Luteolin prevents PDGF-BB-induced proliferation of vascular smooth muscle cells by inhibition of PDGF β-receptor phosphorylation

Biochemical Pharmacology

Volumn 69, Issue 12, 2005, Pages 1715-1721

  Kim, Jin Ho ^a   Jin, Yong Ri ^a   Park, Beoung Soo ^b   Kim, Tack Joong ^c   Kim, Soo Yeon ^a   Lim, Yong ^a   Hong, Jin Tae ^a   Yoo, Hwan Soo ^a   Yun, Yeo Pyo ^a  

^a Chungbuk National University   (South Korea)

^b Seoul National University   (South Korea)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Cell cycle; Luteolin; PDGF R ; Proliferation; Vascular smooth muscle cell

Indexed keywords

LUTEOLIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C GAMMA; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B;

ANIMAL CELL; AORTA MEDIA; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GROWTH INHIBITORS; LUTEOLIN; MUSCLE, SMOOTH, VASCULAR; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA;

EID: 20344396584     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.04.002     Document Type: Article

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