-
2
-
-
0030658039
-
Oncogenic transcription factors in the human acute leukemias
-
(1997)
Science
, vol.278
, pp. 1059-1064
-
-
Look, A.T.1
-
3
-
-
0032878921
-
The fusion gene Cbfb-MYHII blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukemia
-
(1999)
Nat. Genet.
, vol.23
, pp. 144-146
-
-
Castilla, L.H.1
-
4
-
-
0034665765
-
Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model
-
(2000)
Blood
, vol.96
, pp. 2108-2115
-
-
Rhoades, K.L.1
-
7
-
-
0030933277
-
Oncoprotein networks
-
(1997)
Cell
, vol.88
, pp. 333-346
-
-
Hunter, T.1
-
8
-
-
0033151533
-
Constitutive activation of extracellular signal-regulated kinase in human acute leukemias: Combined role of activation of MEK, hyperexptession of extracellular signal-regulated kinase, and downregulation of a phosphatase, PACI
-
(1999)
Blood
, vol.93
, pp. 3893-3899
-
-
Kim, S.C.1
-
9
-
-
0030972025
-
Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells
-
(1997)
Leukemia
, vol.11
, pp. 479-484
-
-
Towatari, M.1
-
10
-
-
0034598830
-
Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
-
(2000)
Oncogene
, vol.19
, pp. 624-631
-
-
Hayakawa, F.1
-
11
-
-
0034719381
-
A conditionally-active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells
-
(2000)
Oncogene
, vol.19
, pp. 526-536
-
-
Blalock, W.L.1
-
12
-
-
0034123442
-
Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells
-
(2000)
Leukemia
, vol.14
, pp. 1080-1096
-
-
Blalock, W.L.1
-
13
-
-
0034678609
-
Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia
-
(2000)
EMBO J.
, vol.19
, pp. 1827-1838
-
-
Liu, Q.1
-
17
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
(1999)
Nat. Med.
, vol.5
, pp. 810-816
-
-
Sebolr-Leopold1
-
18
-
-
0028793210
-
Effect of interleukin-1 beta converting enzyme inhibitor on acute myelogenous leukemia progenitor proliferation
-
(1995)
Blood
, vol.86
, pp. 4594-4602
-
-
Estrov, Z.1
-
22
-
-
0032541633
-
Anti-apoptotic versus pro-apoptotic signal transduction: Checkpoints and stop signs along the road to death
-
(1998)
Oncogene
, vol.17
-
-
Jarpe, M.B.1
-
23
-
-
0032528172
-
Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest
-
(1998)
Cancer Res.
, vol.58
, pp. 3163-3172
-
-
Yen, A.1
Roberson, M.S.2
Varvayanis, S.3
Lee, A.T.4
-
26
-
-
0034662968
-
Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9609-9614
-
-
Lenferink, A.E.1
-
28
-
-
0033559597
-
Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis
-
(1999)
Cancer Res.
, vol.59
, pp. 1259-1267
-
-
Wang, Z.1
-
30
-
-
0033971171
-
Prognostic significance of the cell cycle inhibitor p27Kip1 in acute myeloid leukemia
-
(2000)
Leukemia
, vol.14
, pp. 28-33
-
-
Yokozawa, T.1
-
31
-
-
0029102010
-
High levels of constitutive WAF1/Cip1 protein are associated with chemoresistance in acute myelogenous leukemia
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1051-1057
-
-
Zhang, W.1
-
34
-
-
0032721858
-
Expression of bcl-2-related genes in normal and AML progenitors: Changes induced by chemotherapy and retinoic acid
-
(1999)
Leukemia
, vol.13
, pp. 1881-1892
-
-
Andreeff, M.1
-
35
-
-
0030669281
-
Modulation of idarubicin-induced apoptosis in human acute myeloid leukemia blasts by all-trans retinoic acid, 1,25(OH)2 vitamin D3, and granulocytemacrophage colony-stimulating factor
-
(1997)
Blood
, vol.90
, pp. 4578-4587
-
-
Ketley, N.J.1
Allen, P.D.2
Kelsey, S.M.3
Newland, A.C.4
-
36
-
-
0034907636
-
Pharmacologic interruption of the mitogen-activated extracellular-regulated kinase/mitogen-activated protein kinase signal transduction pathway: Potential role in promoting cytotoxic drug action
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 775-783
-
-
Dent, P.1
Grant, S.2
-
37
-
-
0031785213
-
Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 844-856
-
-
Jatvis, W.D.1
-
38
-
-
0034948613
-
Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogenactivated protein kinase pathway
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 143-154
-
-
Yu, C.1
Wang, S.2
Dent, P.3
Grant, S.4
-
40
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
(1996)
Nat. Med.
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
-
43
-
-
0033199619
-
Megakaryocyte growth and development factor-induced proliferation and differentiation are regulated by the mitogen-activated protein kinase pathway in primitive cord blood hematopoietic progenitors
-
(1999)
Blood
, vol.94
, pp. 1601-1613
-
-
Fichelson, S.1
-
44
-
-
0035869396
-
Cell-cycle-dependent activation of mitogen-activated protein kinase kinase (MEK-1/2) in myeloid leukemia cell lines and induction of growth inhibition and apoptosis by inhibitors of RAS signaling
-
(2001)
Blood
, vol.97
, pp. 1823-1834
-
-
Morgan, M.A.1
Dolp, O.2
Reuter, C.W.3
|