Synthetic oligoribonucleotides-containing secondary structures act as agonists of Toll-like receptors 7 and 8

Biochemical and Biophysical Research Communications

Volumn 386, Issue 3, 2009, Pages 443-448

  Lan, Tao ^a   Putta, Mallikarjuna Reddy ^a   Wang, Daqing ^a   Dai, Meiru ^a   Yu, Dong ^a   Kandimalla, Ekambar R ^a   Agrawal, Sudhir ^a  

^a HYBRIDON INC   (United States)

Author keywords

Immune stimulation; Innate immune responses; Oligoribonucleotides; Secondary structures; Th1 type cytokines; Toll like receptor 7; Toll like receptor 8

Indexed keywords

CHEMOKINE; CYTOKINE; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; OLIGORIBONUCLEOTIDE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VIVO STUDY; MONONUCLEAR CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ANALYSIS; THERMOSTABILITY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BASE SEQUENCE; CELL LINE; CHEMOKINES; CYTOKINES; HUMANS; LIGANDS; MICE; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES; RIBONUCLEASES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

MUS;

EID: 67650066318     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.036     Document Type: Article

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