메뉴 건너뛰기




Volumn 9, Issue 3, 2009, Pages 194-201

Influence of the G2677T/C3435T haplotype of MDR1 on P-glycoprotein trafficking and ibutilide-induced block of HERG

Author keywords

[No Author keywords available]

Indexed keywords

FEXOFENADINE; GLYCOPROTEIN P; IBUTILIDE; MULTIDRUG RESISTANCE PROTEIN 1; POTASSIUM CHANNEL HERG;

EID: 67349225471     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2009.1     Document Type: Article
Times cited : (13)

References (44)
  • 1
    • 1442306232 scopus 로고    scopus 로고
    • Drug-induced prolongation of the QT interval
    • Roden DM. Drug-induced prolongation of the QT interval. N Engl J Med 2004; 350: 1013-1022.
    • (2004) N Engl J Med , vol.350 , pp. 1013-1022
    • Roden, D.M.1
  • 2
    • 0242511818 scopus 로고    scopus 로고
    • Genetic polymorphisms, drugs, and proarrhythmia
    • Roden DM. Genetic polymorphisms, drugs, and proarrhythmia. J Intervent Cardiac Electrophysiol 2003; 9: 131-135.
    • (2003) J Intervent Cardiac Electrophysiol , vol.9 , pp. 131-135
    • Roden, D.M.1
  • 4
    • 0034244378 scopus 로고    scopus 로고
    • Haverkamp W, Breithardt G, Camm AJ, Janse MJ, Rosen MR, Antzelevitch C et al. The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: Clinical and regulatory implications. Report on a Policy Conference of the European Society of Cardiology. Eur Heart J 2000; 21: 1216-1231.
    • Haverkamp W, Breithardt G, Camm AJ, Janse MJ, Rosen MR, Antzelevitch C et al. The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: Clinical and regulatory implications. Report on a Policy Conference of the European Society of Cardiology. Eur Heart J 2000; 21: 1216-1231.
  • 6
    • 0029976743 scopus 로고    scopus 로고
    • Molecular analysis of a binding site for quinidine in a human cardiac delayed rectifier K+ channel: Role of S6 in antiarrhythmic drug binding
    • Yeola SW, Rich TC, Uebele VN, Tamkun MM, Snyders DJ. Molecular analysis of a binding site for quinidine in a human cardiac delayed rectifier K+ channel: Role of S6 in antiarrhythmic drug binding. Circ Res 1996; 78: 1105-1114.
    • (1996) Circ Res , vol.78 , pp. 1105-1114
    • Yeola, S.W.1    Rich, T.C.2    Uebele, V.N.3    Tamkun, M.M.4    Snyders, D.J.5
  • 7
    • 0037161355 scopus 로고    scopus 로고
    • Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
    • Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC et al. Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation 2002; 105: 1943-1948.
    • (2002) Circulation , vol.105 , pp. 1943-1948
    • Yang, P.1    Kanki, H.2    Drolet, B.3    Yang, T.4    Wei, J.5    Viswanathan, P.C.6
  • 10
    • 0027515633 scopus 로고
    • Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs
    • Makkar RR, Fromm BS, Steinman RT, Meissner MD, Lehmann MH. Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. JAMA 1993; 270: 2590-2597.
    • (1993) JAMA , vol.270 , pp. 2590-2597
    • Makkar, R.R.1    Fromm, B.S.2    Steinman, R.T.3    Meissner, M.D.4    Lehmann, M.H.5
  • 11
    • 7144264410 scopus 로고    scopus 로고
    • Electrocardiographic and clinical predictors of torsades de pointes induced by almolanat infusion in patients with chronic atrial fibrillation or flutter: A prospective study
    • Houltz B, Darpo B, Edvardsson N, Blomstrom P, Brachmann J, Crijns HJ et al. Electrocardiographic and clinical predictors of torsades de pointes induced by almolanat infusion in patients with chronic atrial fibrillation or flutter: A prospective study. PACE 1998; 21: 1044-1057.
    • (1998) PACE , vol.21 , pp. 1044-1057
    • Houltz, B.1    Darpo, B.2    Edvardsson, N.3    Blomstrom, P.4    Brachmann, J.5    Crijns, H.J.6
  • 12
    • 0037065916 scopus 로고    scopus 로고
    • Calmodulin inhibitor W-7 unmasks a novel electrocardiographic parameter that predicts initiation of torsade de pointes
    • Gbadebo TD, Trimble RW, Khoo MSC, Temple J, Roden DM, Anderson ME. Calmodulin inhibitor W-7 unmasks a novel electrocardiographic parameter that predicts initiation of torsade de pointes. Circulation 2002; 105: 770-774.
    • (2002) Circulation , vol.105 , pp. 770-774
