메뉴 건너뛰기




Volumn 122, Issue 1, 2008, Pages 117-123

K-ras mutations and mucin profile in preneoplastic lesions and colon tumors induced in rats by 1,2-dimethylhydrazine

Author keywords

ACF; Colon carcinogenesis; K ras; MDF; Mucins

Indexed keywords

1,2 DIMETHYLHYDRAZINE; APC PROTEIN; BIOLOGICAL MARKER; INTESTINAL TREFOIL FACTOR; K RAS PROTEIN; MUCIN;

EID: 36749026194     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23065     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 0023629080 scopus 로고
    • Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings
    • Bird RP. Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 1987;37:147-51.
    • (1987) Cancer Lett , vol.37 , pp. 147-151
    • Bird, R.P.1
  • 2
    • 0034235011 scopus 로고    scopus 로고
    • Frequent β-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis
    • Yamada Y, Yoshimi N, Hirose Y, Kawabata K, Matsunaga K, Shimizu M, Hara A, Mori H. Frequent β-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis. Cancer Res 2000;60:3323-7.
    • (2000) Cancer Res , vol.60 , pp. 3323-3327
    • Yamada, Y.1    Yoshimi, N.2    Hirose, Y.3    Kawabata, K.4    Matsunaga, K.5    Shimizu, M.6    Hara, A.7    Mori, H.8
  • 3
    • 0034121175 scopus 로고    scopus 로고
    • Identification and quantification of aberrant crypt foci in the colon of Min mice - a murine model of familial adenomatous polyposis
    • Paulsen JE, Namork E, Steffensen IL, Eide TJ, Alexander J. Identification and quantification of aberrant crypt foci in the colon of Min mice - a murine model of familial adenomatous polyposis. Scand J Gastroenterol 2000;35:534-9.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 534-539
    • Paulsen, J.E.1    Namork, E.2    Steffensen, I.L.3    Eide, T.J.4    Alexander, J.5
  • 4
    • 0038181338 scopus 로고    scopus 로고
    • Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: Correlation with carcinogenesis
    • Caderni G, Femia AP, Giannini A, Favuzza A, Luceri C, Salvadori M, Dolara P. Identification of mucin-depleted foci in the unsectioned colon of azoxymethane-treated rats: correlation with carcinogenesis. Cancer Res 2003;63:2388-92.
    • (2003) Cancer Res , vol.63 , pp. 2388-2392
    • Caderni, G.1    Femia, A.P.2    Giannini, A.3    Favuzza, A.4    Luceri, C.5    Salvadori, M.6    Dolara, P.7
  • 5
    • 1242330441 scopus 로고    scopus 로고
    • Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis
    • Femia AP, Dolara P, Caderni G. Mucin-depleted foci (MDF) in the colon of rats treated with azoxymethane (AOM) are useful biomarkers for colon carcinogenesis. Carcinogenesis 2004;25:277-81.
    • (2004) Carcinogenesis , vol.25 , pp. 277-281
    • Femia, A.P.1    Dolara, P.2    Caderni, G.3
  • 6
    • 20444447560 scopus 로고    scopus 로고
    • Mucin-depleted foci have β-catenin gene mutations, altered expression of its protein, and are dose- and time-dependent in the colon of 1,2-dimethylhydrazine-treated rats
    • Femia AP, Bendinelli B, Giannini A, Salvadori M, Pinzani P, Dolara P, Caderni G. Mucin-depleted foci have β-catenin gene mutations, altered expression of its protein, and are dose- and time-dependent in the colon of 1,2-dimethylhydrazine-treated rats. Int J Cancer 2005;116:9-15.
    • (2005) Int J Cancer , vol.116 , pp. 9-15
    • Femia, A.P.1    Bendinelli, B.2    Giannini, A.3    Salvadori, M.4    Pinzani, P.5    Dolara, P.6    Caderni, G.7
  • 7
    • 33846680079 scopus 로고    scopus 로고
