Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a metalloprotease inhibitor: Release of a predominant N- glycosylated 43-kDa soluble form

Journal of Biological Chemistry

Volumn 273, Issue 27, 1998, Pages 17258-17268

  Brown, Christa L ^a   Meise, Katherine S ^a   Plowman, Gregory D ^b   Coffey, Robert J ^a,b,d   Dempsey, Peter J ^a,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c SUGEN INC   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIREGULIN; BATIMASTAT; METALLOPROTEINASE INHIBITOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOTINYLATION; CELL SURFACE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS REGULATION; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CELL MEMBRANE; DOGS; ENZYME INHIBITORS; GLYCOPROTEINS; GLYCOSAMINOGLYCANS; GLYCOSYLATION; GROWTH SUBSTANCES; HUMANS; HYDROLYSIS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; METALLOENDOPEPTIDASES; MUTAGENESIS; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SOLUBILITY; TUMOR CELLS, CULTURED;

EID: 0032479422     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.27.17258     Document Type: Article

References (65)

1. Shoyab, M., McDonald, V., Bradley, J., and Todaro, G. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 6528-6532
2. Shoyab, M., Plowman, G., McDonald, V., Bradley, J., and Todaro, G. (1989) Science 243, 1074-1076
3. Plowman, G., Green, J., McDonald, V., Neubauer, M., Disteche, C., Todaro, G., and Shoyab, M. (1990) Mol. Cell. Biol. 10, 1969-1981
4. Culouscou, J., Remacle-Bonnet, M., Carlton, G., Plowman, G., and Shoyab, M. (1992) Growth Factors 7, 195-205
5. Johnson, G., Prigent, S., Gullick, W., and Stromberg, K. (1993) J. Biol. Chem. 268, 18835-18843
6. Thorne, B., and Plowman, G. (1994) Mol. Cell. Biol. 14, 1635-1646
7. Piepkorn, M., Underwood, R., Henneman. C., and Smith, L. (1995) J. Invest. Dermatol. 105, 802-809
8. Martinez-Lacaci, I., Johnson, G., Salomon, D., and Dickson, R. (1996) J. Cell. Physiol. 169, 497-508
9. Johnson, G., Saeki, T., Gordon, A., Shoyab, M., Salomon, D., and Stromberg, K. (1992) J. Cell Biol. 113, 741-751
10. Ciardiello, F., Kim, N., Saeki, T., Dono, R., Persico, M., Plowman, G., Garrigues, J., Radke, S., Todaro, G., and Salomon, D. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7792-7796
11. Cook, P., Pittelkow, M., Keeble, W., Graves-Deal, R., Coffey, R., and Shipley, G. (1992) Cancer Res. 52, 3224-3227
12. Saeki, T., Stromberg, K., Qi, C.-F., Gullick, W., Tahara, E., Normanno, N., Ciardiello, F., Kenney, N., Johnson, G., and Salomon, D. (1992) Cancer Res. 52, 3467-3473
13. Cook, P., Mattox, P., Keeble, W., Pittelkow, M., Plowman, G., Shoyab, M., Adelman, J., and Shipley, G. (1991) Mol. Cell. Biol. 11, 2547-2557
14. Li, S., Plowman, G., Buckley, S., and Shipley, G. (1992) J. Cell. Physiol. 153, 103-111
15. Piepkorn, M., Lo, C., and Plowman, G. (1994) J. Cell. Physiol. 159, 114-120
16. Normanno, N., Selvam, M., Bianco, C., Damiano, V., De Angelis, E., Grassi, M., Magliulo, G., Tortora, G., Salomon, D., and Ciardiello, F. (1995) Int. J. Cancer 62, 762-766
17. De Luca, A., Selvam, M., Sandomenico, C., Pepe, S., Bianco, A., Ciardiello, F., Salomon, D., and Normanno, N. (1997) Int. J. Cancer 73, 277-282
18. Zushi, S., Shinomura, Y., Kiyohara, T., Miyazaki, Y., Tsutsui, S., Sugimachi, M., Higashimoto, Y., Kanayama, S., and Matsuzawa, Y. (1997) Int. J. Cancer 73, 917-923
19. Kondapaka, S., Fridman, R., and Reddy, K. (1997) Int. J. Cancer 70, 722-726
20. De Boer, W., Houtsmuller, A., Izadifar, V., Muscatelli-Groux, B., Van Der Kwast, T., and Chopin, D. (1997) Int. J. Cancer 71, 284-291
21. Cook, P., Piepkorn, M., Clegg, C., Plowman, G., DeMay, J., Brown, J., and Pittlekow, M. (1997) J. Clin. Invest. 100, 2286-2294
22. Johnson, G., Kannan, B., Shoyab, M., and Stromberg, K. (1993) J. Biol. Chem. 268, 2924-2931
23. Johnson, G., Saeki, T., Auersperg, N., Gordon, A., Shoyab, M., Salomon, D., and Stromberg, K. (1991) Biochem. Biophys. Res. Commun. 180, 481-488
24. Riese, D., Kim, E., Elenius, K., Buckley, S., Klagsbrun, M., Plowman, G., and Stern, D. (1996) J. Biol. Chem. 271, 20047-20052
25. Adam, R., Drummond, D., Solic, N., Holt, S., Sharma, R., Chamberlin, S., and Davies, D. (1995) Biochim. Biophys. Acta 1266, 83-90
