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Volumn 42, Issue 2, 2007, Pages 191-202

Signaling mechanisms of melatonin in antiproliferation of hormone-refractory 22Rv1 human prostate cancer cells: Implications for prostate cancer chemoprevention

Author keywords

Androgen; Chemoprevention; Melatonin; p27Kip1; Prostate specific antigen; Protein kinase A; Protein kinase C

Indexed keywords

2 IODOMELATONIN; 4 PHENYL 2 PROPIONAMIDOTETRALINE; ANDROGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; G PROTEIN COUPLED RECEPTOR; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; LUZINDOLE; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; PROTEIN KINASE C; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

EID: 33846932844     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2006.00406.x     Document Type: Article
Times cited : (66)

References (47)
  • 1
    • 0036157392 scopus 로고    scopus 로고
    • JEMAL A, THOMAS A, MURRAY T et al. Cancer statistics, 2002. CA Cancer J Clin 2002; 52:23-47 (Errata, CA Cancer J Clin 2002;52:119, 181-182).
    • JEMAL A, THOMAS A, MURRAY T et al. Cancer statistics, 2002. CA Cancer J Clin 2002; 52:23-47 (Errata, CA Cancer J Clin 2002;52:119, 181-182).
  • 2
    • 9644279380 scopus 로고    scopus 로고
    • Androgen deprivation therapy for prostate cancer: Current status and future prospects
    • MIYAMOTO H, MESSING EM, CHANG C. Androgen deprivation therapy for prostate cancer: current status and future prospects. Prostate 2004; 61:332-353.
    • (2004) Prostate , vol.61 , pp. 332-353
    • MIYAMOTO, H.1    MESSING, E.M.2    CHANG, C.3
  • 3
    • 0027210003 scopus 로고
    • The melatonin rhythm: Both a clock and a calendar
    • REITER RJ. The melatonin rhythm: both a clock and a calendar. Experientia 1993; 49:654-664.
    • (1993) Experientia , vol.49 , pp. 654-664
    • REITER, R.J.1
  • 4
    • 4644328022 scopus 로고    scopus 로고
    • Mechanisms of cancer inhibition by melatonin
    • REITER RJ. Mechanisms of cancer inhibition by melatonin. J Pineal Res 2004; 37:213-214.
    • (2004) J Pineal Res , vol.37 , pp. 213-214
    • REITER, R.J.1
  • 5
    • 33645455870 scopus 로고    scopus 로고
    • Light pollution, melatonin suppression and cancer growth
    • REITER RJ, GULTEKIN F, MANCHESTER LC et al. Light pollution, melatonin suppression and cancer growth. J Pineal Res 2006; 40:357-358.
    • (2006) J Pineal Res , vol.40 , pp. 357-358
    • REITER, R.J.1    GULTEKIN, F.2    MANCHESTER, L.C.3
  • 6
    • 0029838824 scopus 로고    scopus 로고
    • Cancer of the male genital tract in circumpolar Inuit
    • PRENER A, STORM HH, NIELSEN NH. Cancer of the male genital tract in circumpolar Inuit. Acta Oncol 1996; 35:589-593.
    • (1996) Acta Oncol , vol.35 , pp. 589-593
    • PRENER, A.1    STORM, H.H.2    NIELSEN, N.H.3
  • 9
    • 33645499471 scopus 로고    scopus 로고
    • Does incidence of breast cancer and prostate cancer decrease with increasing degree of visual impairment
    • PUKKALA E, OJAMO M, RUDANKO SL et al. Does incidence of breast cancer and prostate cancer decrease with increasing degree of visual impairment. Cancer Causes Control 2006; 17:573-576.
    • (2006) Cancer Causes Control , vol.17 , pp. 573-576
    • PUKKALA, E.1    OJAMO, M.2    RUDANKO, S.L.3
  • 10
    • 0020436536 scopus 로고
    • Age-dependent reduction in serum melatonin concentrations in healthy human subjects
    • IGUCHI H, KATO KI, IBAYASHI H. Age-dependent reduction in serum melatonin concentrations in healthy human subjects. J Clin Endocrinol Metab 1982; 55:27-29.