    • Gbadebo, T.D.1    Trimble, R.W.2    Khoo, M.S.C.3    Temple, J.4    Roden, D.M.5    Anderson, M.E.6
  • 13
    • 0034163543 scopus 로고    scopus 로고
    • Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome
    • Shimizu W, Antzelevitch C. Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome. J Amer College Cardiol 2000; 35: 778-786.
    • (2000) J Amer College Cardiol , vol.35 , pp. 778-786
    • Shimizu, W.1    Antzelevitch, C.2
  • 14
    • 0035822048 scopus 로고    scopus 로고
    • Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
    • Zhou M, Morais-Cabral JH, Mann S, MacKinnon R. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature 2001; 411: 657-661.
    • (2001) Nature , vol.411 , pp. 657-661
    • Zhou, M.1    Morais-Cabral, J.H.2    Mann, S.3    MacKinnon, R.4
  • 15
    • 0034952901 scopus 로고    scopus 로고
    • The influence of CYP2D6 polymorphism on the antiarrhythmic efficacy of propafenone in patients with paroxysmal atrial fibrillation during 3 months propafenone prophylactic treatment
    • Jazwinska-Tarnawska E, Orzechowska-Juzwenko K, Niewinski P, Rzemislawska Z, Loboz-Grudzien K, Dmochowska-Perz M et al. The influence of CYP2D6 polymorphism on the antiarrhythmic efficacy of propafenone in patients with paroxysmal atrial fibrillation during 3 months propafenone prophylactic treatment. Int J Clin Pharmacol Ther 2001; 39: 288-292.
    • (2001) Int J Clin Pharmacol Ther , vol.39 , pp. 288-292
    • Jazwinska-Tarnawska, E.1    Orzechowska-Juzwenko, K.2    Niewinski, P.3    Rzemislawska, Z.4    Loboz-Grudzien, K.5    Dmochowska-Perz, M.6
  • 16
    • 4243098329 scopus 로고    scopus 로고
    • Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein
    • Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJY. Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein. J Pharmacol Exp Ther 2004; 310: 1199-1207.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 1199-1207
    • Woodahl, E.L.1    Yang, Z.2    Bui, T.3    Shen, D.D.4    Ho, R.J.Y.5
  • 17
    • 0029892497 scopus 로고    scopus 로고
    • P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
    • Schinkel AH, Wagenaar E, Mol CAAM, van Deemter L. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 1996; 97 2517-2524.
    • (1996) J Clin Invest , vol.97 , pp. 2517-2524
    • Schinkel, A.H.1    Wagenaar, E.2    Mol, C.A.A.M.3    van Deemter, L.4
  • 18
    • 23444460865 scopus 로고    scopus 로고
    • Placental transfer of antiretroviral drugs
    • Marzolini C, Kim RB. Placental transfer of antiretroviral drugs. Clin Pharmacol Ther 2005; 78: 118-122.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 118-122
    • Marzolini, C.1    Kim, R.B.2
  • 19
    • 0346728729 scopus 로고    scopus 로고
    • The ABCs of drug transport in intestine and liver: Efflux proteins limiting drug absorption and bioavailability
    • Chan LMS, Lowes S, Hirst BH. The ABCs of drug transport in intestine and liver: Efflux proteins limiting drug absorption and bioavailability. Eur J Pharm Sci 2004; 21: 25-51.
    • (2004) Eur J Pharm Sci , vol.21 , pp. 25-51
    • Chan, L.M.S.1    Lowes, S.2    Hirst, B.H.3
  • 20
    • 20444466590 scopus 로고    scopus 로고
    • Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics
    • Niemi M, Backman JT, Kajosaari LI, Leathart JB, Neuvonen M, Daly AK et al. Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics. Clin Pharmacol Ther 2005; 77: 468-478.
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 468-478
    • Niemi, M.1    Backman, J.T.2    Kajosaari, L.I.3    Leathart, J.B.4    Neuvonen, M.5    Daly, A.K.6
  • 21
    • 12344262373 scopus 로고    scopus 로고
    • Blood-brain barrier active efflux transporters: ATP-binding cassette gene family
    • Potschka H, Loscher W. Blood-brain barrier active efflux transporters: ATP-binding cassette gene family. NeuroRx 2005; 2: 86-98.
    • (2005) NeuroRx , vol.2 , pp. 86-98
    • Potschka, H.1    Loscher, W.2
  • 22
    • 12344261030 scopus 로고    scopus 로고
    • Kusuhara H, Sugiyama Y. Active efflux across the blood brain barrier: role of the solute carrier family. NeuroRx 22005; 2: 73-85.
