Conserved amino acid networks involved in antibody variable domain interactions

Proteins: Structure, Function and Bioinformatics

Volumn 76, Issue 1, 2009, Pages 99-114

  Wang, Norman ^a   Smith, William F ^a   Miller, Brian R ^a   Aivazian, Dikran ^a   Lugovskoy, Alexey A ^a   Reff, Mitchell E ^a   Glaser, Scott M ^a   Croner, Lisa J ^a   Demarest, Stephen J ^a  

^a BIOGEN   (United States)

Author keywords

Antibody engineering; Covariation; Ig fold; Immunoglobulin variable domain; V class

Indexed keywords

AMINO ACID; ANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; ARTIODACTYLA; BINDING AFFINITY; BINDING SITE; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; COVARIANCE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE DATABASE; STATISTICAL ANALYSIS;

AMINO ACID SEQUENCE; ANTIBODIES; CONSERVED SEQUENCE; DATABASES, PROTEIN; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; PROTEIN FOLDING; SEQUENCE ALIGNMENT;

CAMELIDAE;

EID: 66249116994     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22319     Document Type: Article

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