A cellular model for screening neuronal nitric oxide synthase inhibitors

Analytical Biochemistry

Volumn 390, Issue 1, 2009, Pages 74-78

  Fang, Jianguo ^a   Silverman, Richard B ^a  

^a Center for Molecular Innovation and Drug Discovery   (United States)

Author keywords

Cell based assay; Griess reagent; HEK 293T cells; Nitric oxide; Nitric oxide synthase inhibitor

Indexed keywords

BIOCHEMISTRY; CELLS; CYTOLOGY; DIAGNOSIS; DRUG PRODUCTS; ENZYMES; PHYSIOLOGICAL MODELS; REAGENTS;

CELL-BASED ASSAYS; GRIESS REAGENTS; HIGH THROUGHPUT SCREENING; IN-VITRO ASSAYS; NITRIC OXIDE SYNTHASE INHIBITORS; NITRIC-OXIDE SYNTHASE; POTENT COMPOUNDS; RECOMBINANT ENZYMES;

NITRIC OXIDE;

AR R17477; CALCIUM ION; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; N(G) NITROARGININE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SCREENING; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

RATTUS;

EID: 67349203863     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.04.004     Document Type: Article

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