메뉴 건너뛰기




Volumn 100, Issue 4, 2009, Pages 654-662

Up-regulated expression of ADAM17 in gastrointestinal stromal tumors: Coexpression with EGFR and EGFR ligands

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; ADAM10 PROTEIN; ADAM17 PROTEIN; ADAM9 PROTEIN; AMPHIREGULIN; BETACELLULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIREGULIN; GELATINASE A; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; METALLOPROTEINASE; STEM CELL FACTOR RECEPTOR; UNCLASSIFIED DRUG; DISINTEGRIN; LIGAND; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

EID: 67449099151     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2009.01089.x     Document Type: Article
Times cited : (25)

References (46)
  • 1
    • 0035142836 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors -definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001; 438: 1-12.
    • (2001) Virchows Arch , vol.438 , pp. 1-12
    • Miettinen, M.1    Lasota, J.2
  • 2
    • 0036301722 scopus 로고    scopus 로고
    • Diagnosis of gastrointestinal stromal tumors: A consensus approach
    • Fletcher CD, Berman JJ, Corless C et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002; 33: 459-65.
    • (2002) Hum Pathol , vol.33 , pp. 459-465
    • Fletcher, C.D.1    Berman, J.J.2    Corless, C.3
  • 3
    • 15644363454 scopus 로고    scopus 로고
    • Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
    • Hirota S, Isozaki K, Moriyama Y et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998; 279: 577-80.
    • (1998) Science , vol.279 , pp. 577-580
    • Hirota, S.1    Isozaki, K.2    Moriyama, Y.3
  • 4
    • 33749459756 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis, and differential diagnosis
    • Miettinen M, Lasota J. Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Laboratory Med 2006; 130: 1466-78.
    • (2006) Arch Pathol Laboratory Med , vol.130 , pp. 1466-1478
    • Miettinen, M.1    Lasota, J.2
  • 5
    • 0242670019 scopus 로고    scopus 로고
    • PDGFRA activating mutations in gastrointestinal stromal tumors
    • Heinrich MC, Corless CL, Duensing A et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003; 299: 708-10.
    • (2003) Science , vol.299 , pp. 708-710
    • Heinrich, M.C.1    Corless, C.L.2    Duensing, A.3
  • 6
    • 0041971080 scopus 로고    scopus 로고
    • Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors
    • Hirota S, Ohashi A, Nishida T et al. Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors. Gastroenterology 2003; 125: 660-7.
    • (2003) Gastroenterology , vol.125 , pp. 660-667
    • Hirota, S.1    Ohashi, A.2    Nishida, T.3
  • 7
    • 0036769721 scopus 로고    scopus 로고
    • Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: A report of the EORTC Soft Tissue and Bone Sarcoma Group
    • van Oosterom AT, Judson IR, Verweij J et al. Update of phase I study of imatinib (STI571) in advanced soft tissue sarcomas and gastrointestinal stromal tumors: A report of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer 2002; 38 (Suppl 5): S83-7.
    • (2002) Eur J Cancer , vol.38 , Issue.SUPPL. 5
    • van Oosterom, A.T.1    Judson, I.R.2    Verweij, J.3
  • 9
    • 20344393896 scopus 로고    scopus 로고
    • Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation
    • Antonescu CR, Besmer P, Guo T et al. Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clin Cancer Res 2005; 11: 4182-90.
    • (2005) Clin Cancer Res , vol.11 , pp. 4182-4190
    • Antonescu, C.R.1    Besmer, P.2    Guo, T.3
  • 10
    • 33750595859 scopus 로고    scopus 로고
    • Molecular correlates of imatinib resistance in gastrointestinal stromal tumors
    • Heinrich MC, Corless CL, Blanke CD et al. Molecular correlates of imatinib resistance in gastrointestinal stromal tumors. J Clin Oncol 2006; 24: 4764-74.
    • (2006) J Clin Oncol , vol.24 , pp. 4764-4774
    • Heinrich, M.C.1    Corless, C.L.2    Blanke, C.D.3
  • 11
    • 34147105872 scopus 로고    scopus 로고
    • ADAMs in cancer cell proliferation and progression
    • Mochizuki S, Okada Y. ADAMs in cancer cell proliferation and progression. Cancer Sci 2007; 98: 621-8.
    • (2007) Cancer Sci , vol.98 , pp. 621-628
    • Mochizuki, S.1    Okada, Y.2
  • 12
    • 8044250278 scopus 로고    scopus 로고
    • Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha
    • Moss ML, Jin SL, Milla ME et al. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 1997; 385: 733-6.
