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Volumn 24, Issue 36, 2006, Pages 5703-5710

Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European acute promyelocytic leukemia group

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; DAUNORUBICIN; MERCAPTOPURINE; METHOTREXATE; RETINOIC ACID; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE;

EID: 34247369329     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2006.08.1596     Document Type: Article
Times cited : (153)

References (49)
  • 1
    • 0017162163 scopus 로고
    • Proposals for the classification of the acute leukaemias: French-American-British (FAB) co-operative group
    • Bennett JM, Catovsky D, Daniel MT, et al: Proposals for the classification of the acute leukaemias: French-American-British (FAB) co-operative group. Br J Haematol 33:451-458, 1976
    • (1976) Br J Haematol , vol.33 , pp. 451-458
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3
  • 2
    • 0026557073 scopus 로고
    • Reassessing the hemostatic disorder associated with acute promyelocytic leukemia
    • Tallman MS, Kwaan HC: Reassessing the hemostatic disorder associated with acute promyelocytic leukemia. Blood 79:543-553, 1992
    • (1992) Blood , vol.79 , pp. 543-553
    • Tallman, M.S.1    Kwaan, H.C.2
  • 3
    • 0021345113 scopus 로고
    • Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia
    • Larson RA, Kondo K, Vardiman JW, et al: Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia. Am J Med 76: 827-841, 1984
    • (1984) Am J Med , vol.76 , pp. 827-841
    • Larson, R.A.1    Kondo, K.2    Vardiman, J.W.3
  • 4
    • 0025875679 scopus 로고
    • The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
    • de The H, Lavau C, Marchio A, et al: The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR. Cell 66:675-684, 1991
    • (1991) Cell , vol.66 , pp. 675-684
    • de The, H.1    Lavau, C.2    Marchio, A.3
  • 5
    • 0025780876 scopus 로고
    • Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML
    • Kakizuka A, Miller WH Jr, Umesono K, et al: Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 66: 663-674, 1991
    • (1991) Cell , vol.66 , pp. 663-674
    • Kakizuka, A.1    Miller Jr, W.H.2    Umesono, K.3
  • 6
    • 0033561797 scopus 로고    scopus 로고
    • Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
    • Melnick A, Licht JD: Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93:3167-3215, 1999
    • (1999) Blood , vol.93 , pp. 3167-3215
    • Melnick, A.1    Licht, J.D.2
  • 7
    • 0024519006 scopus 로고
    • Acute promyelocytic leukemia: Treatment results during a decade at Memorial Hospital
    • Cunningham I, Gee TS, Reich LM, et al: Acute promyelocytic leukemia: Treatment results during a decade at Memorial Hospital. Blood 73:1116-1122, 1989
    • (1989) Blood , vol.73 , pp. 1116-1122
    • Cunningham, I.1    Gee, T.S.2    Reich, L.M.3
  • 8
    • 0025836467 scopus 로고
    • Treatment of acute promyelocytic leukemia: A report on 70 cases
    • Fenaux P, Pollet J, Vandenbossche L, et al: Treatment of acute promyelocytic leukemia: A report on 70 cases. Leuk Lymphoma 4:249, 1991
    • (1991) Leuk Lymphoma , vol.4 , pp. 249
    • Fenaux, P.1    Pollet, J.2    Vandenbossche, L.3
  • 9
    • 0029131724 scopus 로고
    • Effect of aggressive daunomycin therapy on survival in acute promyelocytic leukemia
    • Head D, Kopecky KJ, Weick J, et al: Effect of aggressive daunomycin therapy on survival in acute promyelocytic leukemia. Blood 86:1717-1728, 1995
    • (1995) Blood , vol.86 , pp. 1717-1728
    • Head, D.1    Kopecky, K.J.2    Weick, J.3
  • 10
    • 0028569556 scopus 로고
    • Treatment outcome with chemotherapy in acute promyelocytic leukemia: The Southwest Oncology Group (SWOG) experience
    • suppl 2
