Synthetic oligoribonucleotides containing arabinonucleotides act as agonists of TLR7 and 8

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 7, 2009, Pages 2044-2047

  Lan, Tao ^a   Bhagat, Lakshmi ^a   Wang, Daqing ^a   Dai, Meiru ^a   Kandimalla, Ekambar R ^a   Agrawal, Sudhir ^a  

^a HYBRIDON INC   (United States)

Author keywords

Agonist; Arabinonucleotides; Immune stimulation; Oligoribonucleotides; Toll like receptor 7; Toll like receptor 8

Indexed keywords

ARABINONUCLEOTIDE; CYTARABINE; GUANINE ARABINOSIDE; OLIGORIBONUCLEOTIDE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR AGONIST; URACIL ARABINOSIDE;

ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN;

ANIMALS; ARABINONUCLEOTIDES; BASE SEQUENCE; CYTOKINES; HUMANS; MICE; MICE, INBRED C57BL; OLIGORIBONUCLEOTIDES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

ARA; MUS;

EID: 61849136281     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.021     Document Type: Article

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