Mutator mutations enhance tumorigenic efficiency across fitness landscapes

PLoS ONE

Volumn 4, Issue 6, 2009, Pages

  Beckman, Robert A ^a  

^a INSTITUTE FOR ADVANCED STUDY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ONCOPROTEIN; PROTEIN KINASE INHIBITOR;

ARTICLE; CARCINOGENESIS; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC STABILITY; HYPOTHESIS; MALIGNANT NEOPLASTIC DISEASE; MALIGNANT TRANSFORMATION; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; PRECANCER; PROGNOSIS; TUMOR GROWTH; ANIMAL; BACTERIAL GENE; BACTERIAL PHENOMENA AND FUNCTIONS; BIOLOGICAL MODEL; ENVIRONMENT; GENETIC PREDISPOSITION; GENETICS; HUMAN; MOUSE; MUTATION; NEOPLASM; PHENOTYPE; PROBABILITY; STATISTICAL MODEL; THEORETICAL MODEL;

BACTERIA (MICROORGANISMS);

ANIMALS; BACTERIAL PHYSIOLOGICAL PHENOMENA; ENVIRONMENT; GENES, BACTERIAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICE; MODELS, GENETIC; MODELS, STATISTICAL; MODELS, THEORETICAL; MUTATION; NEOPLASMS; PHENOTYPE; PROBABILITY;

EID: 67649183495     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005860     Document Type: Article

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