Tuberculosis and host metabolism: ancient associations, fresh insights

Translational Research

Volumn 154, Issue 1, 2009, Pages 7-14

  Blumenthal, Antje ^a   Isovski, Flonza ^a   Rhee, Kyu Y ^a  

^a Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; GLUCOCORTICOID RECEPTOR; HORMONE RECEPTOR; INSULIN RECEPTOR; LIVER X RECEPTOR; NUCLEAR HORMONE RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENE EXPRESSION; GENE FUNCTION; HOST RESISTANCE; HUMAN; INSULIN RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; TUBERCULOSIS; VITAMIN DEFICIENCY;

EID: 66649095309     PISSN: 19315244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trsl.2009.04.004     Document Type: Review

References (69)

1. Cegielski J.P., and McMurray D.N. The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals. Int J Tuberc Lung Dis 8 (2004) 286-298
2. Leitch I. Diet and tuberculosis. Proc Nutr Soc (1945) 3
3. Scrimshaw N.S., Taylor C.E., and Gordon J.E. Interactions of nutrition and infection. Monograph series 57 (1968) 3-329
4. Chan J., Tian Y., Tanaka K.E., et al. Effects of protein calorie malnutrition on tuberculosis in mice. Proc Nat Acad Sci U S A 93 (1996) 14857-14861
5. Rook G.A., Taverne J., Leveton C., and Steele J. The role of gamma-interferon, vitamin D3 metabolites and tumour necrosis factor in the pathogenesis of tuberculosis. Immunology 62 (1987) 229-234
6. Rook G.A., Steele J., Fraher L., et al. Vitamin D3, gamma interferon, and control of proliferation of Mycobacterium tuberculosis by human monocytes. Immunology 57 (1986) 159-163
7. Crowle A.J., Ross E.J., and May M.H. Inhibition by 1,25(OH)2-vitamin D3 of the multiplication of virulent tubercle bacilli in cultured human macrophages. Infect Immun 55 (1987) 2945-2950
8. Shoelson S.E., Lee J., and Goldfine A.B. Inflammation and insulin resistance. J Clin Invest 116 (2006) 1793-1801
9. Castrillo A., and Tontonoz P. Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation. Annu Rev Cell Dev Biol 20 (2004) 455-480
10. Wellen K.E., and Hotamisligil G.S. Inflammation, stress, and diabetes. J Clin Invest 115 (2005) 1111-1119
11. Bruce R.M., and Wise L. Tuberculosis after jejunoileal bypass for obesity. Ann Int Med 87 (1977) 574-576
12. Thorn P.A., Brookes V.S., and Waterhouse J.A. Peptic ulcer, partial gastrectomy, and pulmonary tuberculosis. Br Med J 1 (1956) 603-608
13. Getz H.R., Long E.R., and Henderson H.J. A study of the relation of nutrition to the development of tuberculosis; influence of ascorbic acid and vitamin A. Am Rev Tuberc 64 (1951) 381-393
14. Wilkinson R.J., Llewelyn M., Toossi Z., et al. Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. Lancet 355 (2000) 618-621
15. Downes J. An experiment in the control of tuberculosis among Negroes. Milbank Mem Fund Q 28 (1950) 127-159
16. Karyadi E., West C.E., Schultink W., et al. A double-blind, placebo-controlled study of vitamin A and zinc supplementation in persons with tuberculosis in Indonesia: effects on clinical response and nutritional status. Am J Clin Nutr 75 (2002) 720-727
17. Abba K., Sudarsanam T.D., Grobler L., and Volmink J. Nutritional supplements for people being treated for active tuberculosis. Cochrane Database Syst Rev 4 (2008) CD006086
18. Crowle A.J., and Ross E.J. Inhibition by retinoic acid of multiplication of virulent tubercle bacilli in cultured human macrophages. Infect Immun 57 (1989) 840-844
19. Sly L.M., Lopez M., Nauseef W.M., and Reiner N.E. 1alpha,25-Dihydroxyvitamin D3-induced monocyte antimycobacterial activity is regulated by phosphatidylinositol 3-kinase and mediated by the NADPH-dependent phagocyte oxidase. J Biol Chem 276 (2001) 35482-35493
