Daxx inhibits muscle differentiation by repressing E2A-mediated transcription

Journal of Cellular Biochemistry

Volumn 107, Issue 3, 2009, Pages 438-447

  Gupta, Amitabh ^a   Hou, Rong ^b,c   Liu, Liming ^b,c   Hiroyasu, Shungo ^b,c   Hadix, Jennifer A ^b   Huggins, Gordon S ^d   Sibinga, Nicholas E S ^b,c  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b Departments of Medicine (Cardiovascular Division)   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d TUFTS MEDICAL CENTER   (United States)

Author keywords

Histone deacetylase; Myogenesis; Transcriptional regulation

Indexed keywords

DAXX PROTEIN; HELIX LOOP HELIX PROTEIN; INHIBITOR OF DIFFERENTIATION PROTEIN; TRANSCRIPTION FACTOR E2A;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA BINDING; GENE CONTROL; MOUSE; MUSCLE DEVELOPMENT; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; MICE; MUSCLE FIBERS, SKELETAL; MYOBLASTS, SKELETAL; NIH 3T3 CELLS; NUCLEAR PROTEINS; RATS; TRANSCRIPTION, GENETIC;

EID: 66749192743     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22140     Document Type: Article

References (54)

1. Arnold HH, Winter B. 1998. Muscle differentiation: More complexity to the network of myogenic regulators. Curr Opin Genet Dev 8:539-544. (Pubitemid 28477356)
2. Bailey P, Downes M, Lau P, Harris J, Chen SL, Hamamori Y, Sartorelli V, Muscat GE. 1999. The nuclear receptor corepressor N-CoR regulates differentiation: N-CoR directly interacts with MyoD. Mol Endocrinol 13:1155-1168. (Pubitemid 30644303)
3. Barton K, Muthusamy N, Fischer C, Ting CN, Walunas TL, Lanier LL, Leiden JM. 1998. The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity 9:555-563. (Pubitemid 28499206)
4. Benezra R, Davis RL, Lockshon D, Turner DL, Weintraub H. 1990. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins. Cell 61:49-59. (Pubitemid 20134378)
5. Bergstrom DA, Penn BH, Strand A, Perry RL, Rudnicki MA, Tapscott SJ. 2002. Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression. Mol Cell 9:587-600. (Pubitemid 34273789)
6. Berkes CA, Tapscott SJ. 2005. MyoD and the transcriptional control of myogenesis. Semin Cell Dev Biol 16:585-595. (Pubitemid 41247882)
7. Bories JC, Willerford DM, Grevin D, Davidson L, Camus A, Martin P, Stehelin D, Alt FW. 1995. Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene. Nature 377:635-638.
8. Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. 1998. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 281:1860-1863. (Pubitemid 28450508)
9. Chi N, . Epstein JA. Getting your Pax straight: Pax proteins in development and disease. Trends Genet 18:41-47. (Pubitemid 34031857)
10. Cserjesi P, Brown D, Lyons GE, Olson EN. 1995. Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development. Dev Biol 170:664-678.
11. De los Santos M, Zambrano A, Sanchez-Pacheco A, Aranda A. 2007. Histone deacetylase inhibitors regulate retinoic acid receptor beta expression in neuroblastoma cells by both transcriptional and posttranscriptional mechanisms. Mol Endocrinol 21:2416-2426.
12. Dodou E, Xu SM, Black BL. 2003. mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivo. Mech Dev 120:1021-1032. (Pubitemid 37205045)
13. Ecsedy JA, Michaelson JS, Leder P. 2003. Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity. Mol Cell Biol 23:950-960. (Pubitemid 36133513)
14. Emelyanov AV, Kovac CR, Sepulveda MA, Birshtein BK. 2002. The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells. J Biol Chem 277:11156-11164. (Pubitemid 34952877)
15. Firulli AB. 2003. A HANDful of questions: The molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors. Gene 312:27-40. (Pubitemid 37345124)
16. Firulli BA, Hadzic DB, McDaid JR, Firulli AB. 2000. The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function. J Biol Chem 275:33567-33573.
17. Greger JG, Katz RA, Ishov AM, Maul GG, Skalka AM. 2005. The cellular protein daxx interacts with avian sarcoma virus integrase and viral DNA to repress viral transcription. J Virol 79:4610-4618. (Pubitemid 40464212)
18. Guillemot F, Lo LC, Johnson JE, Auerbach A, Anderson DJ, Joyner AL. 1993. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell 75:463-476. (Pubitemid 23335072)
19. Henthorn P, Kiledjian M, Kadesch T. 1990. Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif. Science 247:467-470. (Pubitemid 20044640)
20. Hollenbach AD, Sublett JE, McPherson CJ, Grosveld G. 1999. The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx. EMBO J 18:3702-3711. (Pubitemid 29308849)
21. Hollenbach AD, McPherson CJ, Mientjes EJ, Iyengar R, Grosveld G. 2002. Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek. J Cell Sci 115:3319-3330. (Pubitemid 34960184)
22. Hollenberg SM, Sternglanz R, Cheng PF, Weintraub H. 1995. Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol Cell Biol 15:3813-3822.
23. Iezzi S, Cossu G, Nervi C, Sartorelli V, Puri PL. 2002. Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases. Proc Natl Acad Sci USA 99:7757-7762. (Pubitemid 34568764)
24. Jang MS, Ryu SW, Kim E. 2002. Modification of Daxx by small ubiquitin-related modifier-1. Biochem Biophys Res Commun 295:495-500. (Pubitemid 34785862)