26. Adam, R., Chamberlin, S., and Davies, D. (1996) Growth Factors 13, 193-203
27. Thompson, S., Harris, A., Hoang, D., Ferrer, M., and Johnson, G. (1996) J. Biol. Chem. 271, 17927-17931
28. Davies, B., Brown, P., East, N., Crimmin, M., and Balkwill, F. (1993) Cancer Res. 53, 2087-2091
29. Esko, J. (1992) Adv. Exp. Med. Biol. 313, 97-106
30. Esko, J., Stewart, T., and Taylor, W. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 3197-3201
31. Dempsey, P., and Coffey, R. (1994) J. Biol. Chem. 269, 16878-16889
32. Pandiella, A., and Massague, J. (1991) J. Biol. Chem. 266, 5769-5773
33. Pandiella, A., and Massague, J. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 1726-1730
34. Bosenberg, M., Pandiella, A., and Massagué, J. (1993) J. Cell Biol. 122, 95-101
35. Raab, G., Higashiyama, S., Hetelekidis, S., Abraham, J., Damm, D., Ono, M., and Klagsbrun, M. (1994) Biochem. Biophys. Res. Commun. 204, 592-597
36. Goishi, K., Higashiyama, S., Klagsbrun, M., Nakano, N., Umata, T., Ishikawa, M., Mekada, E., and Taniguchi, N. (1995) Mol. Biol. Cell 6, 967-980
37. Lanzrein, M., Garred, O., Olsnes, S., and Sandvig, K. (1995) Biochem. J. 310, 285-289
38. Dempsey, P., Meise, K., Yoshitake, Y., Niahikawa, K., and Coffey, R. (1997) J. Cell Biol. 138, 1-12
39. Arribas, J., Coodly, L., Vollmer, P., Kishimoto, T., Rose-John, S., and Massague, J. (1996) J. Biol. Chem. 271, 11376-11382
40. Teixido, J., Wong, S., Lee, D., and Massague, J. (1990) J. Biol. Chem. 265, 6410-6415
41. Gregory, H., Thomas, C., Young, J., Willshire, I., and Garner, A. (1988) Regul. Pept. 22, 217-226
42. Dudgeon, T., Cooke, R., Baron, M., Campbell, I., Edwards, R., and Fallon, A. (1990) FEBS Lett. 261, 392-396
43. Matsunami, R., Yette, M., Stevens, A., and Niyogi, S. (1991) J. Cell. Biochem. 46, 242-249
44. Lee, D., Fenton, S., Berkowitz, E., and Hissong, M. (1995) Pharmacol. Rev. 47, 51-85
45. Huttner, W. (1988) Annu. Rev. Physiol. 50, 363-376
46. Modrell, B., McDonald, V., and Shoyab, M. (1992) Growth Factors 7, 305-314
47. Kimura, H., Fischer, W., and Schubert, D. (1990) Nature 348, 257-260
48. Kimura, H. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2165-2169
49. Higashiyama, S., Abraham, J., Miller, J., Fiddea, J., and Klagsbrun, M. (1991) Science 251, 936-939
50. Shing, Y., Christofori, G., Hanahan, D., Ono, Y., Sasada, R., Igarashi, K., and Folkman, J. (1993) Science 259, 1604-1607
51. Parries, G., Chen, K., Misono, K., and Cohen, S. (1995) J. Biol. Chem. 270, 27954-27960
52. Thompson, S., Higashiyama, S., Wood, K., Pollitt, N., Damm, D., McEnroe, G., Garrick, B., Ashton, N., Lau, K., Hancock, N., Klagsbrun, M., and Abraham, J. (1994) J. Biol. Chem. 269, 2541-2549
53. Johnson, G., and Wong, L. (1994) J. Biol. Chem. 269, 27149-27154
54. Derynck, R. (1992) Cancer Res. 58, 27-52
55. Massagué, J., and Pandiella, A. (1993) Annu. Rev. Biochem. 62, 515-541
56. Bosenberg, M., Pandiella, A., and Massague, J. (1992) Cell 71, 1157-1165
57. Ehlers, M., and Riordan, J. (1991) Biochemistry 30, 10065-10074
58. Arribas, J., and Massague, J. (1995) J. Cell Biol. 128, 433-441
59. Derynck, R., Roberts, A., Winkler, M., Chen, E., and Goeddel, D. (1984) Cell 38, 287-297
60. Bell, G., Fong, N., Stempien, M., Wormsted, M., Caput, D., Ku, L., Urdea, M., Rall, L., and Sanchez-Pescador, R. (1986) Nucleic Acids Res. 14, 8427-8446
61. Ehlers, M., Schwager, S., Scholle, R., Manji, G., Brandt, W., and Riordan, J. (1996) Biochemistry 35, 9549-9559
62. Wolfsberg, T., Primakoff, P., Myles, D., and White, J. (1995) J. Cell Biol. 131, 275-278
63. Black, R., Rauch, C., Kozlosky, C., Peschon, J., Slack, J., Wolfson, M., Castner, B., Stocking, K., Reddy, P., Srinivasan, S., Nelson, N., Boiani, N., Schooley, K., Gerhart, M., Davis, R., Fitzner, J., Johnson, R., Paxton, R., March, C., and Cerretti, D. (1997) Nature 385, 729-733
64. Moss, M., Jin, S., Milla, M., Burkhart, W., Carter, H., Chen, W., Clay, W., Didsbury, J., Hassler, D., Hoffman, C., Kost, T., Lambert, M., Leesntizer, M., McCauley, P., McGeehan, G., Mitchell, J., Moyer, M., Pahel, G., Rocque, W., Overton, L., Schoenen, F., Seaton, T., Su, J., Warner, J., Willard, D., and Becherer, J. (1997) Nature 385, 733-736
65. Inui, S., Higashiyama, S., Hashimoto, K., Higashiyama, M., Yoshikawa, K., and Taniguchi, N. (1997) J. Cell. Physiol. 171, 291-298