메뉴 건너뛰기




Volumn 20, Issue 9, 2007, Pages 990-994

EGFR and gastrointestinal stromal tumor: An immunohistochemical and FISH study of 82 cases

Author keywords

Epidermal growth factor receptor; Fluorescence in situ hybridization; Gastrointestinal stromal tumor; Immunohistochemistry; KIT; Tissue microarray

Indexed keywords

CD34 ANTIGEN; EOSIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HEMATOXYLIN; STEM CELL FACTOR RECEPTOR;

EID: 34547935983     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.3800932     Document Type: Article
Times cited : (20)

References (35)
  • 1
    • 33645092405 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours: An update
    • Rubin BP. Gastrointestinal stromal tumours: an update. Histopathology 2006;48:83-96.
    • (2006) Histopathology , vol.48 , pp. 83-96
    • Rubin, B.P.1
  • 2
    • 33749459756 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours. Review on morphology, molecular pathology, prognosis, and differential diagnosis
    • Miettinen M, Lasota J. Gastrointestinal stromal tumours. Review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med 2006;130:1466-1478.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 1466-1478
    • Miettinen, M.1    Lasota, J.2
  • 3
    • 15644363454 scopus 로고    scopus 로고
    • Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
    • Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998;279:577-580.
    • (1998) Science , vol.279 , pp. 577-580
    • Hirota, S.1    Isozaki, K.2    Moriyama, Y.3
  • 5
    • 0036092268 scopus 로고    scopus 로고
    • KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size
    • Corless CL, McGreevey L, Haley A, Town A, Heinrich MC. KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size. Am J Pathol 2002;160:1567-1572.
    • (2002) Am J Pathol , vol.160 , pp. 1567-1572
    • Corless, C.L.1    McGreevey, L.2    Haley, A.3    Town, A.4    Heinrich, M.C.5
  • 6
    • 0242670019 scopus 로고    scopus 로고
    • PDGFRA activating mutations in gastrointestinal stromal tumors
    • Heinrich MC, Corless CL, Duensing A, et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003;299:708-710.
    • (2003) Science , vol.299 , pp. 708-710
    • Heinrich, M.C.1    Corless, C.L.2    Duensing, A.3
  • 7
    • 0037186924 scopus 로고    scopus 로고
    • Imatinib mesylate - a new oral targeted therapy
    • Savage DG, Antman KH. Imatinib mesylate - a new oral targeted therapy. N Engl J Med 2002;346:683-693.
    • (2002) N Engl J Med , vol.346 , pp. 683-693
    • Savage, D.G.1    Antman, K.H.2
  • 8
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 9
    • 27244451321 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
    • Takano T, Ohe Y, Sakamoto H, et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005;23:6829-6837.
    • (2005) J Clin Oncol , vol.23 , pp. 6829-6837
    • Takano, T.1    Ohe, Y.2    Sakamoto, H.3
  • 10
    • 0142119289 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in non-small-cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
    • Hirsch FR, Varella-Garcia M, Bunn Jr PA, et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003;21:3798-3807.
    • (2003) J Clin Oncol , vol.21 , pp. 3798-3807
    • Hirsch, F.R.1    Varella-Garcia, M.2    Bunn Jr, P.A.3
  • 11
    • 0032780384 scopus 로고    scopus 로고
    • Expression of transforming growth factor-alpha and epidermal growth factor receptor in gastrointestinal stromal tumours
    • Cai YC, Jiang Z, Vittimberga F, et al. Expression of transforming growth factor-alpha and epidermal growth factor receptor in gastrointestinal stromal tumours. Virchows Arch 1999;435:112-115.
    • (1999) Virchows Arch , vol.435 , pp. 112-115
    • Cai, Y.C.1    Jiang, Z.2    Vittimberga, F.3
  • 12
    • 31144451379 scopus 로고    scopus 로고
    • About a case of GIST occurring during pregnancy with immunohistochemical expression of epidermal growth factor receptor and progesterone receptor
    • Lanzafame S, Minutolo V, Caltabiano R, et al. About a case of GIST occurring during pregnancy with immunohistochemical expression of epidermal growth factor receptor and progesterone receptor. Pathol Res Pract 2006;202:119-123.
    • (2006) Pathol Res Pract , vol.202 , pp. 119-123
    • Lanzafame, S.1    Minutolo, V.2    Caltabiano, R.3
  • 13
    • 34547957371 scopus 로고    scopus 로고
    • Mutational analysis of the epidermal growth factor receptor gene in gastrointestinal stromal tumors
    • Yoo NJ, Lee JW, Soung YH, et al. Mutational analysis of the epidermal growth factor receptor gene in gastrointestinal stromal tumors. J Korean Gastric Cancer Assoc 2004;4:268-271.
