Genetic instability in cancer: Theory and experiment

Seminars in Cancer Biology

Volumn 15, Issue 6, 2005, Pages 423-435

  Beckman, Robert A ^a,c   Loeb, Lawrence A ^b  

^a CENTOCOR INC   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

Cancer; Genetic instability; Mathematical models; Mutator hypothesis; Theory

Indexed keywords

DNA POLYMERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

CANCER CELL; CANCER GROWTH; CARCINOGENESIS; CELL CYCLE; CHROMOSOMAL INSTABILITY; DATA ANALYSIS; DISEASE COURSE; GENE MUTATION; GENETIC STABILITY; HUMAN; MATHEMATICAL ANALYSIS; MOLECULAR BIOLOGY; REVIEW; STEM CELL; STOCHASTIC MODEL; WILD TYPE;

CELL TRANSFORMATION, NEOPLASTIC; GENOMIC INSTABILITY; HUMANS; NEOPLASMS;

EID: 24944546620     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcancer.2005.06.007     Document Type: Review

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