-
1
-
-
4944230728
-
Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: A vicious cycle between bone destruction and myeloma expansion
-
Abe M. Hiura K. Wilde J. Shioyasono A. Moriyama K. Hashimoto T. Kido S. Oshima T. Shibata H. Ozaki S. Inoue D. Matsumoto T. 2004 Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion Blood 104 2484 2491
-
(2004)
Blood
, vol.104
, pp. 2484-2491
-
-
Abe, M.1
Hiura, K.2
Wilde, J.3
Shioyasono, A.4
Moriyama, K.5
Hashimoto, T.6
Kido, S.7
Oshima, T.8
Shibata, H.9
Ozaki, S.10
Inoue, D.11
Matsumoto, T.12
-
2
-
-
3442900472
-
PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism
-
Adams S. Miller G.T. Jesson M.I. Watanabe T. Jones B. Wallner B.P. 2004 PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism Cancer Research 64 5471 5480
-
(2004)
Cancer Research
, vol.64
, pp. 5471-5480
-
-
Adams, S.1
Miller, G.T.2
Jesson, M.I.3
Watanabe, T.4
Jones, B.5
Wallner, B.P.6
-
5
-
-
0642277907
-
DPPIV, seprase, and related serine peptidases in multiple cellular functions
-
Chen W.T. Kelly T. Ghersi G. 2003 DPPIV, seprase, and related serine peptidases in multiple cellular functions Current Topic in Developmental Biology 54 207 232
-
(2003)
Current Topic in Developmental Biology
, vol.54
, pp. 207-232
-
-
Chen, W.T.1
Kelly, T.2
Ghersi, G.3
-
6
-
-
0037990031
-
Tumors and their microenvironments: Tilling the soil
-
Commentary re: A. M. Scott et al, A phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer. Clinical Cancer Research, 9, 1639-1647, 2003
-
Cheng J.D. Weiner L.M. 2003 Tumors and their microenvironments: tilling the soil Commentary re: A. M. Scott et al, A phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer. Clinical Cancer Research, 9, 1639-1647, 2003 Clinical Cancer Research 9 1590 1595
-
(2003)
Clinical Cancer Research
, vol.9
, pp. 1590-1595
-
-
Cheng, J.D.1
Weiner, L.M.2
-
7
-
-
0037102412
-
Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
-
Cheng J.D. Dunbrack Jr. R.L. Valianou M. Rogatko A. Alpaugh R.K. Weiner L.M. 2002 Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model Cancer Research 62 4767 4772
-
(2002)
Cancer Research
, vol.62
, pp. 4767-4772
-
-
Cheng, J.D.1
Dunbrack Jr., R.L.2
Valianou, M.3
Rogatko, A.4
Alpaugh, R.K.5
Weiner, L.M.6
-
8
-
-
0242308942
-
Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: Evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival
-
Croucher P.I. De Hendrik R. Perry M.J. Hijzen A. Shipman C.M. Lippitt J. Green J. Van Marck E. Van Camp B. Vanderkerken K. 2003 Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival Journal of Bone and Mineral Research 18 482 492
-
(2003)
Journal of Bone and Mineral Research
, vol.18
, pp. 482-492
-
-
Croucher, P.I.1
De Hendrik, R.2
Perry, M.J.3
Hijzen, A.4
Shipman, C.M.5
Lippitt, J.6
Green, J.7
Van Marck, E.8
Van Camp, B.9
Vanderkerken, K.10
-
9
-
-
0038528630
-
The tumor microenvironment: Focus on myeloma
-
Dalton W.S. 2003 The tumor microenvironment: focus on myeloma Cancer Treatment Reviews 29 Suppl. 1 11 19
-
(2003)
Cancer Treatment Reviews
, vol.29
, Issue.1 SUPPL.