    • Frequent mutation of Ape gene in rat colon tumors and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis
    • Femia AP, Dolara P, Giannini A, Salvadori M, Biggeri A, Caderni G. Frequent mutation of Ape gene in rat colon tumors and mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis. Cancer Res 2007;67:445-9.
    • (2007) Cancer Res , vol.67 , pp. 445-449
    • Femia, A.P.1    Dolara, P.2    Giannini, A.3    Salvadori, M.4    Biggeri, A.5    Caderni, G.6
  • 8
    • 28844506365 scopus 로고    scopus 로고
    • Mutant KRAS in aberrant crypt foci (ACF): Initiation of colorectal cancer?
    • Pretlow TP, Pretlow TG. Mutant KRAS in aberrant crypt foci (ACF): initiation of colorectal cancer? Biochim Biophys Acta 2005;1756:83-96.
    • (2005) Biochim Biophys Acta , vol.1756 , pp. 83-96
    • Pretlow, T.P.1    Pretlow, T.G.2
  • 11
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 13
    • 0033924401 scopus 로고    scopus 로고
    • Altered expression of β-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis
    • Takahashi M, Mutoh M, Kawamori T, Sugimura T, Wakabayashi K. Altered expression of β-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis. Carcinogenesis 2000;21:1319-27.
    • (2000) Carcinogenesis , vol.21 , pp. 1319-1327
    • Takahashi, M.1    Mutoh, M.2    Kawamori, T.3    Sugimura, T.4    Wakabayashi, K.5
  • 14
    • 0026480765 scopus 로고
    • Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: Earliest recognizable precursor lesions of experimental colon cancer
    • Stopera SA, Murphy LC, Bird RP. Evidence for a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesions of experimental colon cancer. Carcinogenesis 1992;13:2081-5.
    • (1992) Carcinogenesis , vol.13 , pp. 2081-2085
    • Stopera, S.A.1    Murphy, L.C.2    Bird, R.P.3
  • 15
    • 0027426123 scopus 로고
    • K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis
    • Vivona AA, Shpitz B, Medline A, Bruce WR, Hay K, Ward MA, Stern HS, Gallinger S. K-ras mutations in aberrant crypt foci, adenomas and adenocarcinomas during azoxymethane-induced colon carcinogenesis. Carcinogenesis 1993;14:1777-81.
    • (1993) Carcinogenesis , vol.14 , pp. 1777-1781
    • Vivona, A.A.1    Shpitz, B.2    Medline, A.3    Bruce, W.R.4    Hay, K.5    Ward, M.A.6    Stern, H.S.7    Gallinger, S.8
  • 19
    • 0016200769 scopus 로고
    • Abnormal patterns of mucus secretion in apparently normal mucosa of large intestine with carcinoma
    • Filipe MI, Branfoot AC. Abnormal patterns of mucus secretion in apparently normal mucosa of large intestine with carcinoma. Cancer 1974;34:282-90.
    • (1974) Cancer , vol.34 , pp. 282-290
    • Filipe, M.I.1    Branfoot, A.C.2
  • 20
    • 0016696719 scopus 로고
    • Mucous secretion in rat colonic mucosa during carcinogenesis induced by dimethylhydrazine. A morphological and histochemical study
    • Filipe MI. Mucous secretion in rat colonic mucosa during carcinogenesis induced by dimethylhydrazine. A morphological and histochemical study. Br J Cancer 1975;32:60-77.
    • (1975) Br J Cancer , vol.32 , pp. 60-77
    • Filipe, M.I.1
  • 21
    • 33846282337 scopus 로고    scopus 로고
    • Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon
    • Mizoshita T, Tsukamoto T, Inada KI, Hirano N, Tajika M, Nakamura T, Ban H, Tatematsu M. Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon. Histol Histopathol 2007;22:251-60.
