Iron deficiency anemia in infancy: Long-lasting effects on auditory and visual system functioning

Pediatric Research

Volumn 53, Issue 2, 2003, Pages 217-223

  Algarín, Cecilia ^a   Peirano, Patricio ^a   Garrido, Marcelo ^a   Pizarro, Felipe ^a   Lozoff, Betsy ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BRAIN MATURATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; EVOKED AUDITORY RESPONSE; EVOKED VISUAL RESPONSE; FEMALE; HUMAN; IRON DEFICIENCY ANEMIA; LATENT PERIOD; MALE; MYELINATION; PRIORITY JOURNAL;

ANEMIA, IRON-DEFICIENCY; CHILD; CHILD, PRESCHOOL; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, AUDITORY; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; EVOKED POTENTIALS, VISUAL; FEMALE; FERROUS COMPOUNDS; FOLLOW-UP STUDIES; GESTATIONAL AGE; HUMANS; INFANT; MALE; REACTION TIME; REFERENCE VALUES;

EID: 0037313166     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.PDR.0000047657.23156.55     Document Type: Article

References (52)

1. Jewett DL, Romano MN, Williston JS 1970 Human auditory evoked potentials: possible brainstem components detected on the scalp. Science 167:1517-1518
2. Jewett DL, Williston JS 1970 Auditory evoked far fields averaged from the scalp in humans. Brain 94:681-696
3. Moller AR, Janetta PJ 1982 Evoked potentials from the inferior colliculus in man. Electroencephalogr Clin Neurophysiol 53:612-620
4. Mochizuki Y, Go T, Ohkubo H, Tatara T, Motomura T 1982 Developmental changes of brainstem auditory evoked potentials (BAEPs) in normal human subjects from infants to young adults. Brain Dev 4:127-136
5. Tsuneishi S, Casaer P 1997 Stepwise decrease in VEP latencies and the process of myelination in the human visual pathway. Brain Dev 19:547-551
6. Moller AR, Janetta PJ, Moller MB 1981 Neural generators of brainstem evoked potentials: results from human intracranial recordings. Ann Otol Rhinol Laryngol 90:591-596
7. Moore JK, Linthicum FHJ 2001 Myelination of the human auditory nerve: different time courses for Schwann cell and glial myelin. Ann Otol Rhinol Laryngol 110:655-661
8. Roncagliolo M, Garrido M, Walter T, Peirano P, Lozoff B 1998 Evidence of altered central nervous system development in infants with iron deficiency anemia at 6 mo: delayed maturation of auditory brain stem responses. Am J Clin Nutr 68:683-690
9. Larkin EC, Rao GA 1990 Importance of fetal and neonatal iron: adequacy for normal development of central nervous system. In: Dobbing J (ed) Brain, Behaviour, and Iron in the Infant Diet. Springer-Verlag, London, pp 43-62
10. Connor JR, Benkovic SA 1992 Iron regulation in the brain: histochemical, biochemical, and molecular considerations. Ann Neurol 32:S51-S61
11. Connor JR, Menzies SL 1990 Altered cellular distribution of iron in the central nervous system of myelin deficient rats. Neuroscience 34:265-271
12. Yu GS, Steinkirchner TM, Rao GA, Larkin EC 1986 Effect of prenatal iron deficiency on myelination in rat pups. Am J Pathol 125:620-624
13. Jiang ZD 1995 Maturation of the auditory brainstem in low risk-preterm infants: a comparison with age-matched full term infants up to 6 years. Early Hum Dev 42:49-65
14. Salamy A, McKean CM 1976 Post-natal development of human brainstem potentials during the first year of life. Electroencephalogr Clin Neurophysiol 40:418-426
15. Hecox K, Burkard R 1982 Developmental dependencies of the human brainstem auditory evoked response. Ann N Y Acad Sci 388:538-556
16. Russo FDI, Martinez A, Sereno MI, Pitzalis S, Hillyard SA 2001 Cortical sources of the early components of the visual evoked potential. Hum Brain Mapping 15:95-111
17. Lozoff B, De Andraca I, Castillo M, Walter T, Smith J, Pino P 2001 Behavioral and developmental benefits of preventing iron deficiency anemia in healthy full-term infants. Pediatr Res 49:24A
18. Dallman PR, Reeves JD, Driggers DA, Lo EYT 1981 Diagnosis of iron deficiency: the limitations of laboratory tests in predicting response to iron treatment in 1-year-old infants. J Pediatr 98:376-381
19. Nathan DG, Orkin SH 1998 Hematology of Infancy and Childhood, 5th Ed. WB Saunders, Philadelphia
20. Dallman PR, Siimes MA 1979 Percentile curves for hemoglobin and red cell volume in infancy and childhood. J Pediatr 94:26-31
21. Deinard AS, Schwartz S, Yip R 1983 Developmental changes in serum ferritin and erythrocyte protoporphyrin in normal (nonanemic) children. Am J Clin Nutr 38:71-75
22. Bryk A, Raudenbush SW 1992 Hierarchical Linear Models: Applications and Data Analysis Methods, Sage Publications, Newbury Park, CA
23. Eggermont JJ, Salamy A 1988 Maturational time course for the ABR in preterm and full term infants. Hearing Res 33:35-47
24. Kos-Pietro S, Towle VL, Cakmur R, Spire JP 1997 Maturation of human visual evoked potentials: 27 weeks conceptional age to 2 years. Neuropediatrics 28:318-323
