Proteomic approach to study the cytotoxicity of dioscin (saponin)

Proteomics

Volumn 6, Issue 8, 2006, Pages 2422-2432

  Wang, Ying ^a   Yim, Hing Cheung ^a   Yang, Zhiqi ^a,b   Chiu, Jen Fu ^a   Che, Chi Ming ^a   He, Qing Yu ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

Cytotoxicity; Dioscin; Drug mechanism; HL 60 cells; Mitochondria; Saponin

Indexed keywords

DIOSCIN; MITOCHONDRIAL PROTEIN; PHOSPHATASE; PLANT EXTRACT; SAPONIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL STRAIN HL 60; CHINESE MEDICINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEDICINAL PLANT; MEMBRANE POTENTIAL; MYELOID LEUKEMIA; POLYGONATUM ZANLANSCIANENSE; PRIORITY JOURNAL; PROTEOMICS; SILVER STAINING; STATISTICAL ANALYSIS; WESTERN BLOTTING;

APOPTOSIS; DIOSGENIN; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HL-60 CELLS; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; MODELS, CHEMICAL; POLYGONATUM; PROTEOMICS; SAPONINS; SILVER STAINING; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

POLYGONATUM;

EID: 33646251378     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200500595     Document Type: Article

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