Sleep and neurofunctions throughout child development: Lasting effects of early iron deficiency

Journal of Pediatric Gastroenterology and Nutrition

Volumn 48, Issue SUPPL. 1, 2009, Pages

  Peirano, Patricio D ^a   Algarín, Cecilia R ^a   Chamorro, Rodrigo ^a   Reyes, Sussanne ^a   Garrido, Marcelo I ^a   Duran, Samuel ^a   Lozoff, Betsy ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Childhood; Infancy; Iron deficiency anemia; Neurofunctions; Sleep

Indexed keywords

ARTICLE; CHILD; CHILD DEVELOPMENT; COGNITION; HUMAN; IRON DEFICIENCY; IRON DEFICIENCY ANEMIA; IRON THERAPY; MENTAL DEVELOPMENT; MOTOR ACTIVITY; MOTOR DEVELOPMENT; NEUROTRANSMISSION; PRIORITY JOURNAL; SLEEP; SLEEP WAKING CYCLE; BLOOD; DRUG EFFECT; EVOKED AUDITORY RESPONSE; EVOKED VISUAL RESPONSE; INFANT; INFANT NUTRITION; IRON INTAKE; NERVOUS SYSTEM FUNCTION; NEWBORN; NUTRITIONAL STATUS; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESCHOOL CHILD; REACTION TIME; REVIEW; SLEEP DISORDER;

IRON;

ANEMIA, IRON-DEFICIENCY; CHILD DEVELOPMENT; CHILD, PRESCHOOL; EVOKED POTENTIALS, AUDITORY; EVOKED POTENTIALS, VISUAL; HUMANS; INFANT; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; IRON; IRON, DIETARY; NERVOUS SYSTEM PHYSIOLOGICAL PHENOMENA; NUTRITIONAL STATUS; REACTION TIME; SLEEP DISORDERS;

EID: 66149145506     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31819773b     Document Type: Article

References (64)

