Coagulation Factor Xa inhibits cancer cell migration via Protease-activated receptor-1 activation

Thrombosis Research

Volumn 124, Issue 2, 2009, Pages 219-225

  Borensztajn, Keren ^a,b   Bijlsma, Maarten F ^b   Reitsma, Pieter H ^b   Peppelenbosch, Maikel P ^a   Spek, C Arnold ^b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Cancer cell; Cell migration; Coagulation factor Xa; Protease activated receptor; Signaling

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; HIRUDIN; PERTUSSIS TOXIN; PROTEINASE ACTIVATED RECEPTOR 1;

ARTICLE; BLOOD CLOTTING; CANCER CELL; CANCER INHIBITION; CARCINOMA CELL; CELL INVASION; CELL LINE; CELL MIGRATION; CELL SPECIFICITY; CELL STRAIN HCT116; CELL STRAIN HT29; CELL STRAIN MCF 7; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FACTOR XA; FEMALE; FIBROBLASTS; HCT116 CELLS; HT29 CELLS; HUMANS; LUNG NEOPLASMS; RECEPTOR, PAR-1; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 67349097890     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.01.015     Document Type: Article

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