    • (1982) J Clin Endocrinol Metab , vol.55 , pp. 27-29
    • IGUCHI, H.1    KATO, K.I.2    IBAYASHI, H.3
  • 11
    • 0022973346 scopus 로고
    • Human melatonin production decreases with age
    • SACK RL, LEWY AJ, ERB DL et al. Human melatonin production decreases with age. J Pineal Res 1986; 3:379-388.
    • (1986) J Pineal Res , vol.3 , pp. 379-388
    • SACK, R.L.1    LEWY, A.J.2    ERB, D.L.3
  • 12
    • 0023863323 scopus 로고
    • Alterations in nocturnal serum melatonin levels in humans with growth and aging
    • WALDHAUSER F, WEISZENBACHER G, TATZER E et al. Alterations in nocturnal serum melatonin levels in humans with growth and aging. J Clin Endocrinol Metab 1988; 66:648-652.
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 648-652
    • WALDHAUSER, F.1    WEISZENBACHER, G.2    TATZER, E.3
  • 13
    • 0036913853 scopus 로고    scopus 로고
    • Aging and the circadian rhythm of melatonin; a cross-sectional study of Chinese subjects 30-110 yr of age
    • ZHAO ZY, XIE Y, FU YR et al. Aging and the circadian rhythm of melatonin; a cross-sectional study of Chinese subjects 30-110 yr of age. Chronobiol Int 2002; 19:1171-1182.
    • (2002) Chronobiol Int , vol.19 , pp. 1171-1182
    • ZHAO, Z.Y.1    XIE, Y.2    FU, Y.R.3
  • 14
    • 0026713113 scopus 로고
    • Melatonin and 6-sulfatoxymelatonin circadian rhythms in serum and urine of primary prostate cancer patients; evidence for reduced pineal activity and relevance of urinary determinations
    • BARTSCH C, BARTSCH H, SCHMIDT A et al. Melatonin and 6-sulfatoxymelatonin circadian rhythms in serum and urine of primary prostate cancer patients; evidence for reduced pineal activity and relevance of urinary determinations. Clin Chim Acta 1992; 209:153-167.
    • (1992) Clin Chim Acta , vol.209 , pp. 153-167
    • BARTSCH, C.1    BARTSCH, H.2    SCHMIDT, A.3
  • 15
    • 0033626587 scopus 로고    scopus 로고
    • 1 receptor and attenuated sex-steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells
    • 1 receptor and attenuated sex-steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells. J Pineal Res 2000; 29:172-183.
    • (2000) J Pineal Res , vol.29 , pp. 172-183
    • XI, S.C.1    TAM, P.C.2    BROWN, G.M.3
  • 17
    • 0036603478 scopus 로고    scopus 로고
    • SIU SWF, LAU KW, TAM PC et al. Melatonin and prostate cancer cell proliferation: interplay with castration, epidermal growth factor, and androgen sensitivity. Prostate 2002; 52:106-122 (Erratum, Prostate 2002;52:252).
    • SIU SWF, LAU KW, TAM PC et al. Melatonin and prostate cancer cell proliferation: interplay with castration, epidermal growth factor, and androgen sensitivity. Prostate 2002; 52:106-122 (Erratum, Prostate 2002;52:252).
  • 18
    • 0033062020 scopus 로고    scopus 로고
    • Hormonal interactions in human prostate tumor LNCaP cells
    • LUPOWITZ Z, ZISAPEL N. Hormonal interactions in human prostate tumor LNCaP cells. J Steroid Biochem Mol Biol 1999; 68:83-88.
    • (1999) J Steroid Biochem Mol Biol , vol.68 , pp. 83-88
    • LUPOWITZ, Z.1    ZISAPEL, N.2
  • 19
    • 0034145408 scopus 로고    scopus 로고
    • Antiproliferative action of melatonin on human prostate cancer LNCaP cells
    • MORETTI RM, MARELLI MM, MAGGI R et al. Antiproliferative action of melatonin on human prostate cancer LNCaP cells. Oncol Rep 2000; 7:347-351.
    • (2000) Oncol Rep , vol.7 , pp. 347-351
    • MORETTI, R.M.1    MARELLI, M.M.2    MAGGI, R.3
  • 20