    • (2004) J Korean Gastric Cancer Assoc , vol.4 , pp. 268-271
    • Yoo, N.J.1    Lee, J.W.2    Soung, Y.H.3
  • 14
    • 33645301012 scopus 로고    scopus 로고
    • Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma
    • Bode B, Frigerio S, Behnke S, et al. Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma. Mod Pathol 2006;19:541-547.
    • (2006) Mod Pathol , vol.19 , pp. 541-547
    • Bode, B.1    Frigerio, S.2    Behnke, S.3
  • 15
    • 33748653109 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas
    • Chung CH, Ely K, McGavran L, et al. Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas. J Clin Oncol 2006;24:4170-4176.
    • (2006) J Clin Oncol , vol.24 , pp. 4170-4176
    • Chung, C.H.1    Ely, K.2    McGavran, L.3
  • 16
    • 33645322927 scopus 로고    scopus 로고
    • Epithelial growth factor receptor status in primary and recurrent ovarian cancer
    • Stadlmann S, Gueth U, Reiser U, et al. Epithelial growth factor receptor status in primary and recurrent ovarian cancer. Mod Pathol 2006;19:607-610.
    • (2006) Mod Pathol , vol.19 , pp. 607-610
    • Stadlmann, S.1    Gueth, U.2    Reiser, U.3
  • 17
    • 33645164077 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: Prognostic significance and relationship to other prognostic factors
    • Layfield LJ, Willmore C, Tripp S, et al. Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: prognostic significance and relationship to other prognostic factors. Appl Immunohistochem Mol Morphol 2006;14:91-96.
    • (2006) Appl Immunohistochem Mol Morphol , vol.14 , pp. 91-96
    • Layfield, L.J.1    Willmore, C.2    Tripp, S.3
  • 18
    • 32844457996 scopus 로고    scopus 로고
    • Amplifications of the epidermal growth factor receptor gene (EGFR) are common in phyllodes tumors of the breast and are associated with tumor progression
    • Kersting C, Kuijper A, Schmidt H, et al. Amplifications of the epidermal growth factor receptor gene (EGFR) are common in phyllodes tumors of the breast and are associated with tumor progression. Lab Invest 2006;86:54-61.
    • (2006) Lab Invest , vol.86 , pp. 54-61
    • Kersting, C.1    Kuijper, A.2    Schmidt, H.3
  • 19
    • 31844432805 scopus 로고    scopus 로고
    • EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus
    • Hanawa M, Suzuki S, Dobashi Y, et al. EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus. Int J Cancer 2006;118:1173-1180.
    • (2006) Int J Cancer , vol.118 , pp. 1173-1180
    • Hanawa, M.1    Suzuki, S.2    Dobashi, Y.3
  • 20
    • 0028225146 scopus 로고
    • Epidermal-growth-factor-receptor expression is associated with rapid tumor proliferation in bladder cancer
    • Sauter G, Haley J, Chew K, et al. Epidermal-growth-factor-receptor expression is associated with rapid tumor proliferation in bladder cancer. Int J Cancer 1994;57:508-514.
    • (1994) Int J Cancer , vol.57 , pp. 508-514
    • Sauter, G.1    Haley, J.2    Chew, K.3
  • 21
    • 31644433069 scopus 로고    scopus 로고
    • An update on the role of epidermal growth factor receptor inhibitors in non-small cell lung cancer
    • Edelman MJ. An update on the role of epidermal growth factor receptor inhibitors in non-small cell lung cancer. Semin Oncol 2005;32:S3-S8.
    • (2005) Semin Oncol , vol.32
    • Edelman, M.J.1
  • 22
    • 10344230403 scopus 로고    scopus 로고
    • Aberration of epidermal growth factor receptor expression in bone and soft-tissue tumors: Protein overexpression, gene amplification and activation of downstream molecules
    • Dobashi Y, Takei N, Suzuki S, et al. Aberration of epidermal growth factor receptor expression in bone and soft-tissue tumors: protein overexpression, gene amplification and activation of downstream molecules. Mod Pathol 2004;17:1497-1505.
    • (2004) Mod Pathol , vol.17 , pp. 1497-1505
    • Dobashi, Y.1    Takei, N.2    Suzuki, S.3
  • 23
    • 13444291031 scopus 로고    scopus 로고
    • Expression of receptor tyrosine kinases epidermal growth factor receptor and HER-2/neu in synovial sarcoma
    • Thomas DG, Giordano TJ, Sanders D, et al. Expression of receptor tyrosine kinases epidermal growth factor receptor and HER-2/neu in synovial sarcoma. Cancer 2005;103:830-838.
    • (2005) Cancer , vol.103 , pp. 830-838
    • Thomas, D.G.1    Giordano, T.J.2    Sanders, D.3
  • 24
    • 33747598681 scopus 로고    scopus 로고
    • Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma
    • Ganti R, Skapek SX, Zhang J, et al. Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma. Mod Pathol 2006;19:1213-1220.
    • (2006) Mod Pathol , vol.19 , pp. 1213-1220
    • Ganti, R.1    Skapek, S.X.2    Zhang, J.3
  • 25
