-
1
-
-
0015076322
-
Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits
-
Brighton CT, Heppenstall RB. 1971. Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits. J Bone Joint Surg Am 53:719-728.
-
(1971)
J Bone Joint Surg Am
, vol.53
, pp. 719-728
-
-
Brighton, C.T.1
Heppenstall, R.B.2
-
2
-
-
0016855489
-
Measurement of pH and ionic composition of pericellular sites
-
Silver IA. 1975. Measurement of pH and ionic composition of pericellular sites. Philos Trans R Soc Lond B Biol Sci 271:261-272.
-
(1975)
Philos Trans R Soc Lond B Biol Sci
, vol.271
, pp. 261-272
-
-
Silver, I.A.1
-
3
-
-
0027299685
-
Osteoarthritis in the human knee: A dynamic process of cartilage matrix degradation, synthesis and reorganization
-
Poole AR, Rizkalla G, Ionescu M, et al. 1993. Osteoarthritis in the human knee: a dynamic process of cartilage matrix degradation, synthesis and reorganization. Agents Actions Suppl 39:3-13. (Pubitemid 23196706)
-
(1993)
Agents and Actions
, vol.39
, Issue.SUPPL.
, pp. 3-13
-
-
Poole, A.R.1
Rizkalla, G.2
Ionescu, M.3
Reiner, A.4
Brooks, E.5
Rorabeck, C.6
Bourne, R.7
Bogoch, E.8
-
4
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza GL, Wang GL. 1992. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12:5447-5454.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
5
-
-
0036469146
-
Transcription. Oxygen sensing gets a second wind
-
Bruick RK, McKnight SL. 2002. Transcription. Oxygen sensing gets a second wind. Science 295:807-808.
-
(2002)
Science
, vol.295
, pp. 807-808
-
-
Bruick, R.K.1
McKnight, S.L.2
-
6
-
-
0029781622
-
Hypoxia signalling in the control of erythropoietin gene expression in rat hepatocytes
-
DOI 10.1002/(SICI)1097-4652(199608)168:2<354::AID-JCP14>3.0.CO;2-3
-
Gopfert T, Gess B, Eckardt KU, et al. 1996. Hypoxia signalling in the control of erythropoietin gene expression in rat hepatocytes. J Cell Physiol 168:354-361. (Pubitemid 26308747)
-
(1996)
Journal of Cellular Physiology
, vol.168
, Issue.2
, pp. 354-361
-
-
Gopfert, T.1
Gess, B.2
Eckardt, K.-U.3
Kurtz, A.4
-
8
-
-
0035651033
-
Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: Implications for HIF-1alpha gene therapy
-
Hofer T, Desbaillets I, Hopfl G, et al. 2001. Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy. FASEB J 15:2715-2717.
-
(2001)
FASEB J
, vol.15
, pp. 2715-2717
-
-
Hofer, T.1
Desbaillets, I.2
Hopfl, G.3
-
9
-
-
0035812772
-
2, and the 3 PHDs: How animal cells signal hypoxia to the nucleus
-
DOI 10.1016/S0092-8674(01)00518-9
-
Semenza GL. 2001. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus.[comment]. Cell 107:1-3. (Pubitemid 32972030)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 1-3
-
-
Semenza, G.L.1
-
10
-
-
33144461484
-
The role of HIF-1α in maintaining cartilage homeostasis and during the pathogenesis of osteoarthritis
-
DOI 10.1186/ar1894
-
Pfander D, Swoboda B, Cramer T. 2006. The role of HIF-1alpha in maintaining cartilage homeostasis and during the pathogenesis of osteoarthritis. Arthritis Res Ther 8:104. (Pubitemid 43264488)
-
(2006)
Arthritis Research and Therapy
, vol.8
, Issue.1
, pp. 104
-
-
Pfander, D.1