    • Head DR, Kopecky KJ, Willman C, et al: Treatment outcome with chemotherapy in acute promyelocytic leukemia: The Southwest Oncology Group (SWOG) experience. Leukemia 8:S38-S41, 1994 (suppl 2)
    • (1994) Leukemia , vol.8
    • Head, D.R.1    Kopecky, K.J.2    Willman, C.3
  • 11
    • 0036838645 scopus 로고    scopus 로고
    • Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: Final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up
    • Avvisati G, Petti MC, Lo Coco F, et al: Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: Final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up. Blood 100:3141-3146, 2002
    • (2002) Blood , vol.100 , pp. 3141-3146
    • Avvisati, G.1    Petti, M.C.2    Lo Coco, F.3
  • 12
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • Huang ME, Ye YC, Chen SR, et al: Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72:567-572, 1988
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3
  • 13
    • 0025241453 scopus 로고
    • All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: Structure-function relationship
    • Chomienne C, Ballerini P, Balitrand N, et al: All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: Structure-function relationship. Blood 76:1710-1717, 1990
    • (1990) Blood , vol.76 , pp. 1710-1717
    • Chomienne, C.1    Ballerini, P.2    Balitrand, N.3
  • 14
    • 0025201879 scopus 로고
    • All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results
    • Castaigne S, Chomienne C, Daniel MT, et al: All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. Blood 76:1704-1709, 1990
    • (1990) Blood , vol.76 , pp. 1704-1709
    • Castaigne, S.1    Chomienne, C.2    Daniel, M.T.3
  • 15
    • 0025882306 scopus 로고
    • Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid)
    • Warrell RP Jr, Frankel SR, Miller WH Jr, et al: Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl J Med 324:1385-1393, 1991
    • (1991) N Engl J Med , vol.324 , pp. 1385-1393
    • Warrell Jr, R.P.1    Frankel, S.R.2    Miller Jr, W.H.3
  • 16
    • 0027368561 scopus 로고
    • Effect of all transretinoic acid in newly diagnosed acute promyelocytic leukemia: Results of a multicenter randomized trial - European APL 91 Group
    • Fenaux P, Le Deley MC, Castaigne S, et al: Effect of all transretinoic acid in newly diagnosed acute promyelocytic leukemia: Results of a multicenter randomized trial - European APL 91 Group. Blood 82:3241-3249, 1993
    • (1993) Blood , vol.82 , pp. 3241-3249
    • Fenaux, P.1    Le Deley, M.C.2    Castaigne, S.3
  • 17
    • 0030923479 scopus 로고    scopus 로고
    • All-trans-retinoic acid in acute promyelocytic leukemia
    • Tallman MS, Andersen JW, Schiffer CA, et al: All-trans-retinoic acid in acute promyelocytic leukemia. N Engl J Med 337:1021-1028, 1997
    • (1997) N Engl J Med , vol.337 , pp. 1021-1028
    • Tallman, M.S.1    Andersen, J.W.2    Schiffer, C.A.3
  • 18
    • 0033566639 scopus 로고    scopus 로고
    • A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia: The European APL Group
    • Fenaux P, Chastang C, Chevret S, et al: A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia: The European APL Group. Blood 94:1192-1200, 1999
    • (1999) Blood , vol.94 , pp. 1192-1200
    • Fenaux, P.1    Chastang, C.2    Chevret, S.3
  • 19
    • 13544263566 scopus 로고    scopus 로고
    • Outcome of acute promyelocytic leukemia treated with all trans retinoic acid and chemotherapy in elderly patients: The European group experience
    • Ades L, Chevret S, De Botton S, et al: Outcome of acute promyelocytic leukemia treated with all trans retinoic acid and chemotherapy in elderly patients: The European group experience. Leukemia 19:230-233, 2005
    • (2005) Leukemia , vol.19 , pp. 230-233
    • Ades, L.1    Chevret, S.2    De Botton, S.3
  • 20
    • 0031017173 scopus 로고    scopus 로고
    • Treatment of newly diagnosed acute promyelocytic leukemia without cytarabine