20. Liu P.T., Stenger S., Li H., et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311 (2006) 1770-1773
21. Rockett K.A., Brookes R., Udalova I., Vidal V., Hill A.V., and Kwiatkowski D. 1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect Immun 66 (1998) 5314-5321
22. Denis M. Killing of Mycobacterium tuberculosis within human monocytes: activation by cytokines and calcitriol. Clin Exp Immunol 84 (1991) 200-206
23. Valledor A.F., and Ricote M. Nuclear receptor signaling in macrophages. Biochem Pharmacol 67 (2004) 201-212
24. Glass C.K., and Ogawa S. Combinatorial roles of nuclear receptors in inflammation and immunity. Nature Rev 6 (2006) 44-55
25. Jiang C., Ting A.T., and Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391 (1998) 82-86
26. Ricote M., Li A.C., Willson T.M., Kelly C.J., and Glass C.K. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391 (1998) 79-82
27. Ogawa S., Lozach J., Benner C., et al. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell 122 (2005) 707-721
28. Ogawa D., Stone J.F., Takata Y., et al. Liver x receptor agonists inhibit cytokine-induced osteopontin expression in macrophages through interference with activator protein-1 signaling pathways. Circ Res 96 (2005) e59-e67
29. Joseph S.B., Bradley M.N., Castrillo A., et al. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell 119 (2004) 299-309
30. Valledor A.F., Hsu L.C., Ogawa S., Sawka-Verhelle D., Karin M., and Glass C.K. Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc Nat Acad Sci U S A 101 (2004) 17813-17818
31. Reddy R.C., Keshamouni V.G., Jaigirdar S.H., et al. Deactivation of murine alveolar macrophages by peroxisome proliferator-activated receptor-gamma ligands. Am J Physiol Lung Cell Mol Physiol 286 (2004) L613-L619
32. Anand P.K., and Kaul D. Vitamin D3-dependent pathway regulates TACO gene transcription. Biochemical and biophysical research communications 310 (2003) 876-877
33. Ferrari G., Langen H., Naito M., and Pieters J. A coat protein on phagosomes involved in the intracellular survival of mycobacteria. Cell 97 (1999) 435-447
34. Flynn J.L., and Chan J. Immunology of tuberculosis. Ann Rev Immunol 19 (2001) 93-129
35. Dzhagalov I., Chambon P., and He Y.W. Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma. J Immunol 178 (2007) 2113-2121
36. Colizzi V., and Malkovsky M. Augmentation of interleukin-2 production and delayed hypersensitivity in mice infected with Mycobacterium bovis and fed a diet supplemented with vitamin A acetate. Infect Immun 48 (1985) 581-583
37. Hernandez-Frontera E., and McMurray D.N. Dietary vitamin D affects cell-mediated hypersensitivity but not resistance to experimental pulmonary tuberculosis in guinea pigs. Infect Immun 61 (1993) 2116-2121
38. Feinstein R., Kanety H., Papa M.Z., Lunenfeld B., and Karasik A. Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. J Biol Chem 268 (1993) 26055-26058
39. Hotamisligil G.S., Shargill N.S., and Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259 (1993) 87-91
40. Paz K., Hemi R., LeRoith D., et al. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J Biol Chem 272 (1997) 29911-29918
41. Aguirre V., Werner E.D., Giraud J., Lee Y.H., Shoelson S.E., and White M.F. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem 277 (2002) 1531-1537
42. Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., and Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271 (1996) 665-668
43. Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., and Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95 (1995) 2409-2415
44. Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., and Ferrante Jr. A.W. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112 (2003) 1796-1808