1. Stoltzfus RJ, Mullany L, Black RE. Iron deficiency anaemia. In: Ezzati M, Lopez AD, Rodgers A, Murray CJL, eds. Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attribution to Selected Major Risk Factors. Vol 1. Geneva: World Health Organization, 2004:163-209.
2. Stoltzfus RJ. Iron-deficiency anemia: reexamining the nature and magnitude of the public health problem. Summary: implications for research and programs. J Nutr 2001;131:697S-700S.
3. Brotanek JM, Halterman J, Auinger P, et al. Iron deficiency, prolonged bottle-feeding, and racial/ethnic disparities in young children. Arch Pediatr Adolesc Med 2005;159:1038-42.
4. Lozoff B, Beard J, Connor J, et al. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev 2006; 64:S34-43. (Pubitemid 44606856)
5. Lozoff B. Iron deficiency and child development. Food Nutr Bull 2007;28:S560-71.
6. Fuglestad AJ, Lehmann AE, Kroupina MG, et al. Iron deficiency in international adoptees from Eastern Europe. J Pediatr 2008; 153:272-7.
7. Lozoff B, De Andraca I, Castillo M, et al. Behavioral and developmental effects of preventing iron-deficiency anemia in healthy full-term infants. Pediatrics 2003;112:846-54.
8. Roncagliolo M, Garrido M, Walter T, et al. Evidence of altered central nervous system development in young iron deficient anemic infants: delayed maturation of auditory brainstem responses. Am J Clin Nutr 1998;68:683-90.
9. Angulo-Kinzler RM, Peirano P, Lin E, et al. Spontaneous motor activity in human infants with iron-deficiency anemia. Early Hum Dev 2002;66:67-79. (Pubitemid 34168484)
10. Angulo-Kinzler RM, Peirano P, Lin E, et al. Twenty-four-hour motor activity in human infants with and without iron-deficiency anemia. Early Hum Dev 2002;70:85-1014.
11. Peirano P, Algarín C, Garrido M, et al. Iron-deficiency anemia is associated with altered characteristics of sleep spindles in NREM sleep in infancy. Neurochem Res 2007;32:1665-72.
12. Algarín C, Peirano P, Garrido M, et al. Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning. Pediatr Res 2003;53:217-23.
13. Peirano P, Algarín C, Garrido M, et al. Iron deficiency anemia (IDA) in infancy is associated with altered sleep states organization in childhood. Pediatr Res 2007;62:715-9.
14. Bredesen DE. Neural apoptosis. Ann Neurol 1995;38:839-51.
15. Hughes PE, Alexi T,Walton M, et al. Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis related genes within the central nervous system. Prog Neurobiol 1999;57:421-50.
16. Caviness VS Jr. Normal development of cerebral neocortex. In: Evrard P, Minkowski A (eds). Developmental neurobiology. New York City: Raven Press; 1989. pp. 1-10.
17. O'Brien LM, Gozal D. Neurocognitive dysfunction and sleep in children: from human to rodent. Pediatr Clin North Am 2004; 51:187-202.
18. Finn Davis K, Parker KP, Montgomery GL. Sleep in infants and young children: part two: common sleep problems. J Pediatr Health Care 2004;18:130-7.
19. Cao M, Guilleminault C. Sleep difficulties and behavioral outcomes in children. Arch Pediatr Adolesc Med 2008;162:385-9.
20. Peirano P, Algarín C, Uauy R. Sleep-wake states and their regulatory mechanisms throughout early human development. J Pediatr 2003;143:S70-9.
21. Steriade M, Deschenes M, Domich L, et al. Abolition of spindle oscillations in thalamic neurons disconnected from nucleus reticularis thalami. J Neurophysiol 1985;54:1473-97. (Pubitemid 16148985)
22. Ellingson RJ. Development of sleep spindle bursts during the first year of life. Sleep 1982;5:39-46.
23. Louis J, Zhang JX, Revol M, et al. Ontogenesis of nocturnal organization of sleep spindles: a longitudinal study during the first 6 months of life. Electroencephalogr clin Neurophysiol 1992; 83:289-96.
24. Steriade M. Coherent oscillations and short-term plasticity in corticothalamic networks. Trends Neurosci 1999;22:337-45.
25. Rosanova M, Ulrich D. Pattern-specific associative long-term potentiation induced by a sleep spindle-related spike train. J Neurosci 2005;25:9398-405.
26. Walker MP, Stickgold R. Sleep, memory and plasticity. Annu Rev Psychol 2006;57:139-66.
27. Yoo SS, Hu PT, Gujar N, et al. A deficit in the ability to form new human memories without sleep. Nat Neurosci 2007; 10:385-92.
28. Hasselmo ME. Neuromodulation: acetylcholine and memory consolidation. Trends Cogn Sci 1999;3:351-9.
29. Buzsáki G. Two-stage model of memory trace formation: a role for "noisy" brain states. Neuroscience 1989;31:551-70.
30. Schmidt C, Peigneux P, Muto V, et al. Encoding difficulty promotes postlearning changes in sleep spindle activity during napping. J Neurosci 2006;26:8976-82.
31. Peirano P, Algarín C. Sleep in brain development. Biol Res 2007;40:471-8.
32. Parmelee AH, Sigman M, Garbanati J, et al. Neonatal electroencephalographic organization and attention in early adolescence. In: Dawson G, Fischer KW (eds). Human Behavior and the Developing Brain. New York: Guilford; 1994. pp. 537-54.
