Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein

Experimental Neurology

Volumn 217, Issue 2, 2009, Pages 347-352

  Race, Brent ^a   Meade White, Kimberly ^a   Race, Richard ^a   Baumann, Frank ^b   Aguzzi, Adriano ^b   Chesebro, Bruce ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Astroglia; Glycophosphatidylinositol anchor; Granule cell neurons; Neurodegeneration; Prion; Truncated prion protein

Indexed keywords

PRION PROTEIN; TRUNCATED PRION PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN STEM; CELL TYPE; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; CEREBELLUM CORTEX; CONTROLLED STUDY; DISEASE ASSOCIATION; EXTRACELLULAR FLUID; FATALITY; GRANULAR CELL; MACROGLIA; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SURVIVAL TIME; TONOPLAST; WHITE MATTER; WILD TYPE;

ANIMALS; ASTROCYTES; CELL COMMUNICATION; CENTRAL NERVOUS SYSTEM; EXTRACELLULAR FLUID; FEMALE; GENE THERAPY; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR WEIGHT; NERVE DEGENERATION; NEURONS; PEPTIDE FRAGMENTS; PRION DISEASES; PRIONS;

EID: 67349266190     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.03.017     Document Type: Article

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