Melatonin inhibits human fibroblast-like synoviocyte proliferation via extracellular signal-regulated protein kinase/P21CIP1/P27 KIP1 pathways

Journal of Pineal Research

Volumn 47, Issue 1, 2009, Pages 70-74

  Nah, Seong Su ^b   Won, Hye Jin ^a,c   Park, Hae Jeong ^a   Ha, Eunyoung ^a   Chung, Joo Ho ^a   Cho, Hong Yon ^c   Baik, Hyung Hwan ^a  

^a Kyung Hee University Hospital   (South Korea)

^b Soonchunhyang University   (South Korea)

^c Korea University   (South Korea)

Author keywords

Extracellular signal regulated protein kinase; Fibroblast like synoviocytes; Melatonin; P21CIP1; P27KIP1; Rheumatoid arthritis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ANTAGONISM; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; WESTERN BLOTTING;

AGED; ARTHRITIS, RHEUMATOID; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; FLAVONOIDS; HUMANS; MELATONIN; MIDDLE AGED; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE;

EID: 67649939037     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2009.00689.x     Document Type: Article

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