    • (1997) Nature , vol.385 , pp. 733-736
    • Moss, M.L.1    Jin, S.L.2    Milla, M.E.3
  • 13
    • 0037066757 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability
    • Sunnarborg SW, Hinkle CL, Stevenson M et al. Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability. J Biol Chem 2002; 277: 12838-45.
    • (2002) J Biol Chem , vol.277 , pp. 12838-12845
    • Sunnarborg, S.W.1    Hinkle, C.L.2    Stevenson, M.3
  • 14
    • 2642541715 scopus 로고    scopus 로고
    • Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: The juxtamembrane stalk determines cleavage efficiency
    • Hinkle CL, Sunnarborg SW, Loiselle D et al. Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: The juxtamembrane stalk determines cleavage efficiency. J Biol Chem 2004; 279: 24179-88.
    • (2004) J Biol Chem , vol.279 , pp. 24179-24188
    • Hinkle, C.L.1    Sunnarborg, S.W.2    Loiselle, D.3
  • 15
    • 0029025332 scopus 로고
    • Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas
    • Wikstrand CJ, Hale LP, Batra SK et al. Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. Cancer Res 1995; 55: 3140-8.
    • (1995) Cancer Res , vol.55 , pp. 3140-3148
    • Wikstrand, C.J.1    Hale, L.P.2    Batra, S.K.3
  • 16
    • 0035839427 scopus 로고    scopus 로고
    • A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor
    • Umata T, Hirata M, Takahashi T et al. A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor. J Biol Chem 2001; 276: 30475-82.
    • (2001) J Biol Chem , vol.276 , pp. 30475-30482
    • Umata, T.1    Hirata, M.2    Takahashi, T.3
  • 17
    • 0032479422 scopus 로고    scopus 로고
    • Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a metalloprotease inhibitor. Release of a predominant N-glycosylated 43-kDa soluble form
    • Brown CL, Meise KS, Plowman GD, Coffey RJ, Dempsey PJ. Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a metalloprotease inhibitor. Release of a predominant N-glycosylated 43-kDa soluble form. J Biol Chem 1998; 273: 17258-68.
    • (1998) J Biol Chem , vol.273 , pp. 17258-17268
    • Brown, C.L.1    Meise, K.S.2    Plowman, G.D.3    Coffey, R.J.4    Dempsey, P.J.5
  • 18
    • 0034714890 scopus 로고    scopus 로고
    • The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone
    • McCulloch DR, Harvey M, Herington AC. The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone. Mol Cell Endocrinol 2000; 167: 11-21.
    • (2000) Mol Cell Endocrinol , vol.167 , pp. 11-21
    • McCulloch, D.R.1    Harvey, M.2    Herington, A.C.3
  • 19
    • 0036467793 scopus 로고    scopus 로고
    • ADAMs (a disintegrin and metalloproteinase) messenger RNA expression in Helicobacter pylori-infected, normal, and neoplastic gastric mucosa
    • Yoshimura T, Tomita T, Dixon MF, Axon AT, Robinson PA, Crabtree JE. ADAMs (a disintegrin and metalloproteinase) messenger RNA expression in Helicobacter pylori-infected, normal, and neoplastic gastric mucosa. J Infect Dis 2002; 185: 332-40.
    • (2002) J Infect Dis , vol.185 , pp. 332-340
    • Yoshimura, T.1    Tomita, T.2    Dixon, M.F.3    Axon, A.T.4    Robinson, P.A.5    Crabtree, J.E.6
  • 20
    • 0038581051 scopus 로고    scopus 로고
    • TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
    • Gschwind A, Hart S, Fischer OM, Ullrich A. TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. Embo J 2003; 22: 2411-21.
    • (2003) Embo J , vol.22 , pp. 2411-2421
    • Gschwind, A.1    Hart, S.2    Fischer, O.M.3    Ullrich, A.4
  • 21
    • 27644466636 scopus 로고    scopus 로고
    • Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer
    • Tanaka Y, Miyamoto S, Suzuki SO et al. Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer. Clin Cancer Res 2005; 11: 4783-92.
    • (2005) Clin Cancer Res , vol.11 , pp. 4783-4792
    • Tanaka, Y.1    Miyamoto, S.2    Suzuki, S.O.3
  • 22
    • 0032515018 scopus 로고    scopus 로고
    • An essential role for ectodomain shedding in mammalian development
    • Peschon JJ, Slack JL, Reddy P et al. An essential role for ectodomain shedding in mammalian development. Science 1998; 282: 1281-4.
