Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: Activation of caspases and down-regulation of Bcl-2 protein

British Journal of Haematology

Volumn 102, Issue 4, 1998, Pages 1055-1060

  Akao, Yukihiro ^a   Mizoguchi, Hiromi ^a   Kojima, Seiji ^b   Naoe, Tomoki ^c   Ohishi, Nobuko ^d   Yagi, Kunio ^a,d  

^a GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

^b JAPANESE RED CROSS NAGOYA FIRST HOSPITAL   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Institute of Physical and Chemical Research   (Japan)

Author keywords

Apoptosis; Arsenic trioxide; Bcl 2; Caspases; Leukaemia

Indexed keywords

ARSENIC;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; B CELL LEUKEMIA; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; ARSENICALS; BLOTTING, WESTERN; DNA FRAGMENTATION; DOWN-REGULATION; ELECTROPHORESIS, AGAR GEL; HUMANS; LEUKEMIA, B-CELL; NEOPLASM PROTEINS; OXIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 0031691443     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00869.x     Document Type: Article

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