Profiling of the early transcriptional response of murine γδ T cells following TCR stimulation

Molecular Immunology

Volumn 46, Issue 11-12, 2009, Pages 2429-2438

  Laird, Renee M ^a   Hayes, Sandra M ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

T cells; TCR signal transduction; Transcriptional profiling

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; EFFECTOR CELL; GAMMA DELTA T LYMPHOCYTE; GENE CONTROL; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNITY; IMMUNOCOMPETENT CELL; INFECTION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ANIMALS; ANTIBODIES, MONOCLONAL; GENE EXPRESSION PROFILING; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

MURINAE; MUS;

EID: 67349254972     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.03.029     Document Type: Article

References (61)

1. Beima K.M., Miazgowicz M.M., Lewis M.D., Yan P.S., Huang T.H.-M., and Weinmann A.S. T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects. J. Biol. Chem. 281 (2006) 11992-12000
2. Boismenu R., and Havran W.L. Modulation of epithelial cell growth by intraepithelial γδ T cells. Science 266 (1994) 1252-1255
3. Boismenu R., Feng L., Xia Y.Y., Chang J.C., and Havran W.L. Chemokine expression by intraepithelial γδ T cells. Implications for the recruitment of inflammatory cells to damaged epithelia. J. Immunol. 157 (1996) 985-992
4. Boismenu R., and Havran W.L. γδ T cells in host defense and epithelial cell biology. Clin. Immunol. Immunopathol. 86 (1998) 121-133
5. Brenner M.B., McLean J., Dialynas D.P., Strominger J.L., Smith J.A., Owen F.L., Seidman J.G., Ip S., Rosen F., and Krangel M.S. Nature 322 (1986) 145-149
6. Carding S.R., and Egan P.J. γδ T cells: functional plasticity and heterogeneity. Nat. Rev. Immunol. 2 (2002) 336-345
7. Chen L., Cencioni M.T., Angelini D.F., Borsellino G., Battistini L., and Brosnan C.F. Transcriptional profiling of γδ T cells identifies a role for vitamin D in the immunoregulation of the Vγ9Vδ2 response to phosphate-containing ligands. J. Immunol. 174 (2005) 6144-6152
8. Chen L., He W., Kim S.T., Tao J., Gao Y., Chi H., Intlekofer A.M., Harvey B., Reiner S.L., Yin Z., Flavell R.A., and Craft J. Epigenetic and transcriptional programs lead to default IFN-γ production by γδ T cells. J. Immunol. 178 (2007) 2730-2736
9. Chen Y., Chou K., Fuchs E., Havran W.L., and Boismenu R. Protection of the intestinal mucosa by intraepithelial γδ T cells. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 1433-14343
10. Chien Y., Becker D.M., Lindsten T., Okamura M., Cohen D.I., and Davis M.M. A third type of murine T-cell receptor gene. Nature 312 (1984) 31-35
11. Chien Y.H., Iwashima M., Kaplan K.B., Elliot J.F., and Davis M.M. A new T-cell receptor gene located with the alpha locus and expressed early in T-cell differentiation. Nature 327 (1987) 677-682
12. Chien Y.-H., Jores R., and Crowley M.P. Recognition by γ/δ T cells. Annu. Rev. Immunol. 14 (1996) 511-532
13. + T cell responses during and after acute lymphocytic choriomeningitis virus infection. J. Immunol. 171 (2003) 3928-3935
14. Egan P., and Carding S. Downmodulation of the inflammatory response to bacterial infection by γδ T cells cytotoxic for activated macrophages. J. Exp. Med. 191 (2000) 2145-2158
15. Fahrer A.M., Konigshofer T., Kerr E.M., Ghandour G., Mack D.H., Davis M.M., and Chien Y.-H. Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 10261-10266
16. Ferrick D.A., Schrenzel M.D., Mulvania T., Hsieh B., Ferlin W.G., and Lepprt H. Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo. Nature 411 (1995) 820-824
