Melatonin in rheumatoid arthritis: A disease-promoting and modulating hormone? [3]

Clinical and Experimental Rheumatology

Volumn 20, Issue 6, 2002, Pages 872-873

  Maestroni, George J M ^a   Sulli, A ^b   Pizzorni, C ^b   Villaggio, B ^b   Cutolo, M ^b  

^a INSTITUTE OF PATHOLOGY   (Switzerland)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HYDROCORTISONE; MELATONIN;

ADULT; AGED; BINDING SITE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HORMONE BLOOD LEVEL; HORMONE RELEASE; HORMONE SYNTHESIS; HUMAN; HYDROCORTISONE BLOOD LEVEL; IMMUNITY; IMMUNOCOMPETENT CELL; LETTER; MACROPHAGE ACTIVATION; MALE; METABOLISM; MODULATION; PATHOGENESIS; PRIORITY JOURNAL; REPRODUCTION; RHEUMATOID ARTHRITIS; SYMPTOMATOLOGY; SYNOVIAL FLUID LEVEL; THERMOREGULATION; BLOOD; CYTOLOGY; MACROPHAGE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNOVIAL FLUID;

ARTHRITIS, RHEUMATOID; BINDING SITES; CIRCADIAN RHYTHM; FEMALE; HUMANS; MACROPHAGES; MALE; MELATONIN; MIDDLE AGED; SYNOVIAL FLUID;

EID: 0036899738     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (10)

1. STRAUB RH, CUTOLO M: Involvement of the hypothalamic-pituitary-adrenal/gonadal axis and the peripheral nervous system in rheumatoid arthritis: Viewpoint based on a systemic pathogenetic role. Arthritis Rheum 2001; 44: 493-507.
2. PETROVSKY N, HARRISON L: The chronobiology of human cytokine production. Int Rev Immunol 1998; 16: 635-49.
3. YU H-S and REITER RJ (Eds.): Melatonin. Biosynthesis, Physiological Effects and Clinical Applications. Boca Raton, CRC Press, 1993.
4. MAESTRONI GJM: The immunotherapeutic potential of melatonin. Exp Opin Invet Drugs 2001; 10: 467-76.
5. GARCIA-MAURIÑO S, GONZALES-HABA MG, CALVO JR, et al.: Melatonin enhances IL-2, II-6, and IFN-g production by human circulating CD4+ cells. J Imnumol 1997; 159: 574-81.
6. PETROVSKY N, HARRISON L: Diurnal rhythmicity of human cytokine production: A dynamic disequilibrium in T helper cell type 1/T helper cell type 2 balance. J Immunol 1996; 158: 5163-8.
7. FIORINA P, LATTUADA G, SILVESTRINI C, PONARI O, DALL'AGLIO P: Disruption of nocturnal melatonin rhythm and immunological involvement in ischaemic stroke patients. Scand J Immunol 1999; 50: 228-31.
8. HANSSON I, HOLMDAHL R, MATTSSON R: The pineal hormone melatonin exaggerates development of collagen-induced arthritis in mice. J Neuroimmunol 1992; 39: 23-31.
9. CUTOLO M, VILLAGGIO B, CANDIDO F et al.: Melatonin influences interleukin-12 and nitric oxide production by primary cultures of rheumatoid synovial macrophages and THP-1 cells. Ann NY Acad Sci 1999; 876: 246-54.
10. CONTI A, CONCONI S, HERTENS E, SKWARLO-SONTA K, MARKOWSKA M, MAESTRONI G: Evidence for melatonin synthesis in mouse and human bone marrow cells. J Pineal Res 2000; 28: 193-202.