Preparation conditions effect on the morphology and release kinetics of biodegradable particles: A mathematical approach

Journal of Nanoscience and Nanotechnology

Volumn 9, Issue 1, 2009, Pages 467-474

  Deloge, Alexandre ^a,b   Kalaji, Nader ^a   SheibtOthmanh, Nida ^a   Lin, Victor Shengzhao ^c   Farge, Pierre ^b   Fessi, Hatem ^a  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITÉ LYON 1   (France)

^c WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Biodegradable polymers; Encapsulation; Microparticles; Model; Release mathematical rate

Indexed keywords

ALCOHOL CONCENTRATIONS; DIFFUSION COEFFICIENTS; DOUBLE EMULSIONS; MATHEMATICAL APPROACH; MICROPARTICLES; OPERATING CONDITION; PARTICLES SIZES; POLY(LACTIC-CO-GLYCOLIC ACID); PREPARATION CONDITIONS; PROCESS PARAMETERS; RELEASE KINETICS; RELEASE MATHEMATICAL RATE; RELEASE RATE; SECOND FICK'S LAW; STIRRING SPEED; WATER PHASE; WATER-IN-OIL-IN-WATER; WATER-TO-OIL RATIOS;

DIFFUSION; EMULSIFICATION; ENCAPSULATION; MATHEMATICAL MODELS; MATHEMATICAL MORPHOLOGY; PARTICLE SIZE;

BIODEGRADABLE POLYMERS;

DRUG; DRUG CARRIER;

ARTICLE; CHEMICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG FORMULATION; KINETICS; METHODOLOGY;

COMPUTER SIMULATION; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG COMPOUNDING; KINETICS; MODELS, CHEMICAL; PHARMACEUTICAL PREPARATIONS;

EID: 66649137537     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2009.J067     Document Type: Article

References (23)

1. R. A. Jam, Biomaterials 21, 2475 (2000).
2. Y. Ogawa, M. Yamamoto, H. Okada, T. Yashiki, and T. Shimamoto, Cheni. Pharm. Bull. 36, 1095 (1988).
3. H. Jeffery, S. S. Davis, and D. T. O'Hagan, Pharn,. Res. 10, 362 (1993).
4. G. Crotts and T. G. Park, J. Control. Release 35, 91(1995).
5. C. Crotts and T. O. Park, J. Microencapsul. 15, 699 (1998).
6. M. Igartua, R. M. Hemandez, A. Esquisabel, A. R. Gascon, M. B. Calvo, and J. L. Pedraz, J. Microencapsul. 14, 349 (1997).
7. Y. Y. Yang, T. S. Chung, X. L. Bai, and W. K. Chan, Chem. Eng. Sci. 55, 2223 (2000).
8. M. Takenaga, Y. Yamaguchi, A. Kitagawa, Y. Ogawa, Y. Mizushima, and R. Igarashi, J. Control. Release 79, 81(2002).
9. S. Mao, J. Xu, C. Cal, O. Germeshaus, A. Schaper, and T. Kissel, Int. J. Pharm. 334, 137 (2007).
10. H. Fessi, I. P. Marty, F. Puissieux, and I. T. Carstensen, hit. J. Pharm. 1, 265 (1978).
11. G. Ch. Charalambopoulou, E. S. Kikkinides, K. G. Papadokostaki, A. K. Stubos, and A. Th. Papaioannou, J. Control. Release 70, 309 (2001).
12. A. Ainaoui, J. Siepmann, R. Bodmeier, and J. M. Vergnaud, Eur J. Pharm. Biopharm. 51, 17 (2001).
13. N. Faisant, J. Siepman, and J. P. Benoit, Eur J. Pharm. Sci. 15, 355 (2002).
14. D. Y. Arifin, L. Y. Lee, and C. H. Wang, Adv. Drug Deliver Rev. 58, 1274 (2006).
15. J. Siepmann and N. A. Peppas, Adv. Drug Deliver Rev. 48, 139 (2001).
16. A. Charlier, B. Leclerc, and O. Couarraze, Int. J. Pharm. 200, 115 (2000).
17. N. Faisant, I. Siepmann, J. Richard, and J. P. Benoit, Eur J. Pharm. Biopharm. 56, 271(2003).
18. J. Siepmann, F. Lecomte, and R. Bodmeier, J. Control. Release 60, 379 (1999).
19. L. Lu, G. N. Stamatas, and A. G. Mikos, J. Biomed. Mater Res. 50, 440 (2000).
20. A. G. Hausberger and P. P. DeLuca, J. Pharmaceut. Biomed. 13, 747 (1995).
21. Y. Y. Yang, T. S. Chung, and N. P. Ng, Biomaterials 22, 231 (2001).
22. J. Crank, The Mathematics of Diffusion, 2nd edn., Oxford Science Publications (1975).
23. J. Panyam, M. M. Dali, S. K. Sahoo, W. Ma, S. S. Chakravarthi, G. L. Amidon, R. I. Lovy, and V. Labhasetwar, J. Control. Release 92, 173 (2003).