    • Estey E, Thall PF, Pierce S, et al: Treatment of newly diagnosed acute promyelocytic leukemia without cytarabine. J Clin Oncol 15:483-490, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 483-490
    • Estey, E.1    Thall, P.F.2    Pierce, S.3
  • 21
    • 10744220024 scopus 로고    scopus 로고
    • Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: A multicenter study by the PETHEMA group
    • Sanz MA, Martin G, Gonzalez M, et al: Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: A multicenter study by the PETHEMA group. Blood 103:1237-1243, 2004
    • (2004) Blood , vol.103 , pp. 1237-1243
    • Sanz, M.A.1    Martin, G.2    Gonzalez, M.3
  • 22
    • 0034663162 scopus 로고    scopus 로고
    • Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: A joint study of the PETHEMA and GIMEMA cooperative groups
    • Sanz MA, Lo Coco F, Martin G, et al: Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: A joint study of the PETHEMA and GIMEMA cooperative groups. Blood 96:1247-1253, 2000
    • (2000) Blood , vol.96 , pp. 1247-1253
    • Sanz, M.A.1    Lo Coco, F.2    Martin, G.3
  • 23
    • 0033230342 scopus 로고    scopus 로고
    • A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARalpha-positive acute promyelocytic leukemia: PETHEMA group
    • Sanz MA, Martin G, Rayon C, et al: A modified AIDA protocol with anthracycline-based consolidation results in high antileukemic efficacy and reduced toxicity in newly diagnosed PML/RARalpha-positive acute promyelocytic leukemia: PETHEMA group. Blood 94:3015-3021, 1999
    • (1999) Blood , vol.94 , pp. 3015-3021
    • Sanz, M.A.1    Martin, G.2    Rayon, C.3
  • 24
    • 0028008950 scopus 로고
    • All-trans retinoic acid for acute promyelocytic leukemia: Results of the New York Study
    • Frankel SR, Eardley A, Heller G, et al: All-trans retinoic acid for acute promyelocytic leukemia: Results of the New York Study. Ann Intern Med 120:278-286, 1994
    • (1994) Ann Intern Med , vol.120 , pp. 278-286
    • Frankel, S.R.1    Eardley, A.2    Heller, G.3
  • 25
    • 0032532009 scopus 로고    scopus 로고
    • Incidence, clinical features, and outcome of all trans-retinoic acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia: The European APL Group
    • De Botton S, Dombret H, Sanz M, et al: Incidence, clinical features, and outcome of all trans-retinoic acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia: The European APL Group. Blood 92:2712-2718, 1998
    • (1998) Blood , vol.92 , pp. 2712-2718
    • De Botton, S.1    Dombret, H.2    Sanz, M.3
  • 26
    • 0034950570 scopus 로고    scopus 로고
    • Variability in the levels of PML-RAR alpha fusion transcripts detected by the laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols
    • Bolufer P, Lo Coco F, Grimwade D, et al: Variability in the levels of PML-RAR alpha fusion transcripts detected by the laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols. Haematologica 86:570-576, 2001
    • (2001) Haematologica , vol.86 , pp. 570-576
    • Bolufer, P.1    Lo Coco, F.2    Grimwade, D.3
  • 27
    • 17044401059 scopus 로고    scopus 로고
    • Tricks of the trade for the appropriate management of newly diagnosed acute promyelocytic leukemia
    • Sanz MA, Tallman MS, Lo-Coco F: Tricks of the trade for the appropriate management of newly diagnosed acute promyelocytic leukemia. Blood 105:3019-3025, 2005
    • (2005) Blood , vol.105 , pp. 3019-3025
    • Sanz, M.A.1    Tallman, M.S.2    Lo-Coco, F.3
  • 28
    • 0033975927 scopus 로고    scopus 로고
    • Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR
    • Cassinat B, Zassadowski F, Balitrand N, et al: Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR. Leukemia 14:324-328, 2000
    • (2000) Leukemia , vol.14 , pp. 324-328
    • Cassinat, B.1    Zassadowski, F.2    Balitrand, N.3
  • 29
    • 0025890203 scopus 로고