    • Kusuhara H, Sugiyama Y. Active efflux across the blood brain barrier: role of the solute carrier family. NeuroRx 22005; 2: 73-85.
  • 23
    • 24344439264 scopus 로고    scopus 로고
    • Transporters and drug therapy: Implications for drug disposition and disease
    • Ho RH, Kim RB. Transporters and drug therapy: Implications for drug disposition and disease. Clin Pharmacol Ther 2005; 78: 260-277.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 260-277
    • Ho, R.H.1    Kim, R.B.2
  • 24
    • 33645310407 scopus 로고    scopus 로고
    • Uptake of cardiovascular drugs into the human heart: Expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5)
    • Grube M, Meyer zu Schwabedissen HEU, Prager D, Haney J, Moritz KU, Meissner K et al. Uptake of cardiovascular drugs into the human heart: Expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5). Circulation 2006; 113: 1114-1122.
    • (2006) Circulation , vol.113 , pp. 1114-1122
    • Grube, M.1    Meyer zu Schwabedissen, H.E.U.2    Prager, D.3    Haney, J.4    Moritz, K.U.5    Meissner, K.6
  • 25
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70 189-199.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 189-199
    • Kim, R.B.1    Leake, B.F.2    Choo, E.F.3    Dresser, G.K.4    Kubba, S.V.5    Schwarz, U.I.6
  • 26
    • 0036693051 scopus 로고    scopus 로고
    • Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein
    • Kurata Y, Ieiri I, Kimura M, Morita T, Irie S, Urae A et al. Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein. Clin Pharmacol Ther 2002; 72: 209-219.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 209-219
    • Kurata, Y.1    Ieiri, I.2    Kimura, M.3    Morita, T.4    Irie, S.5    Urae, A.6
  • 27
    • 33845401618 scopus 로고    scopus 로고
    • Effect of ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine in healthy subjects
    • Kim KA, Park PW, Park JY. Effect of ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine in healthy subjects. Brit J Clin Pharmacol 2007; 63: 53-58.
    • (2007) Brit J Clin Pharmacol , vol.63 , pp. 53-58
    • Kim, K.A.1    Park, P.W.2    Park, J.Y.3
  • 28
    • 0036731995 scopus 로고    scopus 로고
    • MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
    • Illmer T, Schuler US, Thiede C, Schwarz UI, Kim RB, Gotthard S et al MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 2002; 62: 4955-4962.
    • (2002) Cancer Res , vol.62 , pp. 4955-4962
    • Illmer, T.1    Schuler, U.S.2    Thiede, C.3    Schwarz, U.I.4    Kim, R.B.5    Gotthard, S.6
  • 29
    • 0037183584 scopus 로고    scopus 로고
    • Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene, 8-27-2002
    • Yamauchi A, Ieiri I, Kataoka Y, Tanabe M, Nishizaki T, Oishi R et al Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene. Transplantation 2002; 74: 571-572. 8-27-2002.
    • (2002) Transplantation , vol.74 , pp. 571-572
    • Yamauchi, A.1    Ieiri, I.2    Kataoka, Y.3    Tanabe, M.4    Nishizaki, T.5    Oishi, R.6
  • 30
    • 34648857526 scopus 로고    scopus 로고
    • 1199G4A and 2677G4T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation, 10-17-2007
    • Elens L, Capron A, Kerckhove VV, Lerut J, Mourad M, Lison D et al. 1199G4A and 2677G4T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation. Pharmacogenet Pharmacogenomics 2007; 17: 873-883. 10-17-2007.
    • (2007) Pharmacogenet Pharmacogenomics , vol.17 , pp. 873-883
    • Elens, L.1    Capron, A.2    Kerckhove, V.V.3    Lerut, J.4    Mourad, M.5    Lison, D.6
  • 32
    • 0037129911 scopus 로고    scopus 로고
    • Pharmacological rescue of human K+ channel long-QT2 mutations
    • Rajamani S, Anderson CL, Anson BD, January CT. Pharmacological rescue of human K+ channel long-QT2 mutations. Circulation 2002; 105: 2830-2835.
    • (2002) Circulation , vol.105 , pp. 2830-2835
    • Rajamani, S.1    Anderson, C.L.2    Anson, B.D.3    January, C.T.4
  • 33
    • 35848960546 scopus 로고    scopus 로고
    • Associations between MDR1 gene polymorphisms and schizophrenia and therapeutic response to olanzapine in female schizophrenic patients
