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Volumn 77, Issue 6, 2005, Pages 468-478

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C8; CYTOCHROME P450 3A5; ORGANIC ANION TRANSPORTER; POLYPEPTIDE; REPAGLINIDE;

EID: 20444466590     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clpt.2005.01.018     Document Type: Article
Times cited : (334)

References (39)
  • 1
    • 0036075924 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of repaglinide
    • V. Hatorp Clinical pharmacokinetics and pharmacodynamics of repaglinide Clin Pharmacokinet 41 2002 471 483
    • (2002) Clin Pharmacokinet , vol.41 , pp. 471-483
    • Hatorp, V.1
  • 2
    • 0031593457 scopus 로고    scopus 로고
    • Bioavailability of repaglinide, a novel antidiabetic agent, administered orally in tablet or solution form or intravenously in healthy male volunteers
    • V. Hatorp, S. Oliver, C.A. Su Bioavailability of repaglinide, a novel antidiabetic agent, administered orally in tablet or solution form or intravenously in healthy male volunteers Int J Clin Pharmacol Ther 36 1998 636 641
    • (1998) Int J Clin Pharmacol Ther , vol.36 , pp. 636-641
    • Hatorp, V.1    Oliver, S.2    Su, C.A.3
  • 4
    • 0042318871 scopus 로고    scopus 로고
    • CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide
    • T.B. Bidstrup, I. Bjørnsdottir, U.G. Sidelmann, M.S. Thomsen, K.T. Hansen CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide Br J Clin Pharmacol 56 2003 305 314
    • (2003) Br J Clin Pharmacol , vol.56 , pp. 305-314
    • Bidstrup, T.B.1    Bjørnsdottir, I.2    Sidelmann, U.G.3    Thomsen, M.S.4    Hansen, K.T.5
  • 6
    • 0034912196 scopus 로고    scopus 로고
    • The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide
    • M. Niemi, P.J. Neuvonen, K.T. Kivistö The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide Clin Pharmacol Ther 70 2001 58 65
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 58-65
    • Niemi, M.1    Neuvonen, P.J.2    Kivistö, K.T.3
  • 7
    • 0037627707 scopus 로고    scopus 로고
    • Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: Potentially hazardous interaction between gemfibrozil and repaglinide
    • M. Niemi, J.T. Backman, M. Neuvonen, P.J. Neuvonen Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide potentially hazardous interaction between gemfibrozil and repaglinide Diabetologia 46 2003 347 351
    • (2003) Diabetologia , vol.46 , pp. 347-351
    • Niemi, M.1    Backman, J.T.2    Neuvonen, M.3    Neuvonen, P.J.4
  • 8
    • 0028357256 scopus 로고
    • Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole
    • K.T. Olkkola, J.T. Backman, P.J. Neuvonen Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole Clin Pharmacol Ther 55 1994 481 485
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 481-485
    • Olkkola, K.T.1    Backman, J.T.2    Neuvonen, P.J.3
  • 11
    • 0031845356 scopus 로고    scopus 로고
    • Effect of clarithromycin on renal excretion of digoxin: Interaction with P-glycoprotein
    • H. Wakasugi, I. Yano, T. Ito, T. Hashida, T. Futami, R. Nohara Effect of clarithromycin on renal excretion of digoxin interaction with P-glycoprotein Clin Pharmacol Ther 64 1998 123 128
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 123-128
    • Wakasugi, H.1    Yano, I.2    Ito, T.3    Hashida, T.4    Futami, T.5    Nohara, R.6
  • 12
    • 3242785620 scopus 로고    scopus 로고
    • Importance of P-glycoprotein at blood-tissue barriers
    • M.F. Fromm Importance of P-glycoprotein at blood-tissue barriers Trends Pharmacol Sci 25 2004 423 429
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 423-429
    • Fromm, M.F.1
  • 13
    • 1942487810 scopus 로고    scopus 로고
    • The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjects
    • M. Niemi, L.I. Kajosaari, M. Neuvonen, J.T. Backman, P.J. Neuvonen The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjects Br J Clin Pharmacol 57 2004 441 447
    • (2004) Br J Clin Pharmacol , vol.57 , pp. 441-447
    • Niemi, M.1    Kajosaari, L.I.2    Neuvonen, M.3    Backman, J.T.4    Neuvonen, P.J.5
  • 14
    • 0036892714 scopus 로고    scopus 로고
    • Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes
    • J.S. Wang, M. Neuvonen, X. Wen, J.T. Backman, P.J. Neuvonen Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes Drug Metab Dispos 30 2002 1352 1356
    • (2002) Drug Metab Dispos , vol.30 , pp. 1352-1356
    • Wang, J.S.1    Neuvonen, M.2    Wen, X.3    Backman, J.T.4    Neuvonen, P.J.5