Swoboda, B.2
Cramer, T.3
-
11
-
-
0038325620
-
HIF-1α controls extracellular matrix synthesis by epiphyseal chondrocytes
-
DOI 10.1242/jcs.00385
-
Pfander D, Cramer T, Schipani E, et al. 2003. HIF-1alpha controls extracellular matrix synthesis by epiphyseal chondrocytes. J Cell Sci 116:1819-1826. (Pubitemid 36582168)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.9
, pp. 1819-1826
-
-
Pfander, D.1
Cramer, T.2
Schipani, E.3
Johnson, R.S.4
-
12
-
-
2542644319
-
Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development
-
DOI 10.1242/dev.01138
-
Pfander D, Kobayashi T, Knight MC, et al. 2004. Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development 131:2497-2508. (Pubitemid 38877655)
-
(2004)
Development
, vol.131
, Issue.10
, pp. 2497-2508
-
-
Pfander, D.1
Kobayashi, T.2
Knight, M.C.3
Zelzer, E.4
Chan, D.A.5
Olsen, B.R.6
Giaccia, A.J.7
Johnson, R.S.8
Haase, V.H.9
Schipani, E.10
-
13
-
-
26844453326
-
Tonic activation of hypoxia-inducible factor 1α in avascular articular cartilage and implications for metabolic homeostasis
-
DOI 10.1002/art.21346
-
Brucker PU, Izzo NJ, Chu CR. 2005. Tonic activation of hypoxia-inducible factor 1alpha in avascular articular cartilage and implications for metabolic homeostasis. Arthritis Rheum 52:3181-3191. (Pubitemid 41447101)
-
(2005)
Arthritis and Rheumatism
, vol.52
, Issue.10
, pp. 3181-3191
-
-
Brucker, P.U.1
Izzo, N.J.2
Chu, C.R.3
-
14
-
-
0035006740
-
Modulation of bovine articular chondrocyte gene expression in vitro by oxygen tension
-
DOI 10.1053/joca.2000.0396
-
Grimshaw MJ, Mason RM. 2001. Modulation of bovine articular chondrocyte gene expression in vitro by oxygen tension. Osteoarthritis Cartilage 9:357-364. (Pubitemid 32454779)
-
(2001)
Osteoarthritis and Cartilage
, vol.9
, Issue.4
, pp. 357-364
-
-
Grimshaw, M.J.1
Mason, R.M.2
-
15
-
-
0036158388
-
Redifferentiation of dedifferentiated bovine articular chondrocytes in alginate culture under low oxygen tension
-
DOI 10.1053/joca.2001.0477
-
Domm C, Schunke M, Christesen K, et al. 2002. Redifferentiation of dedifferentiated bovine articular chondrocytes in alginate culture under low oxygen tension. Osteoarthritis Cartilage 10:13-22. (Pubitemid 34120986)
-
(2002)
Osteoarthritis and Cartilage
, vol.10
, Issue.1
, pp. 13-22
-
-
Domm, C.1
Schunke, M.2
Christesen, K.3
Kurz, B.4
-
16
-
-
33746738858
-
Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: Possible influence of low oxygen levels
-
DOI 10.2353/ajpath.2006.050738
-
Grimmer C, Balbus N, Lang U, et al. 2006. Regulation of Type II Collagen Synthesis during Osteoarthritis by Prolyl-4-Hydroxylases: Possible Influence of Low Oxygen Levels. Am J Pathol 169:491-502. (Pubitemid 44159925)
-
(2006)
American Journal of Pathology
, vol.169
, Issue.2
, pp. 491-502
-
-
Grimmer, C.1
Balbus, N.2
Lang, U.3
Aigner, T.4
Cramer, T.5
Muller, L.6
Swoboda, B.7
Pfander, D.8
-
17
-
-
0019764206
-
Proteoglycans: Their structure, interactions and molecular organization in cartilage
-
Hardingham T. 1981. Proteoglycans: their structure, interactions and molecular organization in cartilage. Biochem Soc Trans 9:489-497.