    • (1998) Science , vol.282 , pp. 1281-1284
    • Peschon, J.J.1    Slack, J.L.2    Reddy, P.3
  • 23
    • 0027315183 scopus 로고
    • Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation
    • Mann GB, Fowler KJ, Gabriel A, Nice EC, Williams RL, Dunn AR. Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 1993; 73: 249-61.
    • (1993) Cell , vol.73 , pp. 249-261
    • Mann, G.B.1    Fowler, K.J.2    Gabriel, A.3    Nice, E.C.4    Williams, R.L.5    Dunn, A.R.6
  • 24
    • 0029064203 scopus 로고
    • Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
    • Threadgill DW, Dlugosz AA, Hansen LA et al. Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype. Science 1995; 269: 230-4.
    • (1995) Science , vol.269 , pp. 230-234
    • Threadgill, D.W.1    Dlugosz, A.A.2    Hansen, L.A.3
  • 25
    • 32044464123 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) signaling in cancer
    • Normanno N, De Luca A, Bianco C et al. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 2006; 366: 2-16.
    • (2006) Gene , vol.366 , pp. 2-16
    • Normanno, N.1    De Luca, A.2    Bianco, C.3
  • 26
    • 0032780384 scopus 로고    scopus 로고
    • Expression of transforming growth factor-alpha and epidermal growth factor receptor in gastrointestinal stromal tumours
    • Cai YC, Jiang Z, Vittimberga F et al. Expression of transforming growth factor-alpha and epidermal growth factor receptor in gastrointestinal stromal tumours. Virchows Arch 1999; 435: 112-15.
    • (1999) Virchows Arch , vol.435 , pp. 112-115
    • Cai, Y.C.1    Jiang, Z.2    Vittimberga, F.3
  • 27
    • 34547935983 scopus 로고    scopus 로고
    • EGFR and gastrointestinal stromal tumor. an immunohistochemical and FISH study of 82 cases
    • Lopes LF, Bacchi CE. EGFR and gastrointestinal stromal tumor. an immunohistochemical and FISH study of 82 cases. Mod Pathol 2007; 20: 990-4.
    • (2007) Mod Pathol , vol.20 , pp. 990-994
    • Lopes, L.F.1    Bacchi, C.E.2
  • 28
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995; 19: 183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 29
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • Prenzel N, Zwick E, Daub H et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999; 402: 884-8.
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3
  • 30
    • 0026720594 scopus 로고
    • Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon
    • Johnson GR, Saeki T, Gordon AW, Shoyab M, Salomon DS, Stromberg K. Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon. J Cell Biol 1992; 118: 741-51.
    • (1992) J Cell Biol , vol.118 , pp. 741-751
    • Johnson, G.R.1    Saeki, T.2    Gordon, A.W.3    Shoyab, M.4    Salomon, D.S.5    Stromberg, K.6
  • 31
    • 0030740155 scopus 로고    scopus 로고
    • Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy
    • Funatomi H, Itakura J, Ishiwata T et al. Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy. Int J Cancer 1997; 72: 512-17.
    • (1997) Int J Cancer , vol.72 , pp. 512-517
    • Funatomi, H.1    Itakura, J.2    Ishiwata, T.3
  • 32
    • 33745714256 scopus 로고    scopus 로고
    • Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells
    • Castillo J, Erroba E, Perugorria MJ et al. Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells. Cancer Res 2006; 66: 6129-38.
    • (2006) Cancer Res , vol.66 , pp. 6129-6138
    • Castillo, J.1    Erroba, E.2    Perugorria, M.J.3
  • 33
    • 0027942871 scopus 로고
    • Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma
    • Inui Y, Higashiyama S, Kawata S et al. Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma. Gastroenterology 1994; 107: 1799-804.
    • (1994) Gastroenterology , vol.107 , pp. 1799-1804
    • Inui, Y.1    Higashiyama, S.2    Kawata, S.3
  • 35
    • 0035020573 scopus 로고    scopus 로고
    • Bimodal expression of heparin-binding EGF-like growth factor in colonic neoplasms
    • Ito Y, Higashiyama S, Takeda T, Okada M, Matsuura N. Bimodal expression of heparin-binding EGF-like growth factor in colonic neoplasms. Anticancer Res 2001; 21: 1391-4.
    • (2001) Anticancer Res , vol.21 , pp. 1391-1394
    • Ito, Y.1    Higashiyama, S.2    Takeda, T.3    Okada, M.4    Matsuura, N.5
  • 36
    • 0025266694 scopus 로고
    • The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity
    • Plowman GD, Green JM, McDonald VL et al. The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity. Mol Cell Biol 1990; 10: 1969-81.
