Prenatal 3,3′,4,4′,5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1, 1B1, and AhR by 7,12-dimethylbenz[a]anthracene

Toxicology and Applied Pharmacology

Volumn 210, Issue 3, 2006, Pages 200-211

  Wakui, Shin ^a   Yokoo, Kiyofumi ^a   Takahashi, Hiroyuki ^b   Muto, Tomoko ^c   Suzuki, Yoshihiko ^a   Kanai, Yoshikatsu ^c   Hano, Hiroshi ^b   Furusato, Masakuni ^c   Endou, Hitoshi ^c  

^a AZABU UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KYORIN UNIVERSITY   (Japan)

Author keywords

AhR; CYP1; DMBA; Liver; PCB126; Rat

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; 7,12 DIMETHYLBENZ[A]ANTHRACENE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CARCINOMA; CATALYSIS; CONCEPTION; CONTROLLED STUDY; FEMALE; IMMUNOHISTOCHEMISTRY; NONHUMAN; OXIDATION; PRENATAL EXPOSURE; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CARCINOGENS, ENVIRONMENTAL; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENVIRONMENTAL POLLUTANTS; ENZYME INDUCTION; FEMALE; LIVER; MATERNAL EXPOSURE; POLYCHLORINATED BIPHENYLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

ANIMALIA;

EID: 30844440776     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.04.022     Document Type: Article

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