25. Paus T, Collins DL, Evans AC, Leonard G, Pike B, Zijdenbos A 2001 Maturation of white matter in the human brain: review of magnetic resonance studies. Brain Res Bull 54:255-266
26. Connor JR, Menzies SL 1996 Relationship of iron to oligodendrocytes and myelination. GLIA 17:83-93
27. Rudell AP 1987 A fiber tract model of auditory brain-stem responses. Electroencephalogr Clin Neurophysiol 67:53-62
28. Li YY, Wang HM, Wang WG 1994 The effect of iron deficiency anemia on the auditory brainstem response in infant. Natl Med J China 74:367-369
29. Sarici SU, Serdar MA, Dundaroz MR, Unay B, Akin R, Deda G, Gokcay E 2001 Brainstem auditory-evoked potentials in iron-deficiency anemia. Pediatr Neurol 24:205-208
30. Sarici SU, Okutan V, Dundaroz MR, Serdar AM, Akin R, Deda G, Gokcay E 2001 The effect of iron supplementation on visual-evoked potentials in infants with iron deficiency anemia. J Trop Pediatr 47:132-135
31. Erikson K, Pinero DJ, Connor JR, Beard JL 1997 Regional brain iron, ferritin and transferrin concentrations during iron deficiency and iron repletion in developing rats. J Nutr 127:2030-2038
32. Sun AH, Xiao SZ, Li BS, Li ZJ, Wang TY, Zhang YS 1987 Iron deficiency and hearing loss. Experimental study in growing rats. ORL J Otorhinolaryngol Relat Spec 49:118-122
33. Sun AH, Wang ZM, Xiao SZ, Li ZJ, Zheng Z, Li JY 1992 Sudden sensorineural hearing loss induced by experimental iron deficiency in rats. ORL J Otorhinolaryngol Relat Spec 54:246-250
34. Lilienthal H, Winneke G 1996 Lead effects on the brain stem auditory evoked potential in monkeys during and after the treatment phase. Neurotoxicol Teratol 18:17-32
35. Lasky RE, Maier MM, Snodgrass EB, Hecox KE, Laughlin NK 1995 The effects of lead on otoacoustic emissions and auditory evoked potentials in monkeys. Neurotoxicol Teratol 17:633-644
36. Barnet AB, Weiss IP, Sotillo MV, Ohlrich ES, Shkurovich M, Cravioto J 1978 Abnormal auditory evoked potentials in early infancy malnutrition. Science 201:450-452
37. Bartel PR, Robinson E, Conradie JM, Prinsloo JG 1986 Brainstem auditory evoked potentials in severely malnourished children with kwashiorkor. Neuropediatrics 17:178-182
38. Grantham-McGregor S, Ani C 2001 A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr 131:649S-668S
39. Moffatt MEK, Longstaffe S, Besant J, Dureski C 1994 Prevention of iron deficiency and psychomotor decline in high risk infants through iron fortified infant formula: a randomized clinical trial. J Pediatr 125:527-534
40. Jahari AB, Saco-Pollitt C, Husaini M, Pollitt E 2000 Effects of energy and micronutrient supplementation on motor development and motor activity in undernourished children in Indonesia. Eur J Clin Nutr 54:S60-S68
41. Peirano P, Algarin C, Garrido L, Pizarro F, Roncagliolo M, Lozoff B 2001 Interaction of iron deficiency anemia (IDA) and neurofunctions in cognitive development. In: Fernstrom JD, Uauy R, Arroyo P (eds) Nutrition and Brain. Karger, Basel, pp 19-39
42. Nelson CA, Erikson K, Pinero DJ, Beard JL 1997 In vivo dopamine metabolism is altered in iron-deficient anemic rats. J Nutr 127:2282-2288
43. Antal A, Keri S, Bodis-Wollner J 1997 Dopamine D2 receptor blockade alters the primary and cognitive components of visual evoked potentials in the monkey, Maccaca fascicularis. Neurosci Lett 232:179-181
44. Wallace MT, Wilkinson LK, Stein B 1996 Representation and integration of multiple sensory inputs in primate superior colliculus. J Neurophysiol 76:1246-1266
45. Lozoff B, Jimenez E, Wolf AW 1991 Long-term developmental outcome of infants with iron deficiency. N Engl J Med 325:687-694
46. De Andraca I, Walter T, Castillo M, Pino P, Rivera P, Cobo C 1991 Iron deficiency anemia and its effects upon psychological development at preschool age: a longitudinal study. Nestle Foundation Nutrition Annual Report 1990. Nestec Ltd., Vevey. Switzerland, pp 53-62
47. Lozoff B, Jimenez E, Hagen J, Mollen E, Wolf AW 2000 Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics e51:1-11
48. DeUngria M, Rao R, Wobken JD, Luciana M, Nelson CA, Georgieff MK 2000 Perinatal iron deficiency decreases cytochrome c oxidase (CytOx) activity in selected regions of neonatal rat brain. Pediatr Res 48:169-176
49. Detterman DK 1987 What does reaction time tell us about intelligence? In: Vernon PA (ed) Speed of Information-Processing and Intelligence. Ablex, Norwood, NJ, pp 177-200
50. Kail R 1992 Processing speed, speech rate, and memory. Dev Psychol 28:899-904
51. Colombo J, Mitchell DW 1990 Individual differences in early visual attention: fixation time and information processing. In: Colombo J, Fagen J (eds) Individual Differences in Infancy: Reliability, Stability, Prediction. Erlbaum, Hillsdale, NJ, pp 193-227
52. Jacobson SW, Chiodo LM, Jacobson JL 1996 Predictive validity of infant recognition memory and processing speed to 7-year IQ in an inner-city sample. Inf Behav Dev 19:524