    • (2007) Histol Histopathol , vol.22 , pp. 251-260
    • Mizoshita, T.1    Tsukamoto, T.2    Inada, K.I.3    Hirano, N.4    Tajika, M.5    Nakamura, T.6    Ban, H.7    Tatematsu, M.8
  • 22
    • 0020679340 scopus 로고
    • Early oncofetal antigenic modifications during rat colonic carcinogenesis
    • Decaens C, Bara J, Rosa B, Daher N, Burtin P. Early oncofetal antigenic modifications during rat colonic carcinogenesis. Cancer Res 1983;43:355-62.
    • (1983) Cancer Res , vol.43 , pp. 355-362
    • Decaens, C.1    Bara, J.2    Rosa, B.3    Daher, N.4    Burtin, P.5
  • 23
    • 0345689551 scopus 로고    scopus 로고
    • Abnormal expression of gastric mucin in human and rat aberrant crypt foci during colon carcinogenesis
    • Bara J, Forgue-Lafitte ME, Maurin N, Flejou JF, Zimber A. Abnormal expression of gastric mucin in human and rat aberrant crypt foci during colon carcinogenesis. Tumour Biol 2003;24:109-15.
    • (2003) Tumour Biol , vol.24 , pp. 109-115
    • Bara, J.1    Forgue-Lafitte, M.E.2    Maurin, N.3    Flejou, J.F.4    Zimber, A.5
  • 25
    • 34247367946 scopus 로고    scopus 로고
    • Mucin-depleted foci are modulated by dietary treatments and show deregulation of proliferative activity in carcinogen-treated rodents
    • Femia AP, Caderni G, Bottini C, Salvadori M, Dolara P, Tessitore L. Mucin-depleted foci are modulated by dietary treatments and show deregulation of proliferative activity in carcinogen-treated rodents. Int J Cancer 2007;120:2301-5.
    • (2007) Int J Cancer , vol.120 , pp. 2301-2305
    • Femia, A.P.1    Caderni, G.2    Bottini, C.3    Salvadori, M.4    Dolara, P.5    Tessitore, L.6
  • 26
    • 0036849544 scopus 로고    scopus 로고
    • Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats
    • Femia AP, Luceri C, Dolara P, Giannini A, Biggeri A, Salvadori M, Clune Y, Collins KJ, Paglierani M, Caderni G. Antitumorigenic activity of the prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis on azoxymethane-induced colon carcinogenesis in rats. Carcinogenesis 2002;23:1953-60.
    • (2002) Carcinogenesis , vol.23 , pp. 1953-1960
    • Femia, A.P.1    Luceri, C.2    Dolara, P.3    Giannini, A.4    Biggeri, A.5    Salvadori, M.6    Clune, Y.7    Collins, K.J.8    Paglierani, M.9    Caderni, G.10
  • 27
    • 9144249036 scopus 로고    scopus 로고
    • Histological and immunohistochemical observations of mucin-depleted foci (MDF) stained with Alcian blue, in rat colon carcinogenesis induced with 1,2-dimethylhydrazine dihydrochloride
    • Yoshimi N, Morioka T, Kinjo T, Inamine M, Kaneshiro T, Shimizu T, Suzui M, Yamada Y, Mori H. Histological and immunohistochemical observations of mucin-depleted foci (MDF) stained with Alcian blue, in rat colon carcinogenesis induced with 1,2-dimethylhydrazine dihydrochloride. Cancer Sci 2004;95:792-7.
    • (2004) Cancer Sci , vol.95 , pp. 792-797
    • Yoshimi, N.1    Morioka, T.2    Kinjo, T.3    Inamine, M.4    Kaneshiro, T.5    Shimizu, T.6    Suzui, M.7    Yamada, Y.8    Mori, H.9
  • 28
    • 0035099133 scopus 로고    scopus 로고
    • Differences in carcinogenesis by the length of carcinogen exposure period in rat colon
    • Endo T, Ookawa K, Tanaka M, Nakaji S, Tsuchida S, Sugawara K. Differences in carcinogenesis by the length of carcinogen exposure period in rat colon. Dig Dis Sci 2001;46:109-17.
    • (2001) Dig Dis Sci , vol.46 , pp. 109-117
    • Endo, T.1    Ookawa, K.2    Tanaka, M.3    Nakaji, S.4    Tsuchida, S.5    Sugawara, K.6
