Identification of mucin depleted foci in the human colon

Cancer Prevention Research

Volumn 1, Issue 7, 2008, Pages 562-567

  Femia, Angelo Pietro ^a   Giannini, Augusto ^b   Fazi, Marilena ^a   Tarquini, Elena ^a   Salvadori, Maddalena ^a   Roncucci, Luca ^c   Tonelli, Francesco ^a   Dolara, Piero ^a   Caderni, Giovanna ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b General Hospital of Prato   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MUCIN;

ADENOCARCINOMA; ADULT; ARTICLE; COLON POLYPOSIS; COLON TUMOR; FEMALE; HUMAN; MALE; METABOLISM; PATHOLOGY; PRECANCER;

ADENOCARCINOMA; ADENOMATOUS POLYPOSIS COLI; ADULT; COLONIC NEOPLASMS; FEMALE; HUMANS; MALE; MUCINS; PRECANCEROUS CONDITIONS;

EID: 62349118260     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-08-0125     Document Type: Article

References (40)

1. Bird RP. Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 1987; 37:147-51.
2. Stopera SA, Davie JR, Bird RP. Colonic aberrant crypt foci are associated with increased expression of c-fos: the possible role of modified c-fos expression in preneoplastic lesions in colon cancer. Carcinogenesis 1992;13:573-8.
3. Stopera SA, Murphy LC, Bird RP. Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesions of experimental colon cancer. Carcinogenesis 1992;13:2081-5.
4. McLellan EA, Bird RP. Aberrant crypts: potential preneoplastic lesions in the murine colon. Cancer Res 1988;48:6187-92.
5. Pretlow TP, Barrow BJ, Ashton WS, et al. Aberrant crypts: putative preneoplastic foci in human colonic mucosa. Cancer Res 1991;51:1564-7.
6. Roncucci L, Stamp D, Medline A, Cullen JB, Bruce WR. Identification and quantification of aberrant crypt foci and microadenomas in the human colon. Hum Pathol 1991;22:287-94.
7. Corpet DE, Taché S. Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency. Nutr Cancer 2002;43:1-21.
8. Pretlow TP, Pretlow TG. Mutant KRAS in aberrant crypt foci (ACF): initiation of colorectal cancer? Biochim Biophys Acta 2005;1756:83-96.
9. Zheng Y, Kramer PM, Lubet RA, Steele VE, Kelloff GJ, Pereira MA. Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci. Carcinogenesis 1999;20:255-60.
10. Shih CK, Chiang W, Kuo ML. Effects of adlay on azoxymethane-induced colon carcinogenesis in rats. Food Chem Toxicol 2004;42:1339-47.
11. Papanikolaou A, Wang QS, Papanikolaou D, Whiteley HE, Rosenberg DW. Sequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethaneinduced colon carcinogenesis. Carcinogenesis 2000;21:1567-72.
12. Lance P, Hamilton SR. Sporadic aberrant crypt foci are not a surrogate endpoint for colorectal adenoma prevention. Cancer Prev Res 2008;1:4-8.
13. Stevens RG, Pretlow TP, Hurlstone DP, Giardina C, Rosenberg DW. Comment re: "Sporadic Aberrant Crypt Foci Are Not a Surrogate Endpoint for Colorectal Adenoma Prevention" and "Aberrant Crypt Foci in the Adenoma Prevention with Celecoxib Trial". Cancer Prev Res 2008;1:215-6.
14. Lance P, Hamilton SR. Comment re: "Sporadic Aberrant Crypt Foci Are Not a Surrogate Endpoint for Colorectal Adenoma Prevention" and "Aberrant Crypt Foci in the Adenoma Prevention with Celecoxib Trial". Cancer Prev Res 2008;1:216.
15. Ann G, Zauber AG, Bertagnolli MM, for the APC Trial Investigators. Comment re: "Sporadic Aberrant Crypt Foci Are Not a Surrogate Endpoint for Colorectal Adenoma Prevention" and "Aberrant Crypt Foci in the Adenoma Prevention with Celecoxib Trial". Cancer Prev Res 2008;1:216.
16. Caderni G, Femia AP, Giannini A, et al. Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res 2003;63:2388-92.
17. Corpet DE, Pierre F. How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men. Eur J Cancer 2005;41:1911-22.