, pp. 11-19
-
-
Dalton, W.S.1
-
10
-
-
0141994805
-
Consequences of interactions between the bone marrow stroma and myeloma
-
Epstein J. Yaccoby S. 2003 Consequences of interactions between the bone marrow stroma and myeloma Hematology Journal 4 310 314
-
(2003)
Hematology Journal
, vol.4
, pp. 310-314
-
-
Epstein, J.1
Yaccoby, S.2
-
13
-
-
0031781636
-
The bone marrow stromal environment is a major factor in myeloma cell resistance to dexamethasone
-
Grigorieva I. Thomas X. Epstein J. 1998 The bone marrow stromal environment is a major factor in myeloma cell resistance to dexamethasone Experimental Hematology 26 597 603
-
(1998)
Experimental Hematology
, vol.26
, pp. 597-603
-
-
Grigorieva, I.1
Thomas, X.2
Epstein, J.3
-
14
-
-
15944389319
-
Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer
-
Huang Y. Wang S. Kelly T. 2004 Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer Cancer Research 64 2712 2716
-
(2004)
Cancer Research
, vol.64
, pp. 2712-2716
-
-
Huang, Y.1
Wang, S.2
Kelly, T.3
-
16
-
-
20444421293
-
Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): Cell-surface proteases that activate cell signaling and are potential targets for cancer therapy
-
Kelly T. 2005 Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy Drug Resistance Updates 8 51 58
-
(2005)
Drug Resistance Updates
, vol.8
, pp. 51-58
-
-
Kelly, T.1
-
17
-
-
0033609816
-
A novel protease-docking function of integrin at invadopodia
-
Mueller S.C. Ghersi G. Akiyama S.K. Sang Q.X. Howard L. Pineiro-Sanchez M. Nakahara H. Yeh Y. Chen W.T. 1999 A novel protease-docking function of integrin at invadopodia Journal of Biological Chemistry 274 24947 24952
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 24947-24952
-
-
Mueller, S.C.1
Ghersi, G.2
Akiyama, S.K.3
Sang, Q.X.4
Howard, L.5
Pineiro-Sanchez, M.6
Nakahara, H.7
Yeh, Y.8
Chen, W.T.9
-
18
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A. Homey B. Soto H. Ge N. Catron D. Buchanan M.E. McClanahan T. Murphy E. Yuan W. Wagner S.N. Barrera J.L. Mohar A. Verastegui E. Zlotnik A. 2001 Involvement of chemokine receptors in breast cancer metastasis Nature 410 50 56
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
McClanahan, T.7
Murphy, E.8
Yuan, W.9
Wagner, S.N.10
Barrera, J.L.11
Mohar, A.12
Verastegui, E.13
Zlotnik, A.14
-
19
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy G.R. 2002 Metastasis to bone: causes, consequences and therapeutic opportunities Nature Reviews Cancer 2 584 593
-
(2002)
Nature Reviews Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
20
-
-
0142157084
-
Molecular mechanisms of bone metastasis and therapeutic implications
-
O'Keefe R.J. Guise T.A. 2003 Molecular mechanisms of bone metastasis and therapeutic implications Clinical Orthopaedics 415 Suppl. S100 S104
-
(2003)
Clinical Orthopaedics
, vol.415
, Issue.SUPPL.
-
-
O'Keefe, R.J.1
Guise, T.A.2
-
21
-
-
0033579444
-
Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
-
Park J.E. Lenter M.C. Zimmermann R.N. Garin-Chesa P. Old L.J. Rettig W.J. 1999 Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts Journal of Biological Chemistry 274 36505 36512
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 36505-36512
-
-
Park, J.E.1
Lenter, M.C.2
Zimmermann, R.N.3
Garin-Chesa, P.4
Old, L.J.5
Rettig, W.J.6
-
22
-
-
0035949510
-
Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression
-
Pearse R.N. Sordillo E.M. Yaccoby S. Wong B.R. Liau D.F. Colman N. Michaeli J. Epstein J. Choi Y. 2001 Multiple myeloma disrupts the TRANCE/osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression Proceedings of the National Academy of Sciences United States of America 98 11581 11586
