Monocytic differentiation of leukemic HL-60 cells induced by co-treatment with TNF-α and MK886 requires activation of pro-apoptotic machinery

European Journal of Haematology

Volumn 83, Issue 1, 2009, Pages 35-47

  Procházková, Jiřina ^a   Stixová, Lenka ^a,b   Souček, Karel ^a   Hofmanová, Jiřina ^a,b   Kozubík, Alois ^a  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Caspases; MAPK; MK886; NF B; TNF

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; CD11B ANTIGEN; CD14 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CASPASE; CYSTEINE PROTEINASE INHIBITOR; INDOLE DERIVATIVE; LIPOXYGENASE INHIBITOR; PEPTIDE CHLOROMETHYL KETONE;

APOPTOSIS; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL STRAIN HL 60; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; DRUG ANTAGONISM; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROMYELOCYTIC LEUKEMIA; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; CASPASES; CELL DIFFERENTIATION; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; INDOLES; LEUKEMIA, PROMYELOCYTIC, ACUTE; LIPOXYGENASE INHIBITORS; MAP KINASE SIGNALING SYSTEM; MONOCYTES; NF-KAPPA B; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649325460     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2009.01240.x     Document Type: Article

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