    • 0033768153 scopus 로고    scopus 로고
    • Growth-inhibitory activity of melatonin on human androgen-independent DU145 prostate cancer cells
    • MARELLI MM, LIMONTA P, MAGGI R et al. Growth-inhibitory activity of melatonin on human androgen-independent DU145 prostate cancer cells. Prostate 2000; 45:238-244.
    • (2000) Prostate , vol.45 , pp. 238-244
    • MARELLI, M.M.1    LIMONTA, P.2    MAGGI, R.3
  • 21
    • 14944362307 scopus 로고    scopus 로고
    • Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism
    • SAINZ RM, MAYO JC, TAN DX et al. Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism. Prostate 2005; 63:29-43.
    • (2005) Prostate , vol.63 , pp. 29-43
    • SAINZ, R.M.1    MAYO, J.C.2    TAN, D.X.3
  • 24
    • 0029972613 scopus 로고    scopus 로고
    • Melatonin receptors step into the light; cloning and classification of subtypes
    • REPPERT SM, WEAVER DR, GODSON C. Melatonin receptors step into the light; cloning and classification of subtypes. Trends Pharmacol Sci 1996; 17:100-102.
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 100-102
    • REPPERT, S.M.1    WEAVER, D.R.2    GODSON, C.3
  • 25
    • 0343714601 scopus 로고    scopus 로고
    • PEREZ-STABLE CM, POZAS A, ROOS BA. A role for GATA transcription factors in the androgen regulation of the prostate-specific antigen gene enhancer. Mol Cell Endocrinol 2000; 167:43-53.
    • PEREZ-STABLE CM, POZAS A, ROOS BA. A role for GATA transcription factors in the androgen regulation of the prostate-specific antigen gene enhancer. Mol Cell Endocrinol 2000; 167:43-53.
  • 27
    • 0042532260 scopus 로고    scopus 로고
    • kip1 deregulation in cancer: Down regulation or mislocalization
    • kip1 deregulation in cancer: down regulation or mislocalization. Cell Cycle 2002; 1:394-400.
    • (2002) Cell Cycle , vol.1 , pp. 394-400
    • VIGLIETTO, G.1    MOTTI, M.L.2    FUSCO, A.3
  • 29
    • 0030951234 scopus 로고    scopus 로고
    • Physiological melatonin inhibition of human breast cancer cell growth in vitro: Evidence for a glutathione-mediated pathway
    • BLASK DE, WILSON ST, ZALATAN F. Physiological melatonin inhibition of human breast cancer cell growth in vitro: evidence for a glutathione-mediated pathway. Cancer Res 1997; 57:1909-1914.
    • (1997) Cancer Res , vol.57 , pp. 1909-1914
    • BLASK, D.E.1    WILSON, S.T.2    ZALATAN, F.3
  • 31
    • 0034786610 scopus 로고    scopus 로고
    • Melatonin elicits nuclear exclusion of the human androgen receptor and attenuates its activity
    • RIMLER A, CULIG Z, LEVY RIMLER G et al. Melatonin elicits nuclear exclusion of the human androgen receptor and attenuates its activity. Prostate 2001; 49:145-154.
    • (2001) Prostate , vol.49 , pp. 145-154
    • RIMLER, A.1    CULIG, Z.2    LEVY RIMLER, G.3
  • 32
    • 0033567891 scopus 로고    scopus 로고
    • Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events
    • BLASK DE, SAUER LA, DAUCHY RT et al. Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. Cancer Res 1999; 59:4693-4701.
    • (1999) Cancer Res , vol.59 , pp. 4693-4701
    • BLASK, D.E.1    SAUER, L.A.2    DAUCHY, R.T.3
  • 33
    • 31544465214 scopus 로고    scopus 로고
    • Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin
    • MARTÍN V, HERRERA F, CARRERA- GONZALEZ P et al. Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin. Cancer Res 2006; 66:1081-1088.
    • (2006) Cancer Res , vol.66 , pp. 1081-1088
    • MARTÍN, V.1    HERRERA, F.2    CARRERA- GONZALEZ, P.3
  • 35
    • 0032587495 scopus 로고    scopus 로고