45. Fukuhara A., Matsuda M., Nishizawa M., et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 307 (2005) 426-430
46. Shimomura I., Funahashi T., Takahashi M., et al. Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med 2 (1996) 800-803
47. Steppan C.M., Bailey S.T., Bhat S., et al. The hormone resistin links obesity to diabetes. Nature 409 (2001) 307-312
48. Fried S.K., Bunkin D.A., and Greenberg A.S. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrin Metab 83 (1998) 847-850
49. Chandra R.K. Cell-mediated immunity in genetically obese C57BL/6J ob/ob) mice. Am J Clin Nutr 33 (1980) 13-16
50. Farooqi I.S., Matarese G., Lord G.M., et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 110 (2002) 1093-1103
51. Fernandes G., Handwerger B.S., Yunis E.J., and Brown D.M. Immune response in the mutant diabetic C57BL/Ks-dt+ mouse. Discrepancies between in vitro and in vivo immunological assays. J Clin Invest 61 (1978) 243-250
52. Netea M.G., Joosten L.A., Lewis E., et al. Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nat Med 12 (2006) 650-656
53. Zick Y. Role of Ser/Thr kinases in the uncoupling of insulin signaling. Int J Obes Relat Metab Disord 27 (2003) S56-S60
54. Rui L., Yuan M., Frantz D., Shoelson S., and White M.F. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem 277 (2002) 42394-42398
55. Warwick M.T. Pulmonary tuberculosis and diabetes mellitus. Q J Med 26 (1957) 31-42
56. In: Younger D., Hadley W.B., Marble A., White P., Bradley R.F., and Krall L.P. (Eds). Joslin's diabetes mellitus. 11th ed (1971), Lea & Febiger, Philadelphia, Pa 628-631
57. Root H.F. The association of diabetes and tuberculosis. N Engl J Med 1 (1934) 210-213
58. Pablos-Mendez A., Blustein J., and Knirsch C.A. The role of diabetes mellitus in the higher prevalence of tuberculosis among Hispanics. Am J Public Health 87 (1997) 574-579
59. Lee M.S., Leung C.C., Kam K.M., et al. Early and late tuberculosis risks among close contacts in Hong Kong. Int J Tuberc Lung Dis 12 (2008) 281-287
60. Leung C.C., Lam T.H., Chan W.M., et al. Diabetic control and risk of tuberculosis: a cohort study. Am J Epidemiol 167 (2008) 1486-1494
61. Restrepo B.I., Fisher-Hoch S.P., Crespo J.G., et al. Type 2 diabetes and tuberculosis in a dynamic bi-national border population. Epidemiol Infect 135 (2007) 483-491
62. Alisjahbana B., van Crevel R., Sahiratmadja E., et al. Diabetes mellitus is strongly associated with tuberculosis in Indonesia. Int J Tuberc Lung Dis 10 (2006) 696-700
63. Wieland C.W., Florquin S., Chan E.D., et al. Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice. Int Immunol 17 (2005) 1399-1408
64. Martens G.W., Arikan M.C., Lee J., Ren F., Greiner D., and Kornfeld H. Tuberculosis susceptibility of diabetic mice. Am J Respir Cell Mol Biol 37 (2007) 518-524
65. Martens G.W., Arikan M.C., Lee J., Ren F., Vallerskog T., and Kornfeld H. Hypercholesterolemia impairs immunity to tuberculosis. Infect Immun 76 (2008) 3464-3472
66. World Health Organization. Global tuberculosis contol: surveillance, planning, financing (2007), World Health Organization, Geneva, Switzerland
67. de Lera A.R., Bourguet W., Altucci L., and Gronemeyer H. Design of selective nuclear receptor modulators: RAR and RXR as a case study. Nat Rev Drug Discov 6 (2007) 811-820
68. Altucci L., Leibowitz M.D., Ogilvie K.M., de Lera A.R., and Gronemeyer H. RAR and RXR modulation in cancer and metabolic disease. Nat Rev Drug Discov 6 (2007) 793-810
69. Stalenhoef J.E., Alisjahbana B., Nelwan E.J., et al. The role of interferon-gamma in the increased tuberculosis risk in type 2 diabetes mellitus. Eur J Clin Microbiol Infect Dis 27 (2008) 97-103