Diarylheptanoid hirsutenone prevents tumor necrosis factor-α-stimulated production of inflammatory mediators in human keratinocytes through NF-κB inhibition

International Immunopharmacology

Volumn 9, Issue 9, 2009, Pages 1097-1104

  Lee, Chung Soo ^a   Ko, Hyun Hee ^a   Seo, Seong Jun ^b   Choi, Young Wook ^a   Lee, Min Won ^a   Myung, Soon Chul ^b   Bang, Hyoweon ^a  

^a Chung Ang University   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

Cytokine and chemokine production; Hirsutenone; Inhibitory effect; Keratinocytes; NF B; Tumor necrosis factor

Indexed keywords

3 (4 TERT BUTYLPHENYLSULFONYL) 2 PROPENENITRILE; ACETYLCYSTEINE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CUTANEOUS T CELL ATTRACTING CHEMOKINE; CYCLOSPORIN A; DEXAMETHASONE; HIRSUTENONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG INHIBITION; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ALNUS; CATECHOLS; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINE CCL27; DERMATITIS, ATOPIC; DIARYLHEPTANOIDS; DINOPROSTONE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; KERATINOCYTES; NF-KAPPA B; PHYTOTHERAPY; PLANT EXTRACTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649400315     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.05.006     Document Type: Article

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