    • kip1: A multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers
    • kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am J Pathol 1999; 154:313-323.
    • (1999) Am J Pathol , vol.154 , pp. 313-323
    • LLOYD, R.V.1    ERICKSON, L.A.2    JIN, L.3
  • 36
    • 0345561574 scopus 로고    scopus 로고
    • Expression of p27/kip1 is down-regulated in human prostate carcinoma progression
    • FERNÁNDEZ PL, ARCE Y, FARRÉ X et al. Expression of p27/kip1 is down-regulated in human prostate carcinoma progression. J Pathol 1999; 187:563-566.
    • (1999) J Pathol , vol.187 , pp. 563-566
    • FERNÁNDEZ, P.L.1    ARCE, Y.2    FARRÉ, X.3
  • 37
    • 13044305289 scopus 로고    scopus 로고
    • SUN H, LESCHE R, LI DM et al. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-triphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci U S A 1999; 96:6199-6204.
    • SUN H, LESCHE R, LI DM et al. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-triphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci U S A 1999; 96:6199-6204.
  • 39
    • 0032511848 scopus 로고    scopus 로고
    • Kip1 is haplo-insufficient for tumor suppression
    • Kip1 is haplo-insufficient for tumor suppression. Nature 1998; 396:177-180.
    • (1998) Nature , vol.396 , pp. 177-180
    • FERO, M.L.1    RANDEL, E.2    GURLEY, K.E.3
  • 40
    • 0028986932 scopus 로고
    • Kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
    • Kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res 1995; 55:1211-1214.
    • (1995) Cancer Res , vol.55 , pp. 1211-1214
    • PONCE-CASTANEDA, M.V.1    LEE, M.H.2    LATRES, E.3
  • 42
    • 2942597644 scopus 로고    scopus 로고
    • VIJAYALAXMI, REITER RJ, TAN DX et al. Melatonin as a radioprotective agent: a review. Int J Radiat Oncol Biol Phys 2004; 59:639-653.
    • VIJAYALAXMI, REITER RJ, TAN DX et al. Melatonin as a radioprotective agent: a review. Int J Radiat Oncol Biol Phys 2004; 59:639-653.
  • 43
    • 0034749615 scopus 로고    scopus 로고
    • Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state
    • MURILLO H, HUANG H, SCHMIDT LJ et al. Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology 2001; 142:4795-4805.
    • (2001) Endocrinology , vol.142 , pp. 4795-4805
    • MURILLO, H.1    HUANG, H.2    SCHMIDT, L.J.3
  • 45
    • 0026517072 scopus 로고
    • Tumor-promoting phorbol ester down-regulates the androgen induction of prostate-specific antigen in a human prostatic cell line
    • ANDREWS PE, YOUNG CYF, MONTGOMERY BT et al. Tumor-promoting phorbol ester down-regulates the androgen induction of prostate-specific antigen in a human prostatic cell line. Cancer Res 1992; 52:1525-1529.
    • (1992) Cancer Res , vol.52 , pp. 1525-1529
    • ANDREWS, P.E.1    YOUNG, C.Y.F.2    MONTGOMERY, B.T.3
  • 46
    • 0035660603 scopus 로고    scopus 로고
    • Evaluation of signal transduction pathways mediating the nuclear exclusion of the androgen receptor by melatonin
    • LUPOWITZ Z, RIMLER A, ZISAPEL N. Evaluation of signal transduction pathways mediating the nuclear exclusion of the androgen receptor by melatonin. Cell Mol Life Sci 2001; 58:2129-2135.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 2129-2135
    • LUPOWITZ, Z.1    RIMLER, A.2    ZISAPEL, N.3
  • 47
    • 0029617713 scopus 로고
    • Melatonin madness
    • REPPERT SM, WEAVER DR. Melatonin madness. Cell 1995; 83:1059-1062.
    • (1995) Cell , vol.83 , pp. 1059-1062
    • REPPERT, S.M.1    WEAVER, D.R.2


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