Discovery of a pimaricin analog JBIR-13, from Streptomyces bicolor NBRC 12746 as predicted by sequence analysis of type i polyketide synthase gene

Applied Microbiology and Biotechnology

Volumn 83, Issue 1, 2009, Pages 127-133

  Komaki, Hisayuki ^a,b   Izumikawa, Miho ^a   Ueda, Jun Ya ^a   Nakashima, Takuji ^b   Khan, Shams Tabrez ^a,b   Takagi, Motoki ^a   Shin Ya, Kazuo ^c  

^a Koto ku   (Japan)

^b NATIONAL INSTITUTE OF TECHNOLOGY AND EVALUATION   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

JBIR 13; Pimaricin; Polyene macrolide; Streptomyces bicolor; Type I polyketide synthase

Indexed keywords

JBIR-13; PIMARICIN; POLYENE MACROLIDE; STREPTOMYCES BICOLOR; TYPE I POLYKETIDE SYNTHASE;

ABSORPTION SPECTROSCOPY; ANTIBIOTICS; ENZYMES; GENES; LIGHT ABSORPTION; ORGANIC COMPOUNDS; PLANTS (BOTANY); POLYMERS; SEWAGE TREATMENT PLANTS;

SPECTROSCOPIC ANALYSIS;

JBIR 13; MACROLIDE; NATAMYCIN; POLYENE; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; BACTERIUM; BIOACTIVITY; DRUG DEVELOPMENT; ENZYME ACTIVITY; GENE EXPRESSION; PHYLOGENETICS; SPECTROSCOPY;

AMPLICON; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CULTURE; DRUG DESIGN; DRUG STRUCTURE; GENE CLUSTER; MOLECULAR PHYLOGENY; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PROTEIN DOMAIN; SEQUENCE ANALYSIS; STREPTOMYCES; STREPTOMYCES BICOLOR; ULTRAVIOLET RADIATION; ULTRAVIOLET SPECTROSCOPY; UNINDEXED SEQUENCE;

ANTIFUNGAL AGENTS; BACTERIAL PROTEINS; CLUSTER ANALYSIS; DNA, BACTERIAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NATAMYCIN; PHYLOGENY; POLYKETIDE SYNTHASES; SEQUENCE ANALYSIS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; SPECTRUM ANALYSIS; STREPTOMYCES;

STREPTOMYCES BICOLOR;

EID: 67349167956     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-008-1849-8     Document Type: Article

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