    • Molecular evaluation of response to all-trans-retinoic acid therapy in patients with acute promyelocytic leukemia
    • Lo Coco F, Avvisati G, Diverio D, et al: Molecular evaluation of response to all-trans-retinoic acid therapy in patients with acute promyelocytic leukemia. Blood 77:1657-1659, 1991
    • (1991) Blood , vol.77 , pp. 1657-1659
    • Lo Coco, F.1    Avvisati, G.2    Diverio, D.3
  • 30
    • 0025261428 scopus 로고
    • Report of the national cancer institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia
    • Cheson B, Cassileth P, Head D, et al: Report of the national cancer institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia. J Clin Oncol 8:813-819, 1990
    • (1990) J Clin Oncol , vol.8 , pp. 813-819
    • Cheson, B.1    Cassileth, P.2    Head, D.3
  • 31
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observation
    • Kaplan E, Meier P: Nonparametric estimation from incomplete observation. J Am Stat Assoc 53:457-481, 1958
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 32
    • 0000957062 scopus 로고
    • Asymptotically efficient rank invariant test procedures
    • Peto R, Peto J: Asymptotically efficient rank invariant test procedures. J R Stat Soc A 135:185-198, 1972
    • (1972) J R Stat Soc A , vol.135 , pp. 185-198
    • Peto, R.1    Peto, J.2
  • 33
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR: Regression models and life tables. J R Stat Soc B 34:187-220, 1972
    • (1972) J R Stat Soc B , vol.34 , pp. 187-220
    • Cox, D.R.1
  • 34
    • 0000120995 scopus 로고    scopus 로고
    • A class of k-sample tests for comparing the cumulative incidence of a competing risk
    • Gray R: A class of k-sample tests for comparing the cumulative incidence of a competing risk. Ann Stat 16:1141-1154, 1998
    • (1998) Ann Stat , vol.16 , pp. 1141-1154
    • Gray, R.1
  • 35
    • 1542532754 scopus 로고    scopus 로고
    • A proportional hazards model for the subdistribution of a competing risk
    • Fine J, Gray R: A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94:496-509, 1999
    • (1999) J Am Stat Assoc , vol.94 , pp. 496-509
    • Fine, J.1    Gray, R.2
  • 36
    • 9444297295 scopus 로고    scopus 로고
    • All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia
    • Sanz MA, Vellenga E, Rayon C, et al: All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia. Blood 104:3490-3493, 2004
    • (2004) Blood , vol.104 , pp. 3490-3493
    • Sanz, M.A.1    Vellenga, E.2    Rayon, C.3
  • 37
    • 0035077367 scopus 로고    scopus 로고
    • Idarubicin improves blast cell clearance during induction therapy in children AML: Results of study AML-BFM 93 - AML-BFM study group
    • Creutzig U, Ritter J, Zimmermann M, et al: Idarubicin improves blast cell clearance during induction therapy in children AML: Results of study AML-BFM 93 - AML-BFM study group. Leukemia 15:348-354, 2001
    • (2001) Leukemia , vol.15 , pp. 348-354
    • Creutzig, U.1    Ritter, J.2    Zimmermann, M.3
  • 38
    • 0026586008 scopus 로고
    • Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia
    • Wiernik P, Banks P, Case D, et al: Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia. Blood 79:313-319, 1992
    • (1992) Blood , vol.79 , pp. 313-319
    • Wiernik, P.1    Banks, P.2    Case, D.3
  • 39
    • 0026650021 scopus 로고
    • A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: A Southeastern Cancer Study Group study
    • Volger W, Velez-Garcia E, Weiner R, et al: A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: A Southeastern Cancer Study Group study. J Clin Oncol 10:1103-1111, 1992
    • (1992) J Clin Oncol , vol.10 , pp. 1103-1111
    • Volger, W.1    Velez-Garcia, E.2    Weiner, R.3
  • 40
    • 0019171436 scopus 로고
    • Antileukemic activity of 4-demethoxydaunorubicin in mice
    • Casazza AM, Pratesi G, Giuliani F, et al: Antileukemic activity of 4-demethoxydaunorubicin in mice. Tumori 66:549-564, 1980