  • 15
    • 4644301418 scopus 로고    scopus 로고
    • Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: Analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil
    • Y. Shitara, M. Hirano, H. Sato, Y. Sugiyama Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil J Pharmacol Exp Ther 311 2004 228 236
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 228-236
    • Shitara, Y.1    Hirano, M.2    Sato, H.3    Sugiyama, Y.4
  • 16
    • 1242272736 scopus 로고    scopus 로고
    • Organic anion transporting polypeptides of the OATP/SLC21 family: Phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties
    • B. Hagenbuch, P.J. Meier Organic anion transporting polypeptides of the OATP/SLC21 family phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties Pflugers Arch 447 2004 653 665
    • (2004) Pflugers Arch , vol.447 , pp. 653-665
    • Hagenbuch, B.1    Meier, P.J.2
  • 17
    • 0037328994 scopus 로고    scopus 로고
    • Pharmacogenetics of the major polymorphic metabolizing enzymes
    • A.K. Daly Pharmacogenetics of the major polymorphic metabolizing enzymes Fundam Clin Pharmacol 17 2003 27 41
    • (2003) Fundam Clin Pharmacol , vol.17 , pp. 27-41
    • Daly, A.K.1
  • 19
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • P. Kuehl, J. Zhang, Y. Lin, J. Lamba, M. Assem, J. Schuetz Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression Nat Genet 27 2001 383 391
    • (2001) Nat Genet , vol.27 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3    Lamba, J.4    Assem, M.5    Schuetz, J.6
  • 21
    • 1642523162 scopus 로고    scopus 로고
    • Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
    • C. Marzolini, E. Paus, T. Buclin, R.B. Kim Polymorphisms in human MDR1 (P-glycoprotein) recent advances and clinical relevance Clin Pharmacol Ther 75 2004 13 33
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 13-33
    • Marzolini, C.1    Paus, E.2    Buclin, T.3    Kim, R.B.4
  • 23
    • 0035929574 scopus 로고    scopus 로고
    • Polymorphisms in OATP-C: Identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
    • R.G. Tirona, B.F. Leake, G. Merino, R.B. Kim Polymorphisms in OATP-C identification of multiple allelic variants associated with altered transport activity among European- and African-Americans J Biol Chem 276 2001 35669 35675
    • (2001) J Biol Chem , vol.276 , pp. 35669-35675
    • Tirona, R.G.1    Leake, B.F.2    Merino, G.3    Kim, R.B.4
  • 24
    • 0038209381 scopus 로고    scopus 로고
    • Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics
    • Y. Nishizato, I. Ieiri, H. Suzuki, M. Kimura, K. Kawabata, T. Hirota Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes consequences for pravastatin pharmacokinetics Clin Pharmacol Ther 73 2003 554 565
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 554-565
    • Nishizato, Y.1    Ieiri, I.2    Suzuki, H.3    Kimura, M.4    Kawabata, K.5    Hirota, T.6
  • 25
    • 2042469487 scopus 로고    scopus 로고
    • Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics
    • J. Mwinyi, A. Johne, S. Bauer, I. Roots, T. Gerloff Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics Clin Pharmacol Ther 75 2004 415 421
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 415-421
    • Mwinyi, J.1    Johne, A.2    Bauer, S.3    Roots, I.4    Gerloff, T.5
  • 26
    • 3242808852 scopus 로고    scopus 로고
    • High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)
    • M. Niemi, E. Schaeffeler, T. Lang, M.F. Fromm, M. Neuvonen, C. Kyrklund High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1) Pharmacogenetics 14 2004 429 440
    • (2004) Pharmacogenetics , vol.14 , pp. 429-440
    • Niemi, M.1    Schaeffeler, E.2    Lang, T.3    Fromm, M.F.4    Neuvonen, M.5    Kyrklund, C.6
  • 27
    • 4744349916 scopus 로고    scopus 로고
    • Lack of effect of bezafibrate and fenofibrate on the pharmacokinetics and pharmacodynamics of repaglinide
    • L.I. Kajosaari, J.T. Backman, M. Neuvonen, J. Laitila, P.J. Neuvonen Lack of effect of bezafibrate and fenofibrate on the pharmacokinetics and pharmacodynamics of repaglinide Br J Clin Pharmacol 58 2004 390 396
    • (2004) Br J Clin Pharmacol , vol.58 , pp. 390-396
    • Kajosaari, L.I.1    Backman, J.T.2    Neuvonen, M.3    Laitila, J.4    Neuvonen, P.J.5
  • 28
    • 18644367631 scopus 로고    scopus 로고
    • Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease
    • T. Furuno, M.T. Landi, M. Ceroni, N. Caporaso, I. Bernucci, G. Nappi Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease Pharmacogenetics 12 2002 529 534
    • (2002) Pharmacogenetics , vol.12 , pp. 529-534
    • Furuno, T.1    Landi, M.T.2    Ceroni, M.3    Caporaso, N.4    Bernucci, I.5    Nappi, G.6
  • 29
    • 0036881149 scopus 로고    scopus 로고
    • Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
    • A. Johne, K. Kopke, T. Gerloff, I. Mai, S. Rietbrock, C. Meisel Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene Clin Pharmacol Ther 72 2002 584 594
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 584-594
    • Johne, A.1    Kopke, K.2    Gerloff, T.3    Mai, I.4    Rietbrock, S.5    Meisel, C.6
  • 30
    • 0037310871 scopus 로고    scopus 로고
    • Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin a
    • Y. Shitara, T. Itoh, H. Sato, A.P. Li, Y. Sugiyama Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A J Pharmacol Exp Ther 304 2003 610 616
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 610-616
    • Shitara, Y.1    Itoh, T.2    Sato, H.3    Li, A.P.4    Sugiyama, Y.5
  • 31
    • 1642523136 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression
    • M. Hedman, P.J. Neuvonen, M. Neuvonen, C. Holmberg, M. Antikainen Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression Clin Pharmacol Ther 75 2004 101 109
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 101-109
    • Hedman, M.1    Neuvonen, P.J.2    Neuvonen, M.3    Holmberg, C.4    Antikainen, M.5
  • 32
    • 0034495168 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of pravastatin: Mechanisms of pharmacokinetic events
    • T. Hatanaka Clinical pharmacokinetics of pravastatin mechanisms of pharmacokinetic events Clin Pharmacokinet 39 2000 397 412
    • (2000) Clin Pharmacokinet , vol.39 , pp. 397-412
    • Hatanaka, T.1
  • 33
    • 3542992126 scopus 로고    scopus 로고
    • Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine
    • S.G. Simonson, A. Raza, P.D. Martin, P.D. Mitchell, J.A. Jarcho, C.D. Brown Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine Clin Pharmacol Ther 76 2004 167 177
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 167-177
    • Simonson, S.G.1    Raza, A.2    Martin, P.D.3    Mitchell, P.D.4    Jarcho, J.A.5    Brown, C.D.6
  • 34
    • 0034791777 scopus 로고    scopus 로고
    • Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
    • D. Dai, D.C. Zeldin, J.A. Blaisdell, B. Chanas, S.J. Coulter, B.I. Ghanayem Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid Pharmacogenetics 11 2001 597 607
    • (2001) Pharmacogenetics , vol.11 , pp. 597-607
    • Dai, D.1    Zeldin, D.C.2    Blaisdell, J.A.3    Chanas, B.4    Coulter, S.J.5    Ghanayem, B.I.6
  • 35
    • 0035214173 scopus 로고    scopus 로고
    • Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism
    • A. Soyama, Y. Saito, N. Hanioka, N. Murayama, O. Nakajima, N. Katori Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism Biol Pharm Bull 24 2001 1427 1430
    • (2001) Biol Pharm Bull , vol.24 , pp. 1427-1430
    • Soyama, A.1    Saito, Y.2    Hanioka, N.3    Murayama, N.4    Nakajima, O.5    Katori, N.6
  • 36
    • 0036889666 scopus 로고    scopus 로고
    • CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes
    • N. Bahadur, J.B. Leathart, E. Mutch, D. Steimel-Crespi, S.A. Dunn, R. Gilissen CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes Biochem Pharmacol 64 2002 1579 1589
    • (2002) Biochem Pharmacol , vol.64 , pp. 1579-1589
    • Bahadur, N.1    Leathart, J.B.2    Mutch, E.3    Steimel-Crespi, D.4    Dunn, S.A.5    Gilissen, R.6
  • 37
    • 3543012028 scopus 로고    scopus 로고
    • Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms
    • E. Garcia-Martin, C. Martinez, B. Tabares, J. Frias, J.A. Agundez Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms Clin Pharmacol Ther 76 2004 119 127
    • (2004) Clin Pharmacol Ther , vol.76 , pp. 119-127
    • Garcia-Martin, E.1    Martinez, C.2    Tabares, B.3    Frias, J.4    Agundez, J.A.5
  • 39
    • 1942421704 scopus 로고    scopus 로고
    • Genomic evidence for recent positive selection at the human MDR1 gene locus
    • K. Tang, L.P. Wong, E.J. Lee, S.S. Chong, C.G. Lee Genomic evidence for recent positive selection at the human MDR1 gene locus Hum Mol Genet 13 2004 783 797
    • (2004) Hum Mol Genet , vol.13 , pp. 783-797
    • Tang, K.1    Wong, L.P.2    Lee, E.J.3    Chong, S.S.4    Lee, C.G.5


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