25. Jen Y, Weintraub H, Benezra R. 1992. Overexpression of Id protein inhibits the muscle differentiation program: In vivo association of Id with E2A proteins. Genes Dev 6:1466-1479.
26. Johnson JE, Wold BJ, Hauschka SD. 1989. Muscle creatine kinase sequence elements regulating skeletal and cardiac muscle expression in transgenic mice. Mol Cell Biol 9:3393-3399. (Pubitemid 19189628)
27. Kho CJ, Huggins GS, Endege WO, Patterson C, Jain MK, Lee ME, Haber E. 1997. The polymyositis-scleroderma autoantigen interacts with the helix-loop-helix proteins E12 and E47. J Biol Chem 272:13426-13431. (Pubitemid 27216777)
28. Kim EJ, Park JS, Um SJ. 2003. Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML. Nucleic Acids Res 31:5356-5367. (Pubitemid 37441904)
29. Klan N, Seuter S, Schnur N, Jung M, Steinhilber D. 2003. Trichostatin A and structurally related histone deacetylase inhibitors induce 5-lipoxygenase promoter activity. Biol Chem 384:777-785. (Pubitemid 36752617)
30. Li H, Leo C, Zhu J, Wu X, O'Neil J, Park EJ, Chen JD. 2000a. Sequestration and inhibition of Daxx-mediated transcriptional repression by PML. Mol Cell Biol 20:1784-1796. (Pubitemid 30100196)
31. Li R, Pei H, Watson DK, Papas TS. 2000b. EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes. Oncogene 19:745-753. (Pubitemid 30107705)
32. Lu J, McKinsey TA, Zhang CL, Olson EN. 2000. Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases. Mol Cell 6:233-244.
33. Mal A, Sturniolo M, Schiltz RL, Ghosh MK, Harter ML. 2001. A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: Inhibition of the myogenic program. EMBO J 20:1739-1753. (Pubitemid 32299410)
34. Massari ME, Murre C. 2000. Helix-loop-helix proteins: Regulators of transcription in eucaryotic organisms. Mol Cell Biol 20:429-440. (Pubitemid 30023084)
35. McKinsey TA, Zhang CL, Olson EN. 2001. Control of muscle development by dueling HATs and HDACs. Curr Opin Genet Dev 11:497-504. (Pubitemid 32800722)
36. Michaelson JS, Bader D, Kuo F, Kozak C, Leder P. 1999. Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development. Genes Dev 13:1918-1923. (Pubitemid 29407359)
37. Murre C, McCaw PS, Baltimore D. 1989a. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56:777-783. (Pubitemid 19082513)
38. Murre C, McCaw PS, Vaessin H, Caudy M, Jan LY, Jan YN, Cabrera CV, Buskin JN, Hauschka SD, Lassar AB. 1989b. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 58:537-544. (Pubitemid 19203538)
39. Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai MJ. 1997. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev 11:2323-2334. (Pubitemid 27408530)
40. Neuhold LA, Wold B. 1993. HLH forced dimers: Tethering MyoD to E47 generates a dominant positive myogenic factor insulated from negative regulation by Id. Cell 74:1033-1042. (Pubitemid 23289460)
41. Ordentlich P, Lin A, Shen CP, Blaumueller C, Matsuno K, Artavanis-Tsakonas S, Kadesch T. 1998. Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol Cell Biol 18:2230-2239. (Pubitemid 28152671)
42. Perlman R, Schiemann WP, Brooks MW, Lodish HF, Weinberg RA. 2001. TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation. Nat Cell Biol 3:708-714. (Pubitemid 32734248)
43. Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH. 1996. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell 86:47-57. (Pubitemid 26256577)
44. Puri PL, Sartorelli V. 2000. Regulation of muscle regulatory factors by DNA-binding, interacting proteins, and post-transcriptional modifications. J Cell Physiol 185:155-173.
45. Ranganath S, Ouyang W, Bhattarcharya D, Sha WC, Grupe A, Peltz G, Murphy KM. 1998. GATA-3-dependent enhancer activity in IL-4 gene regulation. J Immunol 161:3822-3826. (Pubitemid 28468954)
46. Ross SE, Greenberg ME, Stiles CD. 2003. Basic helix-loop-helix factors in cortical development. Neuron 39:13-25. (Pubitemid 36830945)
47. Sibinga NES, Wang H, Perrella MA, Endege WO, Patterson C, Yoshizumi M, Haber E, Lee ME. 1999. Interferon-gamma-mediated inhibition of cyclin A gene transcription is independent of individual cis-acting elements in the cyclin A promoter. J Biol Chem 274:12139-12146. (Pubitemid 129518480)
48. Sikder HA, Devlin MK, Dunlap S, Ryu B, Alani RM. 2003. Id proteins in cell growth and tumorigenesis. Cancer Cell 3:525-530. (Pubitemid 36808647)
49. Silberstein L, Webster SG, Travis M, Blau HM. 1986. Developmental progression of myosin gene expression in cultured muscle cells. Cell 46:1075-1081. (Pubitemid 17182731)
50. Urbanek P, Wang ZQ, Fetka I, Wagner EF, Busslinger M. 1994. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 79:901-912. (Pubitemid 24371980)
51. Wang DZ, Valdez MR, McAnally J, Richardson J, Olson EN. 2001. The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development. Development 128:4623-4633. (Pubitemid 33130442)
52. Weintraub H. 1993. The MyoD family and myogenesis: Redundancy, networks, and thresholds. Cell 75:1241-1244. (Pubitemid 24021898)
53. Yang X, Khosravi-Far R, Chang HY, Baltimore D. 1997. Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 89:1067-1076. (Pubitemid 127678740)
54. Yu JY, DeRuiter SL, Turner DL. 2002. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 99:6047-6052. (Pubitemid 34493262)