-
(1981)
Biochem Soc Trans
, vol.9
, pp. 489-497
-
-
Hardingham, T.1
-
18
-
-
0024382294
-
Structure and biology of cartilage and bone matrix noncollagenous macromolecules
-
Heinegard D, Oldberg A. 1989. Structure and biology of cartilage and bone matrix noncollagenous macromolecules. FASEB J 3:2042-2051. (Pubitemid 19187613)
-
(1989)
FASEB Journal
, vol.3
, Issue.9
, pp. 2042-2051
-
-
Heinegard, D.1
Oldberg, A.2
-
19
-
-
0028227532
-
Structure and function of cartilage collagens
-
DOI 10.1002/jemt.1070280504
-
Bruckner P, van der Rest M. 1994. Structure and function of cartilage collagens. Microsc Res Tech 28:378-384. (Pubitemid 24222669)
-
(1994)
Microscopy Research and Technique
, vol.28
, Issue.5
, pp. 378-384
-
-
Bruckner, P.1
Van Der Rest, M.2
-
20
-
-
55349109288
-
Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality
-
DOI: 10.1016/j.joca.2008.04.007
-
Koay EJ, Athanasiou KA. 2008. Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality. Osteoarthritis Cartilage p DOI: 10.1016/j.joca.2008.04.007.
-
(2008)
Osteoarthritis Cartilage
-
-
Koay, E.J.1
Athanasiou, K.A.2
-
21
-
-
8444231259
-
Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes
-
DOI 10.1002/art.20596
-
Martin G, Andriamanalijaona R, Grassel S, et al. 2004. Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes. Arthritis Rheum 50:3549-3560. (Pubitemid 39488680)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.11
, pp. 3549-3560
-
-
Martin, G.1
Andriamanalijaona, R.2
Grassel, S.3
Dreier, R.4
Mathy-Hartert, M.5
Bogdanowicz, P.6
Boumediene, K.7
Henrotin, Y.8
Bruckner, P.9
Pujol, J.-P.10
-
22
-
-
0037255442
-
A novel two-step method for the formation of tissue-engineered cartilage by mature bovine chondrocytes: The alginate-recovered-chondrocyte (ARC) method
-
DOI 10.1016/S0736-0266(02)00109-2, PII S0736026602001092
-
Masuda K, Sah RL, Hejna MJ, et al. 2003. A novel two-step method for the formation of tissue-engineered cartilage by mature bovine chondrocytes: the alginate-recovered-chondrocyte (ARC) method. J Orthop Res 21:139-148. (Pubitemid 36157631)
-
(2003)
Journal of Orthopaedic Research
, vol.21
, Issue.1
, pp. 139-148
-
-
Masuda, K.1
Sah, R.L.2
Hejna, M.J.3
Thonar, E.J.-M.A.4
-
23
-
-
22144463885
-
Adenoviral-mediated transfer of TGF-β1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures
-
DOI 10.1016/j.exphem.2005.05.010, PII S0301472X05002237
-
Kawamura K, Chu CR, Sobajima S, et al. 2005. Adenoviral-mediated transfer of TGF-beta1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures. Exper Hematol 33:865-872. (Pubitemid 40982652)
-
(2005)
Experimental Hematology
, vol.33
, Issue.8
, pp. 865-872
-
-
Kawamura, K.1
Chu, C.R.2
Sobajima, S.3
Robbins, P.D.4
Fu, F.H.5
Izzo, N.J.6
Niyibizi, C.7
-
24
-
-
0026196246
-
Localization of type X collagen in canine growth plate and adult canine articular cartilage
-
Gannon JM, Walker G, Fischer M, et al. 1991. Localization of type X collagen in canine growth plate and adult canine articular cartilage. J Orthop Res 9:485-494.
-
(1991)
J Orthop Res
, vol.9
, pp. 485-494
-
-
Gannon, J.M.1
Walker, G.2
Fischer, M.3
-
25
-
-
0033712592
-
Nitric oxide inhibits chondrocyte response to IGF-I: Inhibition of IGF-IRbeta tyrosine phosphorylation
-
Studer RK, Levicoff E, Georgescu H, et al. 2000. Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation. Am J Physiol Cell Physiol 279:C961-969.
