Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: Involvement of two excision repair mechanisms in vitro

Carcinogenesis

Volumn 19, Issue 7, 1998, Pages 1239-1246

  Braithwaite, Elena ^a   Wu, Xiaohua ^a   Wang, Zhigang ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; BENZ[A]ANTHRACENE DERIVATIVE; DNA; POLYCYCLIC AROMATIC HYDROCARBON;

ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; EXCISION REPAIR; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; CARCINOGENS; CELL-FREE SYSTEM; DNA; DNA DAMAGE; DNA REPAIR; HELA CELLS; HUMANS; POLYCYCLIC HYDROCARBONS, AROMATIC;

EID: 0031903666     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.7.1239     Document Type: Article

References (36)

1. Phillips, D.H. and Grover, P.L. (1994) Polycyclic hydrocarbon activation: bay regions and beyond. Drug Metab. Rev., 26, 443-467.
2. Peltonen, K. and Dipple, A. (1995) Polycyclic aromatic hydrocarbons: chemistry of DNA adduct formation. J. Occup. Environ. Med., 37, 52-58.
3. Friedberg, E.C., Walker, G.C. and Siede, W. (1995) DNA Repair and Mutagenesis. American Society for Microbiology Press, Washington, DC.
4. Glatt, H., Harvey, R.G., Phillips, D.H., Hewer, A. and Grover, P.L. (1989) Influence of the alkyl substituent on mutagenicity and covalent DNA binding of bay region diolepoxides of 7-methyl-and 7-ethylbenz[a]-anthracene in Salmonella and V79 Chinese hamster cells. Cancer Res., 49, 1778-1782.
5. Bigger, C.A.H., Flickinger, D.J., Strandberg, J., Pataki, J., Harvey, R.G. and Dipple, A. (1990) Mutational specificity of the anti-1,2-dihydrodiol 3,4-epoxide of 5-methylchrysene. Carcinogenesis, 11, 2263-2265.
6. Bigger, C.A.H., Flickinger, D.J., St John, J., Harvey, R.G. and Dipple, A. (1991) Preferential mutagenesis at GGC base pairs by the anti-3,4-dihydrodiol 1,2-epoxide of 7-methylbenz[a]anthracene. Mol. Carcinogen., 4, 176-179.
7. Yang, J.-L., Maher, V.M. and McCormick, J.J. (1987) Kinds of mutation formed when a shuttle vector containing adducts of (±)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene replicates in human cells. Proc. Natl Acad. Sci. USA, 84, 3787-3791.
8. Wood, R.D. (1997) Nucleotide excision repair in mammalian cells. J. Biol. Chem., 272, 23465-23468.
9. Kubota, Y., Nash, R.A., Klungland, A., Schar, P., Barnes, D.E. and Lindahl, T. (1996) Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase β and the XRCC1 protein. EMBO J., 15, 6662-6670.
10. Nicholl, I.D., Nealon, K. and Kenny, M.K. (1997) Reconstitution of human base excision repair with purified proteins. Biochemistry, 36, 7557-7566.
11. van Houten, B. (1990) Nucleotide excision repair in Escherichia coli. Microbiol. Rev., 54, 18-51.
12. Gunz, D., Hess, M.T. and Naegeli, H. (1996) Recognition of DNA adducts by human nucleotide excision repair: evidence for a thermodynamic probing mechanism. J. Biol. Chem., 271, 25089-25098.
13. Koostra, A. (1982) Formation and removal of B[a]P diol epoxide-DNA adducts in human fibroblasts. Carcinogenesis, 3, 953-955.
14. McLeod, M.C., Daylong, A., Adair, G. and Humphrey, R.M. (1991) Differences in the rate of DNA adduct removal and the efficiency of mutagenesis for two benzo[a]pyrene diol epoxides in CHO cells. Mutat. Res., 261, 267-279.
15. Venkatachalam, S., Denissenko, M. and Wani, A.A. (1995) DNA repair in human cells: quantitative assessment of bulky anti-BPDE-DNA adducts by non-competitive immunoassays. Carcinogenesis, 16, 2029-2036.
16. Blakey, D.H. and Douglas, G.R. (1990) The role of excision repair in the removal of transient benzo[a]pyrene-induced DNA lesions in Chinese hamster ovary cells. Mutat. Res., 236, 35-41.
17. Hoffmann, D. and Hecht, S.S. (1990) Advances in tobacco carcinogenesis. In Cooper, C.S. and Grover, P.L. (eds) Handbook of Experimental Pharmacology - Chemical Carcinogenesis and Mutagenesis. Springer-Verlag, Berlin, Vol. 94, pp. 63-102.