18. Femia AP, Dolara P, Caderni G. Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis. Carcinogenesis 2004;25:277-81.
19. Femia AP, Bendinelli B, Giannini A, et al. Mucindepleted foci have β-catenin gene mutations, altered expression of its protein, and are dose- and time-dependent in the colon of 1,2-dimethylhydrazine- treated rats. Int J Cancer 2005;116:9-15.
20. Arikawa AY, Gallaher DD. Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats. J Nutr 2008;138: 526-32.
21. Pierre F, Santarelli R, Taché S, Guéraud F, Corpet DE. Beef meat promotion of dimethylhydrazineinduced colorectal carcinogenesis biomarkers is suppressed by dietary calcium. Br J Nutr 2008;99: 1000-6.
22. Femia AP, Dolara P, Giannini A, et al. Frequent mutation of Apc gene in rat colon tumors and mucin- depleted foci, preneoplastic lesions in experimental colon carcinogenesis. Cancer Res 2007; 67:445-9.
23. Jass JR. Familial colorectal cancer: pathology and molecular characteristics. Lancet Oncol 2000; 1:220-6.
24. Rex DK, Kahi CJ, Levin B, et al. Guidelines for colonoscopy surveillance after cancer resection: a consensus update by the American Cancer Society and the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology 2006;130:1865-71.
25. Day DW, Jass JR, Price AB, et al. Morson and Dawson's gastrointestinal pathology. Oxford: Blackwell Publishing; 2003. p. 553-66.
26. Hamilton SR, Vogelstein B, Kudo S, et al. Carcinoma of the colon and rectum. In: Hamilton SR, Aaltonen LA, editors. WHO classification of tumours: pathology and genetics of tumours of the digestive system. Lyon: IARC Press; 2000. Q5 p. 111-3.
27. Konishi F, Morson BC. Pathology of colorectal adenomas. J Clin Pathol 1982;35:830-41.
28. Di Gregorio C, Losi L, Fante R, et al. Histology of aberrant crypt foci in the human colon. Histopathology 1997;30:328-34.
29. Takayama T, Katsuki S, Takahashi Y, et al. Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med 1998;339:1277-84.
30. Cho NL, Redston M, Zauber AG, et al. Aberrant crypt foci in the adenoma prevention with celecoxib trial. Cancer Prev Res 2008;1:21-31.
31. Nakamura S, Kino I. Morphogenesis of minute adenomas in familial polyposis coli. J Natl Cancer Inst 1984;73:41-9.
32. Gupta AK, Pretlow TP, Schoen RE. Aberrant crypt foci: what we know and what we need to know. Clin Gastroenterol Hepatol 2007;5:526-33.
33. Suzuki H, Watkins DN, Jair KW, et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004;36:417-22.
34. Rosenberg DW, Yang S, Pleau DC, et al. Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans. Cancer Res 2007;67:3551-4.
35. Jen J, Powell SM, Papadopoulos N, et al. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994;54:5523-6.
36. Ochiai M, Watanabe M, Nakanishi M, Taguchi A, Sugimura T, Nakagama H. Differential staining of dysplastic aberrant crypt foci in the colon facilitates prediction of carcinogenic potentials of chemicals in rats. Cancer Lett 2005;220:67-74.
37. Roncucci L, Pedroni M, Vaccina F, Benatti P, Marzona L, De Pol A. Aberrant crypt foci in colorectal carcinogenesis. Cell Crypt Dynamics Cell Prolif 2000;33:1-18.
38. Nucci MR, Robinson CR, Longo P, Campbell P, Hamilton SR. Phenotypic and genotypic characteristics of aberrant crypt foci in human colorectal mucosa. Hum Pathol 1997;28:1396-407.
39. Shpitz B, Klein E, Buklan G, et al. Suppressive effect of aspirin on aberrant crypt foci in patients with colorectal cancer. Gut 2003;52:1598-601.
40. Bouzourene H, Chaubert P, Seelentag W, Bosman FT, Saraga E. Aberrant crypt foci in patients with neoplastic and nonneoplastic colonic disease. Hum Pathol 1999;30:66-71.