    • (1990) Mol Cell Biol , vol.10 , pp. 1969-1981
    • Plowman, G.D.1    Green, J.M.2    McDonald, V.L.3
  • 37
    • 0030888746 scopus 로고    scopus 로고
    • Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells
    • Kondapaka SB, Fridman R, Reddy KB. Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells. Int J Cancer 1997; 70: 722-6.
    • (1997) Int J Cancer , vol.70 , pp. 722-726
    • Kondapaka, S.B.1    Fridman, R.2    Reddy, K.B.3
  • 38
    • 0037416187 scopus 로고    scopus 로고
    • TACE is required for the activation of the EGFR by TGF-alpha in tumors
    • Borrell-Pages M, Rojo F, Albanell J, Baselga J, Arribas J. TACE is required for the activation of the EGFR by TGF-alpha in tumors. Embo J 2003; 22: 1114-24.
    • (2003) Embo J , vol.22 , pp. 1114-1124
    • Borrell-Pages, M.1    Rojo, F.2    Albanell, J.3    Baselga, J.4    Arribas, J.5
  • 39
    • 7244238000 scopus 로고    scopus 로고
    • ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor
    • Kodama T, Ikeda E, Okada A et al. ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor. Am J Pathol 2004; 165: 1743-53.
    • (2004) Am J Pathol , vol.165 , pp. 1743-1753
    • Kodama, T.1    Ikeda, E.2    Okada, A.3
  • 40
    • 0029970330 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinases following cellular transformation
    • Grant GM, Cobb JK, Castillo B, Klebe RJ. Regulation of matrix metalloproteinases following cellular transformation. J Cell Physiol 1996; 167: 177-83.
    • (1996) J Cell Physiol , vol.167 , pp. 177-183
    • Grant, G.M.1    Cobb, J.K.2    Castillo, B.3    Klebe, R.J.4
  • 41
    • 0029836015 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7 expression in gastric carcinoma
    • Honda M, Mori M, Ueo H, Sugimachi K, Akiyoshi T. Matrix metalloproteinase-7 expression in gastric carcinoma. Gut 1996; 39: 444-8.
    • (1996) Gut , vol.39 , pp. 444-448
    • Honda, M.1    Mori, M.2    Ueo, H.3    Sugimachi, K.4    Akiyoshi, T.5
  • 42
    • 0031855699 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors
    • Lampert K, Machein U, Machein MR, Conca W, Peter HH, Volk B. Expression of matrix metalloproteinases and their tissue inhibitors in human brain tumors. Am J Pathol 1998; 153: 429-37.
    • (1998) Am J Pathol , vol.153 , pp. 429-437
    • Lampert, K.1    Machein, U.2    Machein, M.R.3    Conca, W.4    Peter, H.H.5    Volk, B.6
  • 43
    • 0032959030 scopus 로고    scopus 로고
    • Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors
    • Nakada M, Nakamura H, Ikeda E et al. Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors. Am J Pathol 1999; 154: 417-28.
    • (1999) Am J Pathol , vol.154 , pp. 417-428
    • Nakada, M.1    Nakamura, H.2    Ikeda, E.3
  • 44
    • 0033304670 scopus 로고    scopus 로고
    • Amphiregulin is coordinately expressed with heparin-binding epidermal growth factor-like growth factor in the interstitial smooth muscle of the human prostate
    • Adam RM, Borer JG, Williams J, Eastham JA, Loughlin KR, Freeman MR. Amphiregulin is coordinately expressed with heparin-binding epidermal growth factor-like growth factor in the interstitial smooth muscle of the human prostate. Endocrinology 1999; 140: 5866-75.
    • (1999) Endocrinology , vol.140 , pp. 5866-5875
    • Adam, R.M.1    Borer, J.G.2    Williams, J.3    Eastham, J.A.4    Loughlin, K.R.5    Freeman, M.R.6
  • 45
    • 34447576577 scopus 로고    scopus 로고
    • Imatinib mesylate inhibits cell invasion of malignant peripheral nerve sheath tumor induced by platelet-derived growth factor-BB
    • Aoki M, Nabeshima K, Koga K et al. Imatinib mesylate inhibits cell invasion of malignant peripheral nerve sheath tumor induced by platelet-derived growth factor-BB. Laboratory Invest 2007; 87: 767-79.
    • (2007) Laboratory Invest , vol.87 , pp. 767-779
    • Aoki, M.1    Nabeshima, K.2    Koga, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.