18. Wang, Z., Wu, X. and Friedberg, E.C. (1995) The detection and measurement of base and nucleotide excision repair in cell-free extracts of the yeast Saccharomyces cerevisiae. Methods: A Companion to Methods in Enzymol., 7, 177-186.
19. McCarthy, M.J., Rosenblatt, J.I. and Lloyd, R.S. (1996) A modified quantitative polymerase chain reaction assay for measuring gene-specific repair of UV photoproducts in human cells. Mutat. Res., 363, 57-66.
20. Yakes, F.M. and Van Houten, B. (1997) Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl Acad. Sci. USA, 94, 514-519.
21. Wood, R.D., Robins, P. and Lindahl, T. (1988) Complementation of the Xeroderma pigmentosum DNA repair defect in cell-free extracts. Cell, 53, 97-106.
22. Wang, Z., Wu, X. and Friedberg, E.C. (1991) Nucleotide excision repair of DNA by human cell extracts is suppressed in reconstituted nucleosomes. J. Biol. Chem., 266, 22472-22478.
23. Cheng, S.C., Hilton, B.D., Roman, J.M. and Dipple, A. (1989) DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo[a]pyrene dihydrodiol epoxide. Chem. Res. Toxicol., 2, 334-340.
24. Osborne, M.R., Jacobs, S., Harvey, R.G. and Brookes, P. (1981) Minor products from the reaction of (+) and (-) benzo[a]pyrene-anti-diolepoxide with DNA. Carcinogenesis, 12, 553-558.
25. Wood, A.W., Chang, R.L., Levin, W., Lehr, R.E., Schaefer-Ridder, M., Karle, G.M., Jerina, D.M. and Conney, A.H. (1977) Mutagenecity and cytotoxicity of benz[a]anthracene diol epoxides and tetrahydro epoxides: exceptional activity of the bay region 1,2-epoxides. Proc. Natl Acad. Sci. USA, 74, 2746-2750.
26. Wood, A.W., Levin, W., Chang, R.L., Lehr, R.E., Schaefer-Redder, M., Karle, J.M., Jerina, D.M. and Conney, A.H. (1977) Tumorigenicity of five dihydrodiols of benz[a]anthracene on mouse skin: exceptional activity of benz[a]anthracene 3,4-dihydrodiol. Proc. Natl Acad. Sci. USA, 74, 3176-3179.
27. Slaga, T.J., Huberman, E., Selkirk, J.K., Harvey, R.G. and Bracken, W.M. (1978) Carcinogenicity and mutagenicity of benz[a]anthracene diols and diol-epoxides. Cancer Res., 38, 1699-1704.
28. Chang, R.L., Levin, W., Wood, A.W., Yagi, H., Tada, M., Vyas, K.P., Jerina, D.M. and Conney, A.H. (1983) Tumorigenicity of enantiomers of chrysene 1,2-dihydrodiol and of the diastereomeric bay-region chrysene 1,2-diol-3,4-epoxides on mouse skin and in newborn mice. Cancer Res., 43, 192-196.
29. Windsor, S.A., Tinker, M.H., Osborne, M.R. and Seidel, A. (1996) Studies of the binding of diolepoxide metabolites of polycyclic aromatic hydrocarbons to DNA using electrofluorescence polarization spectroscopy. Carcinogenesis, 17, 605-608.
30. Doetsch, P.W. and Cunningham, R.P. (1990) The enzymology of apurinic/ apyrimidinic endonucleases. Mutat. Res., 236, 173-201.
31. Lawley, P.D. and Brookes, P. (1963) Further studies on the alkylation of nucleic acids and their constitutent nucleotides. Biochem. J., 89, 127-138.
32. Drinkwater, N.R., Miller, E.C. and Miller, J.A. (1980) Estimation of apurinic/ apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens. Biochemistry, 19, 5087-5092.
33. Ochi, T., Ishiguro, T. and Ohsawa, M. (1986) Induction of alkaline-labile sites in DNA by benzo[a]pyrene and the repair of those lesions in cultured Chinese hamster cells. Mutat. Res., 165, 31-38.
34. Day, R.S., Scudiero, D. and Dimattina, M. (1978) Excision repair by human fibroblasts of DNA damaged by r-7,t-8-dihyroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene. Mutat. Res., 50, 383-394.
35. van Houten, B., Masker, W.E., Carrier, W.L. and Regan, J.D. (1986) Quantitation of carcinogen-induced DNA damage and repair in human cells with the UVR ABC excision nuclease from E.coli. Carcinogenesis. 7, 83-87.
36. Buening, M.K., Wislocki, P.G., Levin, W., Yagi, H., Thakker, D.R., Akagi, H., Koreeda, M., Jerina, D.M. and Conney, A.H. (1978) Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene. Proc. Natl Acad. Sci. USA, 75, 5358-5361.