    • (1980) Tumori , vol.66 , pp. 549-564
    • Casazza, A.M.1    Pratesi, G.2    Giuliani, F.3
  • 41
    • 16544385074 scopus 로고    scopus 로고
    • Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: Final induction results of Cancer and Leukemia Group B Study 9621
    • Kolitz JE, George SL, Dodge RK, et al: Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: Final induction results of Cancer and Leukemia Group B Study 9621. J Clin Oncol 22:4290-4301, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 4290-4301
    • Kolitz, J.E.1    George, S.L.2    Dodge, R.K.3
  • 42
    • 0033858433 scopus 로고    scopus 로고
    • Double induction strategy including high dose cytarabine in combination with all-trans retinoic acid: Effects in patients with newly diagnosed acute promyelocytic leukemia - German AML Cooperative Group
    • Lengfelder E, Reichert A, Schoch C, et al: Double induction strategy including high dose cytarabine in combination with all-trans retinoic acid: Effects in patients with newly diagnosed acute promyelocytic leukemia - German AML Cooperative Group. Leukemia 14:1362-1370, 2000
    • (2000) Leukemia , vol.14 , pp. 1362-1370
    • Lengfelder, E.1    Reichert, A.2    Schoch, C.3
  • 43
    • 11144355810 scopus 로고    scopus 로고
    • All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia
    • Shen ZX, Shi ZZ, Fang J, et al: All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci U S A 101: 5328-5335, 2004
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5328-5335
    • Shen, Z.X.1    Shi, Z.Z.2    Fang, J.3
  • 44
    • 0032487923 scopus 로고    scopus 로고
    • Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
    • Soignet SL, Maslak P, Wang ZG, et al: Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N Engl J Med 339:1341-1348, 1998
    • (1998) N Engl J Med , vol.339 , pp. 1341-1348
    • Soignet, S.L.1    Maslak, P.2    Wang, Z.G.3
  • 45
    • 0037811741 scopus 로고    scopus 로고
    • Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia
    • Raffoux E, Rousselot P, Poupon J, et al: Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia. J Clin Oncol 21:2326-2334, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 2326-2334
    • Raffoux, E.1    Rousselot, P.2    Poupon, J.3
  • 46
    • 33646386643 scopus 로고    scopus 로고
    • Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia
    • Estey E, Garcia-Manero G, Ferrajoli A, et al: Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia. Blood 107:3469-3473, 2006
    • (2006) Blood , vol.107 , pp. 3469-3473
    • Estey, E.1    Garcia-Manero, G.2    Ferrajoli, A.3
  • 47
    • 33645498328 scopus 로고    scopus 로고
    • Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: Durable remissions with minimal toxicity
    • Mathews V, George B, Lakshmi K, et al: Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: Durable remissions with minimal toxicity. Blood 107: 2627-2632, 2006
    • (2006) Blood , vol.107 , pp. 2627-2632
    • Mathews, V.1    George, B.2    Lakshmi, K.3
  • 48
    • 29844442869 scopus 로고    scopus 로고
    • Treatment of acute promyelocytic leukemia with arsenic trioxide without ATRA and/or chemotherapy
    • Gavamzadeh A, Alimoghaddam K, Ghaffari S, et al: Treatment of acute promyelocytic leukemia with arsenic trioxide without ATRA and/or chemotherapy. Ann Oncol 17:131-134, 2006
    • (2006) Ann Oncol , vol.17 , pp. 131-134
    • Gavamzadeh, A.1    Alimoghaddam, K.2    Ghaffari, S.3
  • 49
    • 33644976445 scopus 로고    scopus 로고
    • Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy
    • de Botton S, Sanz M, Chevret S, et al: Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy. Leukemia 20:35-41, 2006
    • (2006) Leukemia , vol.20 , pp. 35-41
    • de Botton, S.1    Sanz, M.2    Chevret, S.3


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