Monitoring of caspase-8/FLICE processing and activation upon Fas stimulation with novel antibodies directed against a cleavage site for caspase-8 and its substrate, FLICE-like inhibitory protein (FLIP)

Journal of Biochemistry

Volumn 132, Issue 1, 2002, Pages 53-62

  Niikura, Yuichi ^a   Nonaka, Takashi ^a   Imajoh Ohmi, Shinobu ^a  

^a THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

Caspase 8; Cleavage site directed antibody; Differentiation; Fas; FLIP

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 8; FAS ANTIBODY; FLICE INHIBITORY PROTEIN; RECOMBINANT GAMMA INTERFERON; SYNTHETIC PEPTIDE; CARRIER PROTEIN; CASPASE; CFLAR PROTEIN, HUMAN; FAS ANTIGEN; GAMMA INTERFERON; HYDROXYCOLECALCIFEROL; MONOCLONAL ANTIBODY; RETINOIC ACID; SIGNAL PEPTIDE;

AMINO TERMINAL SEQUENCE; ANTIBODY SPECIFICITY; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR RECOGNITION; AMINO ACID SEQUENCE; CELL FRACTIONATION; CELL STRAIN U937; CONFOCAL MICROSCOPY; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ORYCTOLAGUS CUNICULUS;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; APOPTOSIS; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASES; CELL DIFFERENTIATION; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMANS; HYDROXYCHOLECALCIFEROLS; INTERFERON TYPE II; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SUBCELLULAR FRACTIONS; SUBSTRATE SPECIFICITY; TRETINOIN; U937 CELLS;

EID: 0036324869     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a003198     Document Type: Article

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