Substituted 6-phenyl-pyridin-2-ylamines: Selective and potent inhibitors of neuronal nitric oxide synthase

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 17, 2004, Pages 4511-4514

  Nason, Deane M ^a   Heck, Steven D ^a   Bodenstein, Mathew S ^a   Lowe III, John A ^a   Nelson, Robert B ^a   Liston, Dane R ^a   Nolan, Charles E ^a   Lanyon, Lorraine F ^a   Ward, Karen M ^a   Volkmann, Robert A ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

nNOS inhibitors

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PYRIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; SUBSTITUTION REACTION;

AMINES; ENZYME INHIBITORS; HUMANS; NERVE TISSUE PROTEINS; NEURAL INHIBITION; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PYRIDINES;

EID: 3843085237     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.06.043     Document Type: Article

References (7)

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