A homogeneous fluorescent cell-based assay for detection of heterologously expressed nitric oxide synthase activity

Journal of Biomolecular Screening

Volumn 10, Issue 8, 2005, Pages 849-855

  Wood, Michael W ^a,b   Hastings, Richard C ^a   Sygowski, Linda A ^a  

^a AstraZencca R and D Wilmington   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Cell based assay; Neuronal nitric oxide synthase; Small molecule inhibitors

Indexed keywords

ARGININE; CALCIUM ION; IONOMYCIN; N(G) NITROARGININE; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; ORNITHINE DERIVATIVE;

ARTICLE; ASSAY; CELL CLONE; CELL STRAIN HEK293; CONCENTRATION RESPONSE; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; FLUORESCENCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

CELL LINE; CLONING, MOLECULAR; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE; HUMANS; INHIBITORY CONCENTRATION 50; IONOMYCIN; KIDNEY; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; RHODAMINES; TRANSFECTION;

EID: 29144515521     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057105280640     Document Type: Article

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