Res 2006;25:89-95.
    • (2006) Exp Clin Cancer Res , vol.25 , pp. 89-95
    • Kinjo, T.1    Suzui, M.2    Morioka, T.3    Nabandith, V.4    Inamine, M.5    Kaneshiro, T.6    Arakaki, J.7    Nishimaki, T.8    Yoshimi, N.9
  • 17
    • 34247367946 scopus 로고    scopus 로고
    • Mucin-depleted foci are modulated by dietary treatments and show deregulation of proliferative activity in carcinogen-treated rodents
    • Femia AP, Caderni G, Bottini C, Salvadori M, Dolara P, Tessitore L. Mucin-depleted foci are modulated by dietary treatments and show deregulation of proliferative activity in carcinogen-treated rodents. Int J Cancer 2007;120:2301-5.
    • (2007) Int J Cancer , vol.120 , pp. 2301-2305
    • Femia, A.P.1    Caderni, G.2    Bottini, C.3    Salvadori, M.4    Dolara, P.5    Tessitore, L.6
  • 18
    • 0036270040 scopus 로고    scopus 로고
    • Red wine and black tea polyphenols modulate the expression of cycloxygenase-2,inducible nitric oxide synthase and glutathione-related enzymes in azoxymethaneinduced F344 rat colon tumors
    • Luceri C, Caderni G, Sanna A, Dolara P. Red wine and black tea polyphenols modulate the expression of cycloxygenase-2,inducible nitric oxide synthase and glutathione-related enzymes in azoxymethaneinduced F344 rat colon tumors. J Nutr 2002;132:1376-9.
    • (2002) J Nutr , vol.132 , pp. 1376-1379
    • Luceri, C.1    Caderni, G.2    Sanna, A.3    Dolara, P.4
  • 19
    • 1242330441 scopus 로고    scopus 로고
    • Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis
    • Femia AP, Dolara P, Caderni G. Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis. Carcinogenesis 2004;25:277-81.
    • (2004) Carcinogenesis , vol.25 , pp. 277-281
    • Femia, A.P.1    Dolara, P.2    Caderni, G.3
  • 20
    • 0023629080 scopus 로고
    • Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings
    • Bird RP. Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 1987;37:147-51.
    • (1987) Cancer Lett , vol.37 , pp. 147-151
    • Bird, R.P.1
  • 21
    • 0033924401 scopus 로고    scopus 로고
    • Altered expression of beta-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis
    • Takahashi M, Mutoh M, Kawamori T, Sugimura T, Wakabayashi K. Altered expression of beta-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis. Carcinogenesis 2000;21:1319-27.
    • (2000) Carcinogenesis , vol.21 , pp. 1319-1327
    • Takahashi, M.1    Mutoh, M.2    Kawamori, T.3    Sugimura, T.4    Wakabayashi, K.5
  • 24
    • 0036441901 scopus 로고    scopus 로고
    • Most effective colon cancer chemopreventive agents in rats: A systematic review of aberrant crypt foci and tumor data, ranked by potency
    • Corpet DE, Tach́e S. Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency. Nutr Cancer 2002;43:1-21.
    • (2002) Nutr Cancer , vol.43 , pp. 1-21
    • Corpet, D.E.1    Tach́e, S.2
  • 25
    • 0032833473 scopus 로고    scopus 로고
    • High expression of cyclooxygenase-2 in macrophages of human colonic adenoma
    • Bamba H, Ota S, Kato A, Adachi A, Itoyama S, Matsuzaki F. High expression of cyclooxygenase-2 in macrophages of human colonic adenoma. Int J Cancer 1999;83:470-5.
    • (1999) Int J Cancer , vol.83 , pp. 470-475
    • Bamba, H.1    Ota, S.2    Kato, A.3    Adachi, A.4    Itoyama, S.5    Matsuzaki, F.6
  • 26
    • 33745676331 scopus 로고    scopus 로고
    • Increased protein expression of both inducible nitric oxide synthase and cyclooxygenase-2 in human colon cancers
    • Ohta T, Takahashi M, Ochiai A. Increased protein expression of both inducible nitric oxide synthase and cyclooxygenase-2 in human colon cancers. Cancer Lett 2005;239:246-53.
    • (2005) Cancer Lett , vol.239 , pp. 246-253
    • Ohta, T.1    Takahashi, M.2    Ochiai, A.3
  • 27
    • 0029794742 scopus 로고    scopus 로고
    • Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis
    • Reddy BS, Rao CV, Seibert K. Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis. Cancer Res 1996;56:4566-9.