-
(2000)
Am J Physiol Cell Physiol
, vol.279
-
-
Studer, R.K.1
Levicoff, E.2
Georgescu, H.3
-
26
-
-
0034982488
-
Combination of reduced oxygen tension and intermittent hydrostatic pressure: A useful tool in articular cartilage tissue engineering
-
DOI 10.1016/S0021-9290(01)00050-1, PII S0021929001000501
-
Hansen U, Schunke M, Domm C, et al. 2001. Combination of reduced oxygen tension and intermittent hydrostatic pressure: a useful tool in articular cartilage tissue engineering. J Biomech 34:941-949. (Pubitemid 32530061)
-
(2001)
Journal of Biomechanics
, vol.34
, Issue.7
, pp. 941-949
-
-
Hansen, U.1
Schunke, M.2
Domm, C.3
Ioannidis, N.4
Hassenpflug, J.5
Gehrke, T.6
Kurz, B.7
-
27
-
-
4544278143
-
Tissue engineering of articular cartilage under the influence of collagen I/III membranes and low oxygen tension
-
DOI 10.1089/ten.2004.10.1277
-
Kurz B, Domm C, Jin M, et al. 2004. Tissue engineering of articular cartilage under the influence of collagen I/III membranes and low oxygen tension. Tissue Eng 10:1277-1286. (Pubitemid 39223804)
-
(2004)
Tissue Engineering
, vol.10
, Issue.7-8
, pp. 1277-1286
-
-
Kurz, B.1
Domm, C.2
Jin, M.3
Sellckau, R.4
Schunke, M.5
-
28
-
-
14044269226
-
Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: Implications for cell-based transplantation therapy
-
DOI 10.1097/01.brs.0000146462.92171.7f
-
Risbud MV, Albert TJ, Guttapalli A, et al. 2004. Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy. Spine 29:2627-2632. (Pubitemid 40353248)
-
(2004)
Spine
, vol.29
, Issue.23
, pp. 2627-2632
-
-
Risbud, M.V.1
Albert, T.J.2
Guttapalli, A.3
Vresilovic, E.J.4
Hillibrand, A.S.5
Vaccaro, A.R.6
Shapiro, I.M.7
-
29
-
-
0037033095
-
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
-
DOI 10.1074/jbc.M204938200
-
Miyazaki K, Kawamoto T, Tanimoto K, et al. 2002. Identi- fication of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J Biol Chem 277:47014-47021. (Pubitemid 36159208)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.49
, pp. 47014-47021
-
-
Miyazaki, K.1
Kawamoto, T.2
Tanimoto, K.3
Nishiyama, M.4
Honda, H.5
Kato, Y.6
-
30
-
-
22144449952
-
Synoviocytes, not chondrocytes, release free radicals after cycles of anoxia/re-oxygenation
-
DOI 10.1016/j.bbrc.2005.06.147, PII S0006291X0501380X
-
Schneider N, Mouithys-Mickalad AL, Lejeune JP, et al. 2005. Synoviocytes, not chondrocytes, release free radicals after cycles of anoxia/re-oxygenation. Biochem Biophys Res Commun 334:669-673. (Pubitemid 40982418)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.334
, Issue.2
, pp. 669-673
-
-
Schneider, N.1
Mouithys-Mickalad, A.L.2
Lejeune, J.-P.3
Deby-Dupont, G.P.4
Hoebeke, M.5
Serteyn, D.A.6
-
31
-
-
0025740098
-
Superoxide dismutase and catalase activities in the growth cartilage: Relationship between oxidoreductase activity and chondrocyte maturation
-
Matsumoto H, Silverton SF, Debolt K, et al. 1991. Superoxide dismutase and catalase activities in the growth cartilage: relationship between oxidoreductase activity and chondrocyte maturation. J Bone Miner Res 6:569-574.
-
(1991)
J Bone Miner Res
, vol.6
, pp. 569-574
-
-
Matsumoto, H.1
Silverton, S.F.2
Debolt, K.3
-
32
-
-
0021882509
-
Hydrogen peroxide suppresses the proteoglycan synthesis of intact articular cartilage
-
Schalkwijk J, van den Berg WB, van de Putte LB, et al. 1985. Hydrogen peroxide suppresses the proteoglycan synthesis of intact articular cartilage. J Rheumatol 12:205-210. (Pubitemid 15025355)
-
(1985)
Journal of Rheumatology
, vol.12
, Issue.2
, pp. 205-210
-
-
Schalkwijk, J.1
Van Den Berg, W.B.2
Van De Putte, L.B.A.3
Joosten, L.A.B.4
-
33
-
-
0027418625
-
Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes
-
Dawson TL, Gores GJ, Nieminen AL, et al. 1993. Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes. Am J Physiol 264:C961-967.