    • 33646492502 scopus 로고    scopus 로고
    • Expression of HER1/EGFR protein in human soft tissue sarcomas
    • Yang JL, Hannan MT, Russell PJ, et al. Expression of HER1/EGFR protein in human soft tissue sarcomas. Eur J Surg Oncol 2006;32:466-468.
    • (2006) Eur J Surg Oncol , vol.32 , pp. 466-468
    • Yang, J.L.1    Hannan, M.T.2    Russell, P.J.3
  • 26
    • 20244389571 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor, ERBB2 and KIT in adult soft tissue sarcomas: A clinicopathologic study of 281 cases
    • Sato O, Wada T, Kawai A, et al. Expression of epidermal growth factor receptor, ERBB2 and KIT in adult soft tissue sarcomas: a clinicopathologic study of 281 cases. Cancer 2005;103:1881-1890.
    • (2005) Cancer , vol.103 , pp. 1881-1890
    • Sato, O.1    Wada, T.2    Kawai, A.3
  • 27
    • 15744376982 scopus 로고    scopus 로고
    • Endometrial stromal sarcomas frequently express epidermal growth factor receptor (EGFR, HER-1): Potential basis for a new therapeutic approach
    • Moinfar F, Gogg-Kamerer M, Sommersacher A, et al. Endometrial stromal sarcomas frequently express epidermal growth factor receptor (EGFR, HER-1): potential basis for a new therapeutic approach. Am J Surg Pathol 2005;29:485-489.
    • (2005) Am J Surg Pathol , vol.29 , pp. 485-489
    • Moinfar, F.1    Gogg-Kamerer, M.2    Sommersacher, A.3
  • 28
    • 1542615081 scopus 로고    scopus 로고
    • Cell surface expression of epidermal growth factor receptor and Her-2 with nuclear expression of Her-4 in primary osteosarcoma
    • Hughes DP, Thomas DG, Giordano TJ, Baker LH, McDonagh KT. Cell surface expression of epidermal growth factor receptor and Her-2 with nuclear expression of Her-4 in primary osteosarcoma. Cancer Res 2004;64:2047-2053.
    • (2004) Cancer Res , vol.64 , pp. 2047-2053
    • Hughes, D.P.1    Thomas, D.G.2    Giordano, T.J.3    Baker, L.H.4    McDonagh, K.T.5
  • 29
    • 0141648453 scopus 로고    scopus 로고
    • Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology
    • Nielsen TO, Hsu FD, O'Connell JX, et al. Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. Am J Pathol 2003;163:1449-1456.
    • (2003) Am J Pathol , vol.163 , pp. 1449-1456
    • Nielsen, T.O.1    Hsu, F.D.2    O'Connell, J.X.3
  • 30
    • 0022345144 scopus 로고
    • Evidence for increased epidermal growth factor receptors in human sarcomas
    • Gusterson B, Cowley G, McIlhinney J, et al. Evidence for increased epidermal growth factor receptors in human sarcomas. Int J Cancer 1985;36:689-693.
    • (1985) Int J Cancer , vol.36 , pp. 689-693
    • Gusterson, B.1    Cowley, G.2    McIlhinney, J.3
  • 31
    • 33750332521 scopus 로고    scopus 로고
    • ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib
    • Yang Y, Ikezoe T, Nishioka C, et al. ZD6474 induces growth arrest and apoptosis of GIST-T1 cells, which is enhanced by concomitant use of sunitinib. Cancer Sci 2006;97:1404-1409.
    • (2006) Cancer Sci , vol.97 , pp. 1404-1409
    • Yang, Y.1    Ikezoe, T.2    Nishioka, C.3
  • 32
    • 22544452099 scopus 로고    scopus 로고
    • Patterns of gene amplification in gastrointestinal stromal tumors (GIST)
    • Tornillo L, Duchini G, Carafa V, et al. Patterns of gene amplification in gastrointestinal stromal tumors (GIST). Lab Invest 2005;85:921-931.
    • (2005) Lab Invest , vol.85 , pp. 921-931
    • Tornillo, L.1    Duchini, G.2    Carafa, V.3
  • 33
    • 0032781105 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood
    • Bredel M, Pollack IF, Hamilton RL, et al. Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood. Clin Cancer Res 1999;5:1786-1792.
    • (1999) Clin Cancer Res , vol.5 , pp. 1786-1792
    • Bredel, M.1    Pollack, I.F.2    Hamilton, R.L.3
  • 34
    • 10144241684 scopus 로고    scopus 로고
    • Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-alpha pathway in human astrocytic gliomas
    • Waha A, Baumann A, Wolf HK, et al. Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-alpha pathway in human astrocytic gliomas. J Neurosurg 1996;85:634-641.
    • (1996) J Neurosurg , vol.85 , pp. 634-641
    • Waha, A.1    Baumann, A.2    Wolf, H.K.3
  • 35
    • 33847349721 scopus 로고    scopus 로고
    • Epidermal growth factor receptor protein expression and gene amplification in small cell carcinoma of the urinary bladder
    • Wang X, Zhang S, MacLennan GT, et al. Epidermal growth factor receptor protein expression and gene amplification in small cell carcinoma of the urinary bladder. Clin Cancer Res 2007;13:953-957.
    • (2007) Clin Cancer Res , vol.13 , pp. 953-957
    • Wang, X.1    Zhang, S.2    MacLennan, G.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.