PCB126 enhanced the genotoxicity of BaP in HepG2 cells by modulating metabolic enzyme and DNA repair activities

Toxicology Letters

Volumn 189, Issue 2, 2009, Pages 91-95

  Wei, Wei ^a   Zhang, Chi ^a   Liu, Ai Lin ^a   Xie, Shao Hua ^a   Chen, Xue Min ^a   Lu, Wen Qing ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Benzo(a)pyrene; CYP1A1; DNA damage repair; MN; NER; PCB126

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; ALPHA NAPHTHOFLAVONE; BENZO[A]PYRENE; CYTOCHROME P450 1A1; DIMETHYL SULFOXIDE; GUANINE NUCLEOTIDE EXCHANGE FACTOR;

ARTICLE; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ENZYME METABOLISM; GENOTOXICITY; HUMAN; HUMAN CELL; MICRONUCLEUS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BENZO(A)PYRENE; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; DNA REPAIR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION REGULATION; HUMANS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; POLYCHLORINATED BIPHENYLS; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

EID: 67649390732     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.03.009     Document Type: Article

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