  • 29
    • 0033035378 scopus 로고    scopus 로고
    • The relationship between 1,2-dimethylhydrazine dose and the induction of colon tumours: Tumour development in female SWR mice does not require a K-ras mutational event
    • Jackson PE, Cooper DP, O'Connor PJ, Povey AC. The relationship between 1,2-dimethylhydrazine dose and the induction of colon tumours: tumour development in female SWR mice does not require a K-ras mutational event. Carcinogenesis 1999;20:509-13.
    • (1999) Carcinogenesis , vol.20 , pp. 509-513
    • Jackson, P.E.1    Cooper, D.P.2    O'Connor, P.J.3    Povey, A.C.4
  • 30
    • 0028299177 scopus 로고
    • Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet
    • Shivapurkar N, Tang Z, Ferreira A, Nasim S, Garett C, Alabaster O. Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane in Fischer-344 rats on high-risk diet. Carcinogenesis 1994;15:775-8.
    • (1994) Carcinogenesis , vol.15 , pp. 775-778
    • Shivapurkar, N.1    Tang, Z.2    Ferreira, A.3    Nasim, S.4    Garett, C.5    Alabaster, O.6
  • 31
    • 0030849321 scopus 로고    scopus 로고
    • Assessment of mutations in Ki-ras and p53 in colon cancers from azoxymethane- and dimethylhydrazine- treated rats
    • Erdman SH, Wu HD, Hixson LJ, Ahnen DJ, Gerner EW. Assessment of mutations in Ki-ras and p53 in colon cancers from azoxymethane- and dimethylhydrazine- treated rats. Mol Carcinog 1997;19:137-44.
    • (1997) Mol Carcinog , vol.19 , pp. 137-144
    • Erdman, S.H.1    Wu, H.D.2    Hixson, L.J.3    Ahnen, D.J.4    Gerner, E.W.5
  • 32
    • 0032949657 scopus 로고    scopus 로고
    • Carcinogen and dietary lipid regulate ras expression and localization in rat colon without affecting farnesylation kinetics
    • Davidson LA, Lupton JR, Jiang YH, Chapkin RS. Carcinogen and dietary lipid regulate ras expression and localization in rat colon without affecting farnesylation kinetics. Carcinogenesis 1999;20:785-91.
    • (1999) Carcinogenesis , vol.20 , pp. 785-791
    • Davidson, L.A.1    Lupton, J.R.2    Jiang, Y.H.3    Chapkin, R.S.4
  • 35
    • 23944488225 scopus 로고    scopus 로고
    • The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma
    • Conlin A, Smith G, Carey FA, Wolf CR, Steele RJ. The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma. Gut 2005;54:1283-6.
    • (2005) Gut , vol.54 , pp. 1283-1286
    • Conlin, A.1    Smith, G.2    Carey, F.A.3    Wolf, C.R.4    Steele, R.J.5
  • 39
    • 34047261442 scopus 로고    scopus 로고
    • Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: A sequential analysis
    • Zoghbi S, Drouin E, Claustre J, Bara J, Scoazec JY, Plaisancie P. Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis. Int J Oncol 2007;30:489-97.
    • (2007) Int J Oncol , vol.30 , pp. 489-497
    • Zoghbi, S.1    Drouin, E.2    Claustre, J.3    Bara, J.4    Scoazec, J.Y.5    Plaisancie, P.6
  • 40
    • 33845708773 scopus 로고    scopus 로고
    • Progression of tumors arising from large ACF is associated with the MUC5AC expression during rat colon MNNG carcinogenis
    • Maurin N, Forgue-Lafitte ME, Levy P, Zimber A, Bara J. Progression of tumors arising from large ACF is associated with the MUC5AC expression during rat colon MNNG carcinogenis. Int J Cancer 2007;120:477-83.
    • (2007) Int J Cancer , vol.120 , pp. 477-483
    • Maurin, N.1    Forgue-Lafitte, M.E.2    Levy, P.3    Zimber, A.4    Bara, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.