Trichostatin A blocks TGF-β-induced collagen gene expression in skin fibroblasts: Involvement of Sp1

Biochemical and Biophysical Research Communications

Volumn 354, Issue 2, 2007, Pages 420-426

  Ghosh, Asish K ^a   Mori, Yasuji ^a   Dowling, Elizabeth ^a   Varga, John ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Fibroblasts; Fibrosis; Histone acetyltransferase; Histone deacetylase; Smad; Sp1; TGF ; Trichostatin A; Type I collagen

Indexed keywords

COLLAGEN; HISTONE DEACETYLASE INHIBITOR; SMAD PROTEIN; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA; TRICHOSTATIN A;

ARTICLE; BINDING SITE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE INTERACTION; GENE REPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; SKIN FIBROBLAST;

CELLS, CULTURED; COLLAGEN; FIBROBLASTS; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; SP1 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 33846548599     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.12.204     Document Type: Article

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