-
(1993)
Am J Physiol
, vol.264
-
-
Dawson, T.L.1
Gores, G.J.2
Nieminen, A.L.3
-
34
-
-
0029092846
-
Effect of hypoxia and reoxygenation on the formation and release of reactive oxygen species by porcine pulmonary artery endothelial cells
-
Yang W, Block ER. 1995. Effect of hypoxia and reoxygenation on the formation and release of reactive oxygen species by porcine pulmonary artery endothelial cells. J Cell Physiol 164:414-423.
-
(1995)
J Cell Physiol
, vol.164
, pp. 414-423
-
-
Yang, W.1
Block, E.R.2
-
35
-
-
0035499204
-
Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival
-
Schipani E, Ryan HE, Didrickson S, et al. 2001. Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev 15:2865-2876. (Pubitemid 33042056)
-
(2001)
Genes and Development
, vol.15
, Issue.21
, pp. 2865-2876
-
-
Schipani, E.1
Ryan, H.E.2
Didrickson, S.3
Kobayashi, T.4
Knight, M.5
Johnson, R.S.6
-
36
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, et al. 2001. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. [see comment]. Science 292:468-472. (Pubitemid 32335942)
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Von Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
37
-
-
33645875617
-
Effects of overexpression of basic helix-loop-helix transcription factor Dec1 on osteogenic and adipogenic differentiation of mesenchymal stem cells
-
Iwata T, Kawamoto T, Sasabe E, et al. 2006. Effects of overexpression of basic helix-loop-helix transcription factor Dec1 on osteogenic and adipogenic differentiation of mesenchymal stem cells. Eur J Cell Biol 85:423-431.
-
(2006)
Eur J Cell Biol
, vol.85
, pp. 423-431
-
-
Iwata, T.1
Kawamoto, T.2
Sasabe, E.3
-
38
-
-
23844493183
-
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9
-
DOI 10.1016/j.bone.2005.04.040, PII S8756328205002085
-
Robins JC, Akeno N, Mukherjee A, et al. 2005. Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone 37:313-322. (Pubitemid 41160490)
-
(2005)
Bone
, vol.37
, Issue.3
, pp. 313-322
-
-
Robins, J.C.1
Akeno, N.2
Mukherjee, A.3
Dalal, R.R.4
Aronow, B.J.5
Koopman, P.6
Clemens, T.L.7
-
39
-
-
1842788526
-
Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes
-
DOI 10.1016/j.joca.2003.12.005
-
Coimbra IB, Jimenez SA, Hawkins DF, et al. 2004. Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes. Osteoarthritis Cartilage 12:336-345. (Pubitemid 38461296)
-
(2004)
Osteoarthritis and Cartilage
, vol.12
, Issue.4
, pp. 336-345
-
-
Coimbra, I.B.1
Jimenez, S.A.2
Hawkins, D.F.3
Piera-Velazquez, S.4
Stokes, D.G.5
-
40
-
-
13844264371
-
Hypoxia and HIF-1alpha in osteoarthritis
-
Pfander D, Cramer T, Swoboda B. 2005. Hypoxia and HIF-1alpha in osteoarthritis. Int Orthop 29:6-9.
-
(2005)
Int Orthop
, vol.29
, pp. 6-9
-
-
Pfander, D.1
Cramer, T.2
Swoboda, B.3
-
41
-
-
25144514862
-
Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: Involvement of HIF-1 alpha in the pathogenesis of osteoarthritis
-
Yudoh K, Nakamura H, Masuko-Hongo K, et al. 2005. Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis. Arthritis Res Ther 7:R904-914.
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Yudoh, K.1
Nakamura, H.2
Masuko-Hongo, K.3
|