    • Bozina N, Kuzman MR, Medved V, Jovanovic N, Sertic J, Hotujac L. Associations between MDR1 gene polymorphisms and schizophrenia and therapeutic response to olanzapine in female schizophrenic patients. J Psychiatr Res 2008; 42: 89-97.
    • (2008) J Psychiatr Res , vol.42 , pp. 89-97
    • Bozina, N.1    Kuzman, M.R.2    Medved, V.3    Jovanovic, N.4    Sertic, J.5    Hotujac, L.6
  • 35
    • 33645854040 scopus 로고    scopus 로고
    • MDR1 polymorphisms predict the response to etoposide-cisplatin combination chemotherapy in small cell lung cancer
    • Sohn JW, Lee SY, Lee SJ, Kim EJ, Cha SI, Kim CH et al. MDR1 polymorphisms predict the response to etoposide-cisplatin combination chemotherapy in small cell lung cancer. Jpn J Clin Oncol 2006; 36: 137-141.
    • (2006) Jpn J Clin Oncol , vol.36 , pp. 137-141
    • Sohn, J.W.1    Lee, S.Y.2    Lee, S.J.3    Kim, E.J.4    Cha, S.I.5    Kim, C.H.6
  • 36
    • 33645691608 scopus 로고    scopus 로고
    • Multidrug resistance-1 gene polymorphisms associated with treatment outcomes in de novo acute myeloid leukemia
    • Kim DH, Park JY, Sohn SK, Lee NY, Baek JH, Jeon SB et al. Multidrug resistance-1 gene polymorphisms associated with treatment outcomes in de novo acute myeloid leukemia. Int J Cancer 2006; 118: 2195-2201.
    • (2006) Int J Cancer , vol.118 , pp. 2195-2201
    • Kim, D.H.1    Park, J.Y.2    Sohn, S.K.3    Lee, N.Y.4    Baek, J.H.5    Jeon, S.B.6
  • 37
    • 33745155394 scopus 로고    scopus 로고
    • ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients
    • Seo T, Ishitsu T, Ueda N, Nakada N, Yurube K, Ueda K et al. ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients. Pharmacogenomics 2006; 7: 551-561.
    • (2006) Pharmacogenomics , vol.7 , pp. 551-561
    • Seo, T.1    Ishitsu, T.2    Ueda, N.3    Nakada, N.4    Yurube, K.5    Ueda, K.6
  • 38
    • 22944434897 scopus 로고    scopus 로고
    • Quantitative in vivo microdialysis study on the influence of multidrug transporters on the blood-brain barrier passage of oxcarbazepine: Concomitant use of hippocampal monoamines as pharmacodynamic markers for the anticonvulsant activity
    • Clinckers R, Smolders I, Meurs A, Ebinger G, Michotte Y. Quantitative in vivo microdialysis study on the influence of multidrug transporters on the blood-brain barrier passage of oxcarbazepine: concomitant use of hippocampal monoamines as pharmacodynamic markers for the anticonvulsant activity. J Pharmacol Exp Ther 2005; 314: 725-731.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 725-731
    • Clinckers, R.1    Smolders, I.2    Meurs, A.3    Ebinger, G.4    Michotte, Y.5
  • 40
    • 1642539998 scopus 로고    scopus 로고
    • Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure
    • Cha TJ, Ehrlich JR, Zhang L, Shi YF, Tardif JC, Leung TK et al. Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure. Circulation 2004; 109: 412-418.
    • (2004) Circulation , vol.109 , pp. 412-418
    • Cha, T.J.1    Ehrlich, J.R.2    Zhang, L.3    Shi, Y.F.4    Tardif, J.C.5    Leung, T.K.6
  • 41
    • 0034612363 scopus 로고    scopus 로고
    • Effects of experimental heart failure on atrial cellular and ionic electrophysiology
    • Li D, Melnyk P, Feng J, Wang Z, Petrecca K, Shrier A et al. Effects of experimental heart failure on atrial cellular and ionic electrophysiology. Circulation 2000; 101: 2631-2638.
    • (2000) Circulation , vol.101 , pp. 2631-2638
    • Li, D.1    Melnyk, P.2    Feng, J.3    Wang, Z.4    Petrecca, K.5    Shrier, A.6
  • 43
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • 8-1-1981
    • Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Archive: Eur J Physiol 1981; 391: 85-100. 8-1-1981.
    • (1981) Pflugers Archive: Eur J Physiol , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 44
    • 0034774943 scopus 로고    scopus 로고
    • Drug block of IKr: Model systems and relevance to human arrhythmias
    • Yang T, Snyders D, Roden DM. Drug block of IKr: Model systems and relevance to human arrhythmias. J Cardiovasc Pharmacol 2001; 38 737-744.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 737-744
    • Yang, T.1    Snyders, D.2    Roden, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.