-
(2001)
Proceedings of the National Academy of Sciences United States of America
, vol.98
, pp. 11581-11586
-
-
Pearse, R.N.1
Sordillo, E.M.2
Yaccoby, S.3
Wong, B.R.4
Liau, D.F.5
Colman, N.6
Michaeli, J.7
Epstein, J.8
Choi, Y.9
-
24
-
-
3843069939
-
FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor
-
Ramirez-Montagut T. Blachere N.E. Sviderskaya E.V. Bennett D.C. Rettig W.J. Garin-Chesa P. Houghton A.N. 2004 FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor Oncogene 23 5435 5446
-
(2004)
Oncogene
, vol.23
, pp. 5435-5446
-
-
Ramirez-Montagut, T.1
Blachere, N.E.2
Sviderskaya, E.V.3
Bennett, D.C.4
Rettig, W.J.5
Garin-Chesa, P.6
Houghton, A.N.7
-
25
-
-
9444239192
-
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis
-
Rash-Yahana M. Pikarsky E. Abramovitch R. Zeira E. Pal B. Karplus R. Beider K. Avniel S. Kasem S. Galun E. Peled A. 2004 Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis FASEB Journal 18 1240 1242
-
(2004)
FASEB Journal
, vol.18
, pp. 1240-1242
-
-
Rash-Yahana, M.1
Pikarsky, E.2
Abramovitch, R.3
Zeira, E.4
Pal, B.5
Karplus, R.6
Beider, K.7
Avniel, S.8
Kasem, S.9
Galun, E.10
Peled, A.11
-
27
-
-
0027302568
-
Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroectodermal origin
-
Rettig W.J. Garin-Chesa P. Healey J.H. Su S.L. Ozer H.L. Schwab M. Albino A.P. Old L.J. 1993 Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroectodermal origin Cancer Research 53 3327 3335
-
(1993)
Cancer Research
, vol.53
, pp. 3327-3335
-
-
Rettig, W.J.1
Garin-Chesa, P.2
Healey, J.H.3
Su, S.L.4
Ozer, H.L.5
Schwab, M.6
Albino, A.P.7
Old, L.J.8
-
28
-
-
0036829305
-
Role of the bone marrow microenvironment in multiple myeloma
-
Roodman G.D. 2002 Role of the bone marrow microenvironment in multiple myeloma Journal of Bone and Mineral Research 17 1921 1925
-
(2002)
Journal of Bone and Mineral Research
, vol.17
, pp. 1921-1925
-
-
Roodman, G.D.1
-
31
-
-
0037989982
-
A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer
-
Scott A.M. Wiseman G. Welt S. Adjei A. Lee F.T. Hopkins W. Divgi C.R. Hanson L.H. Mitchell P. Gansen D.N. Larson S.M. Ingle J.N. Hoffman E.W. Tanswell P. Ritter G. Cohen L.S. Bette P. Arvay L. Amelsberg A. Vlock D. Rettig W.J. Old L.J. 2003 A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer Clinical Cancer Research 9 1639 1647
-
(2003)
Clinical Cancer Research
, vol.9
, pp. 1639-1647
-
-
Scott, A.M.1
Wiseman, G.2
Welt, S.3
Adjei, A.4
Lee, F.T.5
Hopkins, W.6
Divgi, C.R.7
Hanson, L.H.8
Mitchell, P.9
Gansen, D.N.10
Larson, S.M.11
Ingle, J.N.12
Hoffman, E.W.13
Tanswell, P.14
Ritter, G.15
Cohen, L.S.16
Bette, P.17
Arvay, L.18
Amelsberg, A.19
Vlock, D.20
Rettig, W.J.21
Old, L.J.22
more..
-
33
-
-
0032821644
-
CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption
-
Sun L. Adebanjo O.A. Moonga B.S. Corisdeo S. Anandatheerthavarada H.K. Biswas G. Arakawa T. Hakeda Y. Koval A. Sodam B. Bevis P.J. Moser A.J. Lai F.A. Epstein S. Troen B.R. Kumegawa M. Zaidi M. 1999 CD38/ADP-ribosyl cyclase: a new role in the regulation of osteoclastic bone resorption Journal of Cell Biology 146 1161 1172
-
(1999)
Journal of Cell Biology
, vol.146
, pp. 1161-1172
-
-
Sun, L.1
Adebanjo, O.A.2
Moonga, B.S.3
Corisdeo, S.4
Anandatheerthavarada, H.K.5
Biswas, G.6
Arakawa, T.7
Hakeda, Y.8
Koval, A.9
Sodam, B.10
Bevis, P.J.11
Moser, A.J.12
Lai, F.A.13
Epstein, S.14
Troen, B.R.15
Kumegawa, M.16
Zaidi, M.17
-
38
-
-
0642364982
-
Low cobalamin (vitamin B12) levels in multiple myeloma: A retrospective study
-
Vlasveld L.T. 2003 Low cobalamin (vitamin B12) levels in multiple myeloma: a retrospective study Netherlands Journal of Medicine 61 249 252
