Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription

Virology

Volumn 388, Issue 1, 2009, Pages 204-211

  Sato, Yoshitaka ^a,b   Shirata, Noriko ^a   Kudoh, Ayumi ^a   Iwahori, Satoko ^a   Nakayama, Sanae ^a   Murata, Takayuki ^a   Isomura, Hiroki ^a   Nishiyama, Yukihiro ^b   Tsurumi, Tatsuya ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

BZLF1; Epstein Barr virus; Lytic infection; p53; Transcription

Indexed keywords

IMMEDIATE EARLY PROTEIN BZLF1; NUTLIN 3; PROTEIN MDM2; PROTEIN P53; UBIQUITIN PROTEIN LIGASE E3;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; EMBRYO; EPSTEIN BARR VIRUS; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TRANSGENIC MOUSE; UBIQUITINATION; VIRUS INFECTION; VIRUS REPLICATION;

ANIMALS; CELL LINE, TUMOR; DOWN-REGULATION; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRUS 4, HUMAN; HUMANS; LEUPEPTINS; MICE; PROTO-ONCOGENE PROTEINS C-MDM2; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

HUMAN HERPESVIRUS 4;

EID: 67349095745     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.03.017     Document Type: Article

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