    • (1996) Cancer Res , vol.56 , pp. 4566-4569
    • Reddy, B.S.1    Rao, C.V.2    Seibert, K.3
  • 28
    • 0032006784 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
    • Kawamori T, Rao CV, Seibert K, Reddy BS. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res 1998;58:409-12.
    • (1998) Cancer Res , vol.58 , pp. 409-412
    • Kawamori, T.1    Rao, C.V.2    Seibert, K.3    Reddy, B.S.4
  • 29
    • 5144230475 scopus 로고    scopus 로고
    • Nitric oxide signaling in colon cancer chemoprevention
    • Rao CV. Nitric oxide signaling in colon cancer chemoprevention. Mutat Res 2004;555:107-19.
    • (2004) Mutat Res , vol.555 , pp. 107-119
    • Rao, C.V.1
  • 30
    • 2942655096 scopus 로고    scopus 로고
    • Effects of adlay on azoxymethaneinduced colon carcinogenesis in rats
    • Shih CK, Chiang W, Kuo ML. Effects of adlay on azoxymethaneinduced colon carcinogenesis in rats. Food Chem Toxicol 2004;42:1339-47.
    • (2004) Food Chem Toxicol , vol.42 , pp. 1339-1347
    • Shih, C.K.1    Chiang, W.2    Kuo, M.L.3
  • 31
    • 57249113909 scopus 로고    scopus 로고
    • Sporadic aberrant crypt foci are not a surrogate endpoint for colorectal adenoma prevention
    • Lance P, Hamilton SR. Sporadic aberrant crypt foci are not a surrogate endpoint for colorectal adenoma prevention. Cancer Prev Res 2008;1:4-8.
    • (2008) Cancer Prev Res , vol.1 , pp. 4-8
    • Lance, P.1    Hamilton, S.R.2
  • 38
    • 0036046176 scopus 로고    scopus 로고
    • The role of cyclooxygenase-2 (COX-2) in two different morphological stages of intestinal polyps in APC(Delta474) knockout mice
    • Sunayama K, Konno H, Nakamura T, Kashiwabara H, Shoji T, Tsuneyoshi T, Nakamura S. The role of cyclooxygenase-2 (COX-2) in two different morphological stages of intestinal polyps in APC(Delta474) knockout mice. Carcinogenesis 2002;23:1351-9.
    • (2002) Carcinogenesis , vol.23 , pp. 1351-1359
    • Sunayama, K.1    Konno, H.2    Nakamura, T.3    Kashiwabara, H.4    Shoji, T.5    Tsuneyoshi, T.6    Nakamura, S.7
  • 39
    • 0035863405 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase (iNOS) is expressed similarly in multiple aberrant crypt foci, colorectal tumors from the same patients
    • Hao XP, Pretlow TG, Rao JS, Pretlow TP. Inducible nitric oxide synthase (iNOS) is expressed similarly in multiple aberrant crypt foci, colorectal tumors from the same patients. Cancer Res 2001;61:419-22.
    • (2001) Cancer Res , vol.61 , pp. 419-422
    • Hao, X.P.1    Pretlow, T.G.2    Rao, J.S.3    Pretlow, T.P.4
  • 43
    • 33845736892 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and colorectal cancer chemoprevention: The beta-catenin connection
    • Castellone MD, Teramoto H, Gutkind JS. Cyclooxygenase-2 and colorectal cancer chemoprevention: the beta-catenin connection. Cancer Res 2006;66:1085-8.
    • (2006) Cancer Res , vol.66 , pp. 1085-1088
    • Castellone, M.D.1    Teramoto, H.2    Gutkind, J.S.3
  • 44
    • 40449084279 scopus 로고    scopus 로고
    • Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats
    • Arikawa AY, Gallaher DD. Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats. J Nutr 2008;138:526-32.
    • (2008) J Nutr , vol.138 , pp. 526-532
    • Arikawa, A.Y.1    Gallaher, D.D.2
  • 45
    • 51249122080 scopus 로고    scopus 로고
    • Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium
    • Pierre F, Santarelli R, Tach́e S, Gueraud F, Corpet DE. Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium. Br J Nutr 2008;99:1000-6.
    • (2008) Br J Nutr , vol.99 , pp. 1000-1006
    • Pierre, F.1    Santarelli, R.2    Tach́e, S.3    Gueraud, F.4    Corpet, D.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.