-
(2003)
Netherlands Journal of Medicine
, vol.61
, pp. 249-252
-
-
Vlasveld, L.T.1
-
39
-
-
27744526844
-
The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype
-
Yaccoby S. 2005 The phenotypic plasticity of myeloma plasma cells as expressed by dedifferentiation into an immature, resilient, and apoptosis-resistant phenotype Clinical Cancer Research 11 7599 7606
-
(2005)
Clinical Cancer Research
, vol.11
, pp. 7599-7606
-
-
Yaccoby, S.1
-
40
-
-
0033570946
-
The proliferative potential of myeloma plasma cells manifest in the SCID-hu host
-
Yaccoby S. Epstein J. 1999 The proliferative potential of myeloma plasma cells manifest in the SCID-hu host Blood 94 3576 3582
-
(1999)
Blood
, vol.94
, pp. 3576-3582
-
-
Yaccoby, S.1
Epstein, J.2
-
41
-
-
0032532608
-
Primary myeloma cells growing in SCID-hu mice: A model for studying the biology and treatment of myeloma and its manifestations
-
Yaccoby S. Barlogie B. Epstein J. 1998 Primary myeloma cells growing in SCID-hu mice: a model for studying the biology and treatment of myeloma and its manifestations Blood 92 2908 2913
-
(1998)
Blood
, vol.92
, pp. 2908-2913
-
-
Yaccoby, S.1
Barlogie, B.2
Epstein, J.3
-
42
-
-
0036181668
-
Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity
-
Yaccoby S. Pearse R.N. Johnson C.L. Barlogie B. Choi Y. Epstein J. 2002a Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity British Journal of Haematology 116 278 290
-
(2002)
British Journal of Haematology
, vol.116
, pp. 278-290
-
-
Yaccoby, S.1
Pearse, R.N.2
Johnson, C.L.3
Barlogie, B.4
Choi, Y.5
Epstein, J.6
-
45
-
-
33644558753
-
Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems andmyelomatous SCID-hu mice
-
Yaccoby S. Wezeman M.J. Zangari M. Walker R. Cottler-Fox M. Gaddy D. Ling W. Saha R. Barlogie B. Tricot G. Epstein J. 2006 Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems andmyelomatous SCID-hu mice Haematologica 91 53 60
-
(2006)
Haematologica
, vol.91
, pp. 53-60
-
-
Yaccoby, S.1
Wezeman, M.J.2
Zangari, M.3
Walker, R.4
Cottler-Fox, M.5
Gaddy, D.6
Ling, W.7
Saha, R.8
Barlogie, B.9
Tricot, G.10
Epstein, J.11
-
46
-
-
0036493522
-
Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
-
Zhan F. Hardin J. Kordsmeier B. Bumm K. Zheng M. Tian E. Sanderson R. Yang Y. Wilson C. Zangari M. Anaissie E. Morris C. Muwalla F. van Rhee F. Fassas A. Crowley J. Tricot G. Barlogie B. Shaughnessy J. 2002 Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells Blood 99 1745 1757
-
(2002)
Blood
, vol.99
, pp. 1745-1757
-
-
Zhan, F.1
Hardin, J.2
Kordsmeier, B.3
Bumm, K.4
Zheng, M.5
Tian, E.6
Sanderson, R.7
Yang, Y.8
Wilson, C.9
Zangari, M.10
Anaissie, E.11
Morris, C.12
Muwalla, F.13
Van Rhee, F.14
Fassas, A.15
Crowley, J.16
Tricot, G.17
Barlogie, B.18
Shaughnessy, J.19
-
47
-
-
0142094496
-
Toward the identification of distinct molecular and clinical entities of multiple myeloma using global gene expression profiling
-
Zhan F. Barlogie B. Shaughnessy J. 2003a Toward the identification of distinct molecular and clinical entities of multiple myeloma using global gene expression profiling Seminars in Hematology 40 308 320
-
(2003)
Seminars in Hematology
, vol.40
, pp. 308-320
-
-
Zhan, F.1
Barlogie, B.2
Shaughnessy, J.3
-
48
-
-
0037307238
-
Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development
-
Zhan F. Tian E. Bumm K. Smith R. Barlogie B. Shaughnessy J. 2003b Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development Blood 101 1128 1140
-
(2003)
Blood
, vol.101
, pp. 1128-1140
-
-
Zhan, F.1
Tian, E.2
Bumm, K.3
Smith, R.4
Barlogie, B.5
Shaughnessy, J.6
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