17. Fields P.E., Kim S.T., and Flavell R.A. Cutting edge: changes in histone acetylation at the IL-4 and IFN-γ loci accompany Th1/Th2 differentiation. J. Immunol. 169 (2002) 647-650
18. Filby A., Seddon B., Kleczkowska J., Salmond R., Tomlinson P., Smida M., Lindquist J.A., Schraven B., and Zamoyska R. Fyn regulates the duration of TCR engagement need for commitment to effector function. J. Immunol. 179 (2007) 4635-4644
19. Gao Y., Yang W., Pam M., Scully E., Girardi M., Augenlicht L.H., Craft J., and Yin Z. γδ T cells provide an early source of interferon γ in tumor immunity. J. Exp. Med. 198 (2003) 433-442
20. + T cells to different stages of chemically induced skin cancer. J. Exp. Med. 198 (2003) 747-755
21. + intraepithelial lymphocytes. Nature 333 (1988) 855-858
22. Graff J.C., Behnke M., Radke J., White M., and Jutila M. A comprehensive SAGE database for the analysis of γδ T cells. Int. Immunol. 18 (2006) 613-626
23. Hayday A.C. γδ cells: a right time and a right place for a conserved third way of protection. Annu. Rev. Immunol. 18 (2000) 975-1026
24. Hayes S.M., and Love P.E. Distinct structure and signaling potential of the γδTCR complex. Immunity 16 (2002) 827-838
25. Hayes S.M., Li L.Q., and Love P.E. TCR signal strength influences αβ/γδ lineage fate. Immunity 22 (2005) 582-593
26. Hedges J.F., Cockrell D., Jackiw L., Meissner N., and Jutila M.A. Differential mRNA expression in circulating γδ T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol. 73 (2003) 306-314
27. + T cell activation. Int. Immunol. 16 (2004) 1711-1721
28. Hiromatsu K., Yoshikai Y., Matsuzaki G., Ohga S., Muramori K., Matsumoto K., Bluestone J.A., and Nomoto K. A protective role of γ/δ T cells in primary infection with Listeria monocytogenes in mice. J. Exp. Med. 175 (1992) 49-56
29. Huber S., Shi C., and Budd R.C. γδ T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand. J. Virol. 76 (2002) 6487-6494
30. Jameson J., Ugarte K., Chen N., Yachi P., Fuchs E., Boismenu R., and Havran W.L. A role for skin γδ T cells in wound repair. Science 296 (2002) 747-749
31. Kaech S.M., Hemby S., Kersh E., and Ahmed R. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111 (2002) 837-851
32. Kress E., Hedges J.F., and Jutila M.A. Distinct gene expression in human Vδ1 and Vδ2 γδ T cells following non-TCR agonist stimulation. Mol. Immunol. 43 (2006) 2002-2011
33. + γδ T cells. J. Leukoc. Biol. 80 (2006) 939-952
34. + T cells. J. Immunol. 166 (2001) 7335-7344
35. Lund R.J., Löytömäki M., Naumanen T., Dixon C., Chen Z., Ahlfors A., Tuomela S., Tahvanainen J., Scheinin J., Henttinen T., Rasool O., and Lahesmaa R. Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation. J. Immunol. 178 (2007) 3648-3660
36. + T cells. J. Immunol. 181 (2008) 5374-5385
37. Matis L.A., Cron R., and Bluestone J.A. Major histocompatibility complex linked specificity of γ/δ receptor bearing T lymphocytes. Nature 330 (1987) 263-264
38. McMahon S.B., and Monroe J.G. The role of early growth response gene 1 (egr-1) in regulation of the immune response. J. Leukoc. Biol. 60 (1996) 159-166
39. Meissner N., Radke J., Hedges J.F., White M., Behnke M., Bertolino S., Abrahamsen M., and Jutila M.A. Serial analysis of gene expression in circulating γδ T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles. J. Immunol. 170 (2003) 356-364
40. Melichar H.J., Narayan K., Der S.D., Hiraoka Y., Gardiol N., Jeannet G., Held W., Chambers C.A., and Kang J. Regulation of γδ versus αβ T lymphocyte differentiation by the transcription factor Sox13. Science 315 (2007) 230-233
41. Nikula T., West A., Katajamaa M., Lönnberg T., Sara R., Aittokallio T., Nevalainen O.S., and Lahesmaa R. A human ImmunoChip cDNA microarray provides a comprehensive tool to study immune responses. J. Immunol. Methods 303 (2005) 122-134
42. Nurieva R.I., Chung Y., Hwang D., Yang X.O., Kang H.S., Ma L., Wang Y.-H., Watowich S.S., Jetten A.M., Tian Q., and Dong C. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineage. Immunity 29 (2008) 138-149
43. Pao W., Wen L., Smith A.L., Gulbranson-Judge A., Zheng B., Kelsoe G., MacLennon I.C., Owen M.J., and Hayday A.C. γδ T cell help of B cells induced by repeated parasitic infection, in the absence of other T cells. Curr. Biol. 6 (1996) 1317-1325
44. + thymocytes. Immunity 7 (1997) 243-254
45. + cells. Nat. Immunol. 4 (2003) 991-998
46. Raulet D.H. The structure, function, and molecular genetics of the γ/δ T cell receptor. Annu. Rev. Immunol. 7 (1989) 175-207
47. Roark C.L., Simonian P.L., Fontenot A.P., Born W.K., and O'Brien R.L. γδ T cells: an important source of IL-17. Curr. Opin. Immunol. 20 (2008) 353-357
48. Rogge L., Bianchi E., Biffi M., Bono E., Chang S.Y., Alexander H., Santini C., Ferrari G., Sinigaglia L., Seiler M., Neeb M., Mous J., Sinigaglia F., and Certa U. Transcript imaging of the development of human T helper cells using oligonucleotide arrays. Nat. Genet. 25 (2000) 96-101
49. Sharp L.L., Jameson J.M., Cauvi G., and Havran W.L. Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1. Nat. Immunol. 6 (2005) 73-79
50. + intraepithelial lymphocytes provided by serial analysis of gene expression (SAGE). Immunity 15 (2001) 419-434
51. Silva-Santos B., Pennington D.J., and Hayday A.C. Lymphotoxin-mediated regulation of γδ cell differentiation by αβ T cell progenitors. Science 307 (2005) 925-928
52. Sim G.K., Olsson C., and Augustin A. Commitment and maintenance of the αβand γδ T cell lineages. J. Immunol. 154 (1995) 5821-5831
53. Skerka C., Decker E.L., and Zipfel P.F. A regulatory element in the human interluekin 2 gene promoter is a binding site for the zinc finger proteins Sp1 and EGR-1. J. Biol. Chem. 270 (1995) 22500-22506
54. Stein P.L., Lee H.M., Rich S., and Soriano P. pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70 (1992) 741-750
55. Sugie K., Jeon M.S., and Grey H.M. Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 14859-14864
56. Taghon T., Yui M.A., Pant R., Diamond R.A., and Rothenberg E.V. Developmental and molecular characterization of emerging β- and γδ-selected pre-T cells in the adult mouse thymus. Immunity 24 (2006) 53-64
57. high γδ T cells in Lyme arthritis. J. Exp. Med. 184 (1996) 2109-2117
58. Wen L., Pao W., Wong F.S., Peng Q., Craft J., et al. Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non αβ" T cells. J. Exp. Med. 183 (1996) 2271-2282
59. Wen L., Barber D.F., Pao W., Wong F.S., Owen M.J., and Hayday A. Primary γδ cell clones can be defined phenotypically and functionally as Th1/Th2 cells and illustrate the association of CD4 with Th2 differentiation. J. Immunol. 160 (1998) 1965-1974
60. Xi H., and Kersh G.J. Induction of the early growth response gene 1 promoter by TCR agonists and partial agonists: ligand potency is related to sustained phosphorylation of extracellular signal-related kinase substrates. J. Immunol. 170 (2003) 315-324
61. Yin Z., Chen C.H., Szabo S.J., Glimcher L.H., Ray A., and Craft J. T-bet expression and failure of GATA-3 cross-regulation lead to default production of IFN-γ by γδ T cell. J. Immunol. 168 (2002) 1566-1571