A novel actinomycete strain de-replication approach based on the diversity of polyketide synthase and nonribosomal peptide synthetase biosynthetic pathways

Applied Microbiology and Biotechnology

Volumn 67, Issue 6, 2005, Pages 795-806

  Ayuso, Angel ^a   Clark, Desmond ^b   González, Ignacio ^a   Salazar, Oscar ^a   Anderson, Annaliesa ^b   Genilloud, Olga ^a  

^a Medical affairs Merck sharp and Dohme ltd   (Spain)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; BIOSYNTHESIS; METABOLITES; POLYPEPTIDES; STRAIN;

ACTINOMYCETES; BIOLOGICAL ACTIVITY; NONRIBOSOMAL PEPTIDE SYNTHETASES (NRPS); POLYKETIDE SYNTHASES (PKS);

ENZYMES;

PEPTIDE SYNTHASE; POLYKETIDE SYNTHASE;

ENZYME;

ACTINOBACTERIA; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATION; BIOSYNTHESIS; CONTROLLED STUDY; MICROBIAL DIVERSITY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; RIBOSOME; SOIL ANALYSIS; WILD TYPE;

ACTINOBACTERIA; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; CANDIDA ALBICANS; DNA FINGERPRINTING; GENES, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PEPTIDE SYNTHASES; POLYKETIDE SYNTHASES; POLYMERASE CHAIN REACTION; SOIL MICROBIOLOGY; TROPICAL CLIMATE; VARIATION (GENETICS);

EID: 21344453076     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-004-1828-7     Document Type: Article

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