33. Kordas K, Siegel EH, Olney DK, et al. Maternal reports of sleep in 6-18 month-old infants from Nepal and Zanzibar: association with iron deficiency anemia and stunting. Early Hum Dev 2008; 84:389-98.
34. Scher A. Infant sleep at 10 months of age as a window to cognitive development. Early Hum Dev 2005;81:289-92.
35. Allen RP, Barker PB, Wehrl F, et al. MRI measurement of brain iron in patients with restless legs syndrome. Neurology 2001; 23,56:263-5.
36. Simakajornboon N, Gozal D, Vlasic V, et al. Periodic limb movements in sleep and iron status in children. Sleep 2003; 26:735-8. (Pubitemid 39619785)
37. Konofal E, Cortese S, Marchand M, et al. Impact of restless legs syndrome and iron deficiency on attention-deficit/hyperactivity disorder in children. Sleep Med 2007;8:711-5.
38. Picchietti MA, Picchietti DL. Restless legs syndrome and periodic limb movement disorder in children and adolescents. Semin Pediatr Neurol 2008;15:91-9.
39. Felt BT, Beard JL, Schallert T, et al. Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats. Behav Brain Res 2006;171:261-70.
40. Clardy SL, Wang X, Zhao W, et al. Acute and chronic effects of developmental iron deficiency on mRNA expression patterns in the brain. J Neural Transm 2006;71:173-96.
41. Wang X,Wiesinger J, Beard J, et al. Thy1 expression in the brain is affected by iron and is decreased in restless legs syndrome. J Neurol Sci 2004;220:59-66.
42. Todorich B, Pasquini JM, Garcia CI, et al. Oligodendrocytes and myelination: the role of iron. Glia 2008.
43. Rao R, Tkac I, Townsend EL, et al. Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus. J Nutr 2003;133:3215-21. (Pubitemid 37222244)
44. Beard JL, Connor JR. Iron status and neural functioning. Ann Rev Nutr 2003;23:41-58.
45. Burhans MS, Dailey C, Beard Z, et al. Iron deficiency: differential effects on monoamine transporters. Nutr Neurosci 2005; 8:31-8.
46. Beard JL, Felt B, Schallert T, et al. Moderate iron deficiency in infancy: biology and behavior in young rats. Behav Brain Res 2006;170:224-32.
47. Ward K, Tkac I, Jing Y, et al. Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats. J Nutr 2007;137:1043-9.
48. Golub MS, Hogrefe CE, Germann SL, et al. Behavioral consequences f developmental iron deficiency in infant rhesus monkeys. eurotoxicol Teratol 2006;28:3-17.
49. Lozoff B, Jimenez E, Hagen J, et al. Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics 2000;105:E51.
50. Benca RM, Obermeyer WH, Thistead RA, et al. Sleep and psychiatric disorders: a meta-analysis. Arch Gen Psychiatry 1992; 49:651-68.
51. Carlson ES, Stead JDH, Neal CR, et al. Perinatal iron deficiency results in altered developmental expression of genes mediating energy metabolism and neuronal morphogenesis in hippocampus. Hippocampus 2007;17:679-91.
52. Schmidt AT, Waldow KJ, Grove WM, et al. Dissociating the longterm effects of fetal/neonatal iron deficiency on three types of learning in the rat. Behav Neurosci 2007;121:475-82.
53. de Ungria M, Rao R, Wobken JD, et al. Perinatal iron deficiency decreases cytochrome c oxidase (CytOx) activity in selected regions of neonatal rat brain. Pediatr Res 2000;48:169-76.
54. McEchron MD, Cheng AY, Liu H, et al. Perinatal nutritional iron deficiency permanently impairs hippocampus-dependent trace fear conditioning in rats. Nutr Neurosci 2005;8:195-206.
55. Jones BC, Beard JL, Gibson JN, et al. Systems genetic analysis of peripheral iron parameters in the mouse. Am J Physiol Regul Integr Comp Physiol 2007;293:R116-24.
56. Burden MJ, Westerlund AJ, Armony-Sivan R, et al. An eventrelated potential study of attention and recognition memory in infants with iron deficiency anemia. Pediatrics 2007; 120:e336-45.
57. Dzirasa K, Ribeiro S, Costa S, et al. Dopaminergic control of sleepwake status. J Neuroscience 2006;26:10577-89.
58. Monti JM, Monti D. The involvement of dopamine in the modulation of sleep and waking. Sleep Med Rev 2007; 11:113-33.
59. Crochet S, Sakai K. Dopaminergic modulation of behavioural states in mesopontine tegmentum: a reverse microdialysis study in freely moving cats. Sleep 2003;26:801-6.
60. Fuller PM, Gooley JJ, Saper CB. Neurobiology of the sleep-wake cycle: sleep architecture, circadian regulation, and regulatory feedback. J Biol Rhythms 2006;21:482-93.
61. McCarley RW. Neurobiology of REM and NREM sleep. Sleep Med 2007;8:302-30.
62. Rye DB. Contributions of the pedunculopontine region to normal and altered REM sleep. Sleep 1997;20:757-88.
63. Mena-Segovia J, Bolam JP, Magill PJ. Pedunculopontine nucleus and basal ganglia: distant relatives or part of the same family? Trends Neurosci 2004;27:585-8.
64. Lu J, Sherman D, Devor M, et al. A putative flip-flop switch for